通路

Objective: Bletilla Striata polysaccharide was used to stimulate the whole blood of the ICR mice. The mRNA and protein levels of all the inflammatory factors and coagulation factors in the whole blood were determined at different time intervals in order to investigate the molecular mechanism of BSP on the pathway of inflammation and coagulation. Methods:The whole blood was obtained from the ICR mice and stimulated by BSP.

目的：用白芨多糖刺激全血，检测不同刺激时间全血中各种炎症因子和凝血因子在mRNA水平和蛋白质水平的表达量，探讨白芨多糖作用于炎症和凝血通路的分子机制。

Mannitol challenge also has a tussive effect that is independent of bronchoconstriction, suggesting different physiologic pathways.

甘露醇同时具有诱发咳嗽的作用，该作用不依赖于支气管收缩，表明该作用与其诱导的支气管反应具有不同的生理学作用通路。

To reseach the mechanisms of ED wtih DM from the acpects of endocrinology, morphology and molecular biology, using rats from NDM and STZ groups as control, the concentration of testosterone, LH and FSH in sera, the microstructure of testicular tissue, bulbocavernous and ischiocavernous muscle tissue, and penile cavernous tissue, the ultrastructure of penile cavernous tissue, and the expression of nNOS mRNA, the content of nNOS and eNOS, the activity of NOS and the concentration of cGMP in the pathway of LARG-NO-cGMP in penile cavernous tissue from ED rats with DM were reseached or examinated in Group A, B and C.

本实验利用第一部分所建立的DM性ED模型，采用NDM及STZ大鼠作对照，通过对A组、B组及C组DM性ED大鼠血清中睾酮、LH及FSH浓度的测定，睾丸组织形态结构的研究从内分泌方面探讨DM性ED的发病机理；通过对阴茎海绵体组织显微及超微结构和球海绵体肌及坐骨耻骨肌显微结构的研究，首次从形态学方面探讨DM性ED的发病机理；通过对阴茎海绵体组织L-ARG-NO-cGMP通路中nNOS mRNA表达、nNOS及eNOS含量、NOS活性及cGMP浓度的检测，从分子生物学方面探讨DM性ED的发病机理。

AIM: To investigate alteration and cross link of the aortic and platelet endogenous L-arginine/NOS/NO pathway induced by septic shock. METHODS: The septic shock model was made in rats by caecal ligation and puncture.

目的：观察感染性休克对大鼠血小板及血管L-精氨酸/一氧化氮合酶/一氧化氮通路的影响及其相互联系，探讨感染性休克损伤的机制。

Methods:Forty-one stroke patients(13 patients were functional unit of brain cortex injury,28 patients were internal capsula or basal nucleus injury)were treated with physical therapy and occupational therapy.

对13例功能单位损伤和28例内囊、基底节等传导通路损伤的患者，在康复治疗的过程中定期进行疗效评价。

Objective: To investigate the effect and mechanism of JAK2/STAT3 pathway on myocardial protection of tetrodotoxin cardioplegia in rat hearts.

目的：探讨JAK2/STAT3信号通路在河豚毒素(tetrodotoxin， TTX)心脏停搏液保护缺血再灌注心肌中的作用及其机制。

The present study was designed to investigate whether histamine is involved in the protective effect of carnosine on Aβ42-induced impairment in differentiated PC12 cells.

因此本实验的主要目的是检测肌肽对Aβ42诱导的神经兴奋性损伤是否具有保护作用，肌肽-组胺酸-组胺通路是否参与其保护机制，谷氨酸含量，NMDA受体表达及功能在这一过程中是否受到影响，最终阐明肌肽保护作用的具体机制。

Whenever possible, access was limited to a left standard cervical approach anterior to the carotid sheath extended caudally.

尽可能将手术通路限制于颈动脉鞘前方标准颈部左侧入路，可向其尾端扩大范围。

However, it is not known how orthodontic force influences the function of cementoblast and what is the relationship between the function change of cementoblast with root resorption. So we studied the effect of mechanical stimuli on root resoption by examining the expression OPG and RANKL and exploring the related signal transduction pathway in cementoblast. Methods: Cementoblasts OCCM30 were cultured in DMEM with 10% FBS for 48 hours and starved in DMEM with no FBS for 24 hours, then subjected to mechanical strain by four-point bending system with tension and compression stress at 2000μstrain at 0.5Hz frequency. The flow cytometry was used to examine the cell cycle and proliferation activity after 3h, 6h, 12h, 24h loading respectively. OPG and RANKL mRNA were analysed with real time quantitive RT-PCR after the same loading period as FCM.

本课题利用四点弯曲力学加载系统，采用流式细胞术、实时荧光定量PCR、Western免疫印迹等方法，研究体外培养的成牙骨质细胞株OCCM-30在不同力学环境中增殖活性的变化，以及其表达骨保护素和破骨细胞分化因子的mRNA的变化，探讨应力刺激对成牙骨质细胞表达破骨细胞分化调控蛋白的影响，并通过对应力刺激下成牙骨质细胞分裂原活化蛋白激酶家族中的ERK1/2、P38MAPK活性的变化及其与OPG、RANKL基因表达变化关系的研究，对力学刺激调节破骨细胞分化调控蛋白的相关上游信号转导通路进行初步探讨。

Non-mitogenetic acidic fibroblast growth factor ; Re ceptor ; Signal pathway

非促分裂人酸性成纤维细胞生长因子；受体；信号通路

What would he tell Judith and the children?

他将怎样告诉朱迪丝和孩子们呢？

I this is at that time, the opinion with peacockish true girl is full of in a heart.

这就是当时的我，一个心中布满虚荣的女孩子真实的想法。