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This paper reviews the pathways of ES cells in vitro being committed and differentiated to hematopoietic cells, cardiomyocytes, neural cells, adipocytes, pancreatic islets, endothelial cells, epithelia, osteoblasts, chondroblast and melanocytes.

文章综述了体外定向诱导ES细胞分化为造血细胞、心肌细胞、神经细胞、脂肪细胞、胰岛细胞、内皮细胞、上皮细胞、成骨细胞、软骨细胞和黑素细胞等的途径和方法。

In resent year, several in vitro models for committed differentiation of ES cells have been described which give rise to a variety of cell types, including hematopoietic, neuronal, chondroitic, osteocytic, endothelial, myogenic, cardiac and smoothes muscle cells, but the committed differentiation into epidermal stem cells have not been reported.

ES细胞为研究基因功能、胚胎发生和个体发育,及组织细胞分化机理提供了理想的模型。近年来的研究表明,适当条件下,ES细胞可定向分化为三个胚层的各种类型的细胞,其中包括向神经元、造血细胞、成骨细胞、心肌细胞、血管内皮、软骨细胞、平滑肌特方向的定向分化。

In adults of all species steroidogenic and catecholaminergic chromaffin cells were found in the head kidney,which is pronephric in origin and subsequently transformed into a hematopoietic lymphatic organ.

所有种类固醇和成人儿茶酚胺铬细胞被发现头部肾脏,这是起源于鳜随后转化淋巴造血器官。

Treatment for CNS lymphomas has also experienced some changes, and the best results are obtained using HAART, glucocorticoids, and methotrexate, with or without craniospinal radiation.

复发性系统性淋巴瘤预后很差,如果治疗条件很好,并且决定继续做治疗,就要考虑造血细胞的移植,治疗神经性淋巴瘤目前最好使用 HAART+激素+甲胺蝶呤,加或不加脑脊髓放疗。

Following the surgery the patient presented with right side weakness, unsteady gait, and speech difficulty. Rehabilitation programs, including physical therapy, occupational therapy and speech therapy, were scheduled. Craniospinal radiation therapy was also administered to prevent tumor recurrence.

术后个案因右侧肢体无力步态不稳,另外在口语表达也有障碍,因此转至复健科,除安排复健治疗外,也开始脑部脊髓放射治疗,治疗一周后出现食欲不振抽血发现有骨髓造血功能抑制现象,因此中断脑部脊髓放射治疗。

Meanwhile, the failures were represented in the devation between religion ideology and cultual policy practice, the relativity of political transparency and the denseness of smallholder consciousness.

政策失误表现在:宗教意识形态与文化政策实践中的偏差、政治透明的相对性、人才引进平等精神的变异、小农意识浓厚及造血功能的缺失等。

Objective:To explore the cytogenetic change after hematopoietic stem cell transplantation in patients with leukemia.

目的:探讨造血干细胞移植后白血病细胞染色体核型和基因表达观察的意义。

The bone dosimetric values are influenced by the parameters of skeleton mass.

鉴于骨骼组织不同部位的辐射敏感性存在差异[2],特别是已确认骨髓的造血干细胞和衬在骨表面上的成骨细胞是骨骼中致癌危险的靶细胞,因而ICRP30号出版物[3]详细介绍了估算骨骼靶器官的吸收剂量的骨剂量学模型,使骨剂量的计算趋向精确。1995年,ICRP又专门编著了用于辐射防护的骨骼解剖和生理参数的70号出版

Classification by histogenesis:(1) Primary tumor 6 679 cases: epitheliogenic 2 481 cases (37.15%), mesenchymal 753 cases (11.27%), lympho-hematopoietic 102 cases (1.53%), neurogenic 1 542 cases (23.09%), congenital abnormal embryogenetic 1 767 cases (26.46%), uncertain resource tumor 34 cases (0.50%).(2) Secondary tumor 13 cases;(3) Metastatic tumor 9 cases;(4) Non-tumor lesion 1 972 cases.

按组织发生学分类:(1)原发性肿瘤6 679例(77.01%),其中上皮组织肿瘤2 481例(37.15%),间叶组织肿瘤753例(11.27%),淋巴造血组织肿瘤102例(1.53%),神经组织肿瘤1 542例23.09%),先天胚胎发育异常肿瘤1 767例(26.46%),不明来源肿瘤34例(0.50%);(2)继发性肿瘤13例(0.15%;(3)转移性肿瘤9例(0.10%);(4)非肿瘤性病变1 972例(22.74%)。

Methods Systematic observations of clinical manifestations,hematopoietic function,chromosomal aberrations,immunologic neurological,endocrinological,reproductive functions,eye examination,asssay of HPRT gene mutation and detection of oncogenes were performed in the past six years.

持续6年对患者进行临床表现、造血功能、染色体畸变、免疫功能、神经系统、内分泌功能、生殖功能及眼晶体等检查和HPRT基因突变及某些癌基因检测。

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