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Western Blot indicated that AIF was selectively released before cytochrome C from the intermembrane space of mitochondria to cytosol, and that release needed Bax relocation to mitochondria. Results above suggest that caspase-independent cell death maybe occurred earlier than caspase-dependent cell death in staurosporine induced T lymphocytes apoptosis. Caspase-independent cell death is an alternative pathway of cell death which could guarantee the safe and noninflammatory removal of corpses when caspase was mutented or blocked in the cell, it plays an important role in maintaining the number of T lymphocytes and ensuring the proper function of immune system.

细胞caspase非依赖死亡方式可能是Caspase依赖性死亡方式的替代途径,它可以保证在Caspase发生突变或通路受阻时,T细胞仍然能够正常死亡,这对于维持T细胞的数量和保证免疫系统正常功能的发挥具有十分重要的意义。

Luciferase assay and CREB knock-down experiments further demonstrate that CREB is involved in the transcriptional upregulation of Noxa.

有意思的是,Mcl-1的蛋白水平也可以通过P13K/Akt信号通路而被CPT上调。

As revealed by the voltage topographic maps and the tomographic mapping, the source location of the distinct N1 is in the occipitotemporal areas.

并且,与单纯形状知觉任务相比,图形形状和空间位置知觉任务表现枕颞区N2波幅的显著减弱,P3潜伏期的王著缩短,额区的P2波幅的显著减弱;(3)脑电地形图与高分辨率断层成象显示,两种任务的特征波N1成分均来源于双侧的枕颞皮层,表明两种任务均涉及到与物体形状识别相关的视皮层腹侧通路,而差别波dN2成分来源于左侧枕颞区,暗示特征加工的差异主要发生在左侧枕颞区。

We found that over-expression of the Notch ligand, Jagged-1, activated the Notch signaling pathway in DPSCs. Jagged-1 inhibited the odontoblastic differentiation of DPSCs in vitro.

Notch配体Jagged-1的过表达能激活DPSCs的Notch信号通路,在体外抑制成牙本质细胞谱系分化。

The above results indicated that the localization of NPY immunoreactive neurons in New Jianghan chicken's medulla oblongata was similar to those in broiler,silky fowl and rat, and the inferior olivary nucleus might be important position where NPY is transconducted from medulla oblongata to cerebellum.

表明,江汉鸡延髓NPY阳性神经元的分布与肉鸡、乌鸡、大鼠的大体相似;下橄榄核可能是NPY在延髓-小脑传递通路中的一个重要枢纽。神经肽Y;SABC法;延髓;江汉鸡

The study of cellular oncosis is still at the primary phase, and people lack efficient method to identify the oncosis and unreveal the pathology significance of oncosis in cardiovascular diseases.

尽管目前尚缺乏鉴别细胞胀亡的有效方法,限制了细胞胀亡在心血管疾病中病理意义的揭示,但通过信号通路研究,有望找到细胞胀亡的标志性蛋白;有利于心血管疾病防治建立崭新的靶点。

It stroke my heart when i read Pathway of Peace,my eyes are filled with tears, will we be able to comprehend His love for us, its so unbelievabe that we are able to love oneanother the way He loves us.

当我看到我的心它中风通路和平,我的眼睛充满泪水才能理解他对我们的爱,它使我们得以在unbelievabeoneanother爱他爱我们的方式。

Now, the investigation in TGF-β/Smad signal transduction mainly concentrate on gastroenteric tumor such as pancreatic carcinoma but few reports on orary cancer.

目前,对TGF-β/Smad信号通路的研究主要集中在胰腺癌等胃肠道肿瘤和血液肿瘤上,对卵巢癌的研究报道较少。

Thus, the components of Rb pathway may be potential targets for molecular intervention in patients with oropharyngeal squamous cell carcinoma

该传导通路的相关因子有可能成为治疗口咽癌的靶标记物。

Our results indicate that the Rb pathway plays a vitally important role for the clinical outcome in oropharyngeal squamous cell carcinoma.

视网膜母细胞瘤基因通路在口咽癌的发展演变中起到了重要的作用。

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What would he tell Judith and the children?

他将怎样告诉朱迪丝和孩子们呢?

I this is at that time, the opinion with peacockish true girl is full of in a heart.

这就是当时的我,一个心中布满虚荣的女孩子真实的想法。

Oh, and I bought myself a new laptop," he said."

哦,我还给我自己买了一个新笔记本"他说。"