造血

As HSCs mature from the long-term self-renewing pool to multipotent progenitors, they progressively lose their potential to self-renew but become more mitotically active.

由于造血干细胞是在长期的自我更新到多能干细胞的过程中成熟起来的，所以它们逐渐丧失了自我更新的能力，但是分裂变得更加活跃。

Methods We used Amphotericin B for fungous septicemia complicated with allo-geneic hematopoietic stem cell transplantation (2 cases of server aplastic anemia, 1 case of acute lymphoblastic leukemia) or chemotherapy (2 cases of chronic lymphoblastic leukemia,5 cases of acute monoblastic leukemia). The long-term of one to three months Amphotericin B was used at total dose range from 1750 to 3115 microgram with drug prophylaxis and care.

对异基因造血干细胞移植3例（SAA 2例、ALL 1 例）和白血病化疗后7例（CLL 2例、M55例），出现真菌性败血症时应用长程（1～3个月）的两性霉素B治疗，总剂量为1750～3115 mg，观察其疗效和并发症，且对并发症采用药物预防和护理。

Methods: Using the techniques of cell culture ex vivo, flow-cytometry, immunocytochemistry, the effects of GPS on the proliferation of human promyelocytic leukemia cell line(HL-60) and human granulocytopoiesis and monocytopoiesis were observed.

结果：GPS在体外能抑制HL-60细胞增殖，而同等剂量的GPS能明显促进正常粒单系造血祖细胞的增殖分化；在本实验条件下未见GPS对HL-60细胞有明显的诱导分化作用。

There are four categories of paraneoplastic syndromes - hematological, neurological, mucocutaneous, and endocrine/metabolic.

副肿瘤综合征累及四个系统，造血系统，神经系统，粘膜皮肤和内分泌和代谢系统。

MDS is a heterogeneous and common group of clonal hematological disorders characterized by a multi-step process which begins with a somatic mutation in the pluripotential stem cell, and a high rate of tranformation into acute myeloblastic leukemia.

MDS是造血干细胞恶性克隆性疾病，呈现多系改变、多阶段进展两大特征，最终往往发展成AML。

BACKGROUND: Allogeneic hematopoietic stem cell transplantation is recognized as the only method of curing chronic myelocytic leukemia.

背景：异基因造血干细胞移植是目前公认的惟一可以治愈慢性粒细胞白血病的方法，但存在供体来源少，移植相关并发症较多等问题。

Acute myelocytic leukemia is a malignant neoplasm of hematopoietic cells characterized is an abnormal proliferation of myeloid precursor cells.

急性前骨髓性白血病，是一种造血组织的恶性疾病，其治病原因乃骨髓性前趋细胞不正常的大量增生，并有细胞分化停止的病变。

Results There were three morphological types of BM metastasis of NB, microinvasive, moderately invasive and diffusely invasive pattern. CgA/NSE immunohistochemical staining was needed fur confirming the metastatic neuroblastic cells in microinvasion.

结果 神经母细胞瘤骨髓转移表现为微小浸润、中度浸润和弥漫浸润三种形式，主要根据骨髓造血组织与肿瘤成分的比例和分布而定，其中微小浸润常需行CgA/NSE免疫组化染色辅助诊断。

Bone marrow stromal cells are cells got rid of hemopoietic stem cells in marrow cell of mature individual, which is approved to be multi-differentiation potential including transforming into neural stem cell, and differentiation into neurs and neuroglial cell.

骨髓基质细胞(Bone marrow stromal cells，BMSCs)是成体骨髓细胞中除造血干细胞之外的另一类骨髓干细胞，近年来的研究证明其具有多向分化的潜能，包括向神经干细胞转化，并可进一步分化为神经元和神经胶质细胞。

After allowing 1 day for adherence to culture flask, nonadherent cells were removed.

三、脐带血造血前体细胞在间充质干细胞微环境中的增殖动力学研究。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。