通路

Cancer or tumor dependence on methionine for growth is an artificial condition, brought about by some earlier failure in the transsulfuration and transmethylation pathways.

癌症或肿瘤生长依赖蛋氨酸是一种人工条件一些较早失败带来的transsulfuration和转移通路。

He TandemHeart percutaneous transseptal ventricular assist system is a left ventricular assist device designed to be used as a short-term circulatory support system for procedures not requiring complete cardiopulmonary bypass.

andemHeart经由皮肤跨隔膜心室辅助系统是一种左心室辅助设备，设计作为短期循环支持系统，不需要彻底的心肺通路手术。

The TandemHeart percutaneous transseptal ventricular assist system is a left ventricular assist device designed to be used as a short-term circulatory support system for procedures not requiring complete cardiopulmonary bypass.

一种短期体外循环支持系统能够经由皮肤心脏导管手术，在30分钟内提供心脏辅助支持功能。TandemHeart经由皮肤跨隔膜心室辅助系统是一种左心室辅助设备，设计作为短期循环支持系统，不需要彻底的心肺通路手术。

When the coronary sinus is unsuitable for transvenous biventricular pacing, a transseptal approach from the right to left atrium can allow endocardial left ventricular pacing with permanent anticoagulant therapy, instead of epicardial pacing via the branches of the coronary sinus.

当冠脉窦不适合经静脉双腔起搏后，右房至左房的隔膜通路手术需要经永久抗凝血疗法后进行左心室内膜起搏手术，而不是经冠脉窦分支的心外膜起搏。

Objective To clone and characterize a RRas-like gene from Trichomonas vaginalis for studying cellular signal transduction pathways in the organism.

摘要目的克隆和分析阴道毛滴虫RRas同源基因，以探讨其在细胞内信号传导通路中的功能。

In a point to point encryption of the TETRA system, the trunking system does not participate in the key generation and management, and only provides the clear channel for transportation.

在TETRA 系统的端到端加密中，集群系统不参与密钥的产生和管理，也不规定加密算法，只提供透明传输通路。

The main aspect that makes wireless security different than security of wired networks is the uncontrollability of physical access due to transmission of data with radio waves.

由于数据的传输，使无线的安全不同胜于以线加强网络的安全的主要的方面以电波是身体通路的无法控制性。

So the neural pathways that underly the septo-hippocampal CA1 LTP remains to be revealed.

故隔-海马CA1区LTP现象的神经通路基础有待揭示。

In this thesis, we find that dlg is indispensible in the establishment of anterior-posterior and dorsal-ventral polarity of drosophila oocyte. Removal of Dlg function from the posterior follicle cells using the FLP/FRT system leads to disruption of oocyte skeleton reconstruction that is elicited by the failure of those posterior cells to differentiate normally in mid-oogenesis. We demonstrate that abnormity of Notch, JAK-STAT and EGFR signal pathway in dlg mutants contributes to this aberrant differentiation. dlg null mutant also blocks the normal differentiation of two groups of anterior follicle cell-stretched cell and centripetal cell, but not border cell, with a lower penetrance. However unlike the result in posterior follicle cells, Notch and JAK-STAT signaling are both undisrupted in all mutant anterior follicle cells, implying other fate determinants may be involved.

我们的研究发现，后端滤泡细胞中的Dlg在果蝇卵子发生中期卵母细胞前后轴和背腹轴建立过程中也是必须的，PFC中dlg完全缺失型突变引起PFC的分化异常，导致卵子发生中期卵母细胞骨架重组异常，Stau、Grk等极性决定蛋白定位错误。dlg突变阻碍了Notch、JAK-STAT、EGFR等调节PFC分化的信号通路的激活。dlg突变的PFC也没有获得前端滤泡细胞命运。dlg突变不影响前端滤泡细胞群中边界细胞的分化，但是在一定程度上影响伸展细胞和向心细胞的分化，并且这种影响不依赖于前端滤泡细胞Notch或JAK-STAT信号激活的异常。

Furthermore, preliminary work also performed to examine whether PI3K/AKT signal transduction pathway was activated in the process of refractory leukemia development. Materials and methods An immortalized human bone marrow stromal cell line, HS-5, was introduced to establish a bi-phase culture system for the cultivation of B-lineage precursor leukemia cells. ELISA and RT-PCR were used to investigate the expression of VEGF and its receptors in the leukemia cell lines and primary childhood leukemia cells in different treated groups. Flow cytometory method and immunofluorescent staining were employed to examine the apoptosis signals both in the VP16 treated and untreated leukemia cells. Western blot was utilized to explore the PI3K/AKT activated status in the drug induced or uninduced leukemia cells and lymphocytes from healthy donors.

材料和方法使用来源于人类骨髓基质细胞的细胞株HS-5作为滋养层细胞进行急性淋巴细胞性白血病细胞的体外培养，通过细胞生物学和免疫学方法评估培养体系并鉴定出难治性白血病细胞克隆；以ELISA和RT-PCR方法检测急性白血病细胞株和患儿白血病细胞VEGF及其受体的表达，了解不同治疗阶段VEGF及其受体的表达状况，并结合临床指标进行分析，明确VEGF及其受体在白血病发生过程中的作用；流式细胞仪和免疫荧光染色法对正常健康儿童、初发白血病患儿、复发白血病患儿及缓解后患儿进行凋亡因子检测和分析，初步阐明难治性白血病抗凋亡形成的原因；蛋白印记分析检测PI3K/AKT信号传导通路在健康儿童、初发白血病和复发白血病患儿的表达，初步了解难治性白血病形成的分子生物学机制。

What would he tell Judith and the children?

他将怎样告诉朱迪丝和孩子们呢？

I this is at that time, the opinion with peacockish true girl is full of in a heart.

这就是当时的我，一个心中布满虚荣的女孩子真实的想法。