造血

CD117; hemopoietic stem cells ; dendritic cells ; directional differentiation

CD117；造血干细胞；树突状细胞；定向分化

Mouse model has been appreciated valuable for dissecting the regulatory mechanisms of hematopoietic development.

作为重要模式生物的小鼠为造血发育提供了非常好的模型。

The activated donor-type NK cells could prevent gVHD and produce significant GVT effects and also resulted in greater hematopoietic reconstitution if they were at the initial stage of allogeneic BMT in mice. Thereafter, the activated donor-type NK cells were detrimental and could exacerbate the subsequent GVHD, these results also demonstrated that GVT and GVHD could be dissociable phenomena.

①在小鼠异基因骨髓移植的初始阶段，输注供鼠的活化NK细胞能促进造血重建，预防GVHD并同时增强移植物抗肿瘤效应；输注骨髓细胞之后，输注供鼠的活化NK细胞则起到加重GVHD的不良作用；②GVT和GVHD是能够被分开的。

Cumulative data have been documented that mesenchymal stem cells can differentiate into osteoblasts, chondrocytes, adipocytes, tenocytes, myotubes, neural-like cells, hematopoietic-supporting stroma and other non-hematopoietic cells derived from mesoblast or ectoblast.

大量研究表明，体外培养的骨髓间质干细胞在合适的诱导条件下，可分化为成骨细胞、成软骨细胞、脂肪细胞、成肌细胞、成腱细胞和神经元样细胞等多种非造血组织特别是中胚层和神经外胚层来源的组织细胞。

Methods We investigated retrospectively the engraftment of 48 patients infected with hepatitis B virus prior to transplantation among 185 patients of hematopoietic stem cell transplantation.

对我院1990年1月—2001年5月间185例造血干细胞移植的患者中，有HBV感染的48例患者的临床资料进行回顾性分析。

HBV infection interfered with the engraftment of hematopoietic stem cells

乙型肝炎病毒感染不影响造血干细胞的植活时间。

RESULTS: Hematopoietic stem cell engraftment was confirmed in all nine recipients.

结果：9名受者体内均证实存在供者造血干细胞。

Compared with ABO compatibility patients, this article analyzes the influence of ABO incompatibility on the red blood cell engraftment.

以同期ABO血型相合的受者作对照，分析ABO血型不合对异基因造血干细胞移植后红系重建的影响。

Within two months (56 days) of transplantation, all patients had evidence of initial multilineage donor hematopoietic cell engraftment.

在移植手术后两个月之内(56天)，所有患者都显示出多世系捐赠者造血细胞的初期移植反应。

Thus,acute radiation sickness of moderate degree was ascertained.It was deduced that 3 other members in Feng's family died of ARS.Altogether about 100 ictims were found.Conclusion When ealuating a patient with suspicious burn without a history of contact of heat or fire and caustic chemicals and the patient has nausea,omiting,epilation and decrease in white blood cells,the possibility of radiation exposure exists.If some patients with aboe manifestations are found in a same family the radiation exposore may be more probable.

如遇到难以解析的皮肤烧伤病变，排除热或化学烧伤后，应考虑放射烧伤，对有恶心，呕吐，脱发，口腔溃疡，外周血细胞减少者，更支持诊断；如家中成员中相继发生上述同类症状者更应高度怀疑，并作相关检查确诊；简易隔简可为一般医院所采用；细胞因子可促进造血功能恢复，缩短病程。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。