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Active MAPKs translocate into nucleus and thus regulate gene expression. Now, three main parallel pathways of MAPK family have been discovered : ERK1/2, JNK and p38. They can induce different gene expression and thus cause different cell reaction.

现已发现MAPK家族主要有三条平行的信号转导通路:ERK1/2、JNK和p38,三条通路可以活化不同的转录因子,启动不同的基因表达,从而引发不同的细胞反应。

Our research try to block the upstream of transmembrane signal transduction in order to provide the basis for the mechanism and clinical therapy of VILI.

本研究试图从信号转导通路的上游阻断各种信号转导通路的激活,从而为VILI的致病机理和临床治疗提供依据。

Research Direction Our research try to block the activation of transmembrane signal transduction related to inflammation by blocking the receptor of cellular membrane.

研究方向细胞内信号转导通路的激活要通过细胞膜受体的介导,本研究拟阻断细胞膜受体的激活,从而阻断肺细胞内各种炎症相关性信号转导通路的激活。

However, the growth of the cage aquaculture of Cobia is slow in the past which can be ascribed to the lacking of efficient manufacturer - retailer channel. In addition, the self benefit-based initiation results in a deficiency of cooperation between different members of the supply chain and market access has not established leading to the increase of cost as well as the lowering of profit of supplier. Consumers also cannot obtain the products with a reasonable price.

然而,以往海鲡鱼箱网养殖产业发展一直无法有效突破,影响的因素,不是养殖技术的问题,主要是产销通路的问题,同时现行产销供应链中各层级业者皆以追求自身的利益为出发点,缺乏上、中、下游的合作关系,再加上长期未能建构有效的市场通路造成成本增加,使生产者无法获得应有之利润,消费者亦无法享受到合理的价格。

These pathogens usually target more than one intracellular pathway and often interact at several points in each of these pathways to commandeer them fully.

病原菌会作用于不止一个胞内通路而且通常会同时作用于多个节点,从而完全霸占这些通路

The cap device includes a cap body having an inside transfer path for connecting an inlet opening for introducing the fuel and an outside transfer pipe, a fixed outer cap including a connector for fixing a discharge opening into which the transfer pipe is inserted, and an elastic opening/closing section in which the cap body is elastically compressible by the connector, and wherein the inside transfer path opens during the compression.

盖帽体具有用于将引导燃料的入口和外部输送管连接的内部输送通路。被固定的外盖帽包括使内部插有被固定的外盖帽的排放口固定的连接器,盖帽体通过连接器可弹性地被挤压在弹性开启/关闭部分中,挤压时内部输送通路开启。采用本发明的燃料箱即使燃料箱急剧摇摆或倾斜于其侧面也可以连续而平稳地提供燃料。

From the calculation of two different similarity measures—Pearson correlation coefficient and Spearman correlation coefficient, we found that about 94 percent of gene expression regulatory pathways are correlatively expressed in more than 4(including 4) sets of expression profile data, and it presents additional evidence for the correlation between gene function and its expression in the view of gene expression regulatory pathways.

通过Pearson相关系数和Spearman相关系数两种相似性测度的分析,我们发现有94%(15条)的基因表达调控通路内的基因在大于等于4套的表达谱数据中是共表达的,以上结果从基因表达调控通路的角度,证实了基因功能与基因表达之间存在着一定的相关性。

The one or more cells include a cell body defining an interior vell cavity, a flow path in the cell cavity through which particulate material and fluid flow, an electroactive zone within the cell cavity, and a fluid mechanic device adjacent or within the flow path capable of filling the electroactive zone or maintaining the electroactive zone in a constantly full or maximum electroactivity condition.

该一个或多个电池包括一个能构成内部电池腔的电池本体、一个位于该电池腔中供微粒材料与流体在其中流动的流动通路、一个位于该电池腔中的电活性区和一个流体力学设备,该设备邻近该流体流动通路或在该流体流动通路之内,它能为该电活性区充料或使该电活性区保持在恒定充满或电活性最强的状态。

To understand the basic properties, underlying mechanisms and functions of the short-term synaptic plasticity of thalamocortical visual pathway, we combined in vivo field potential recording, focal drug application technique and neuron models, to explore the short-tem synaptic plasticity of rat major thalamocortical visual pathway (from lateral geniculate nucleus to primary visual cortex) and extrageniculate pathway (from lateral posterior nucleus to primary visual cortex), as well as the role of short-term depression in the neuronal correlated firing detection.

我们结合在位场电位记录、局部加药和神经模型等方法,对不同刺激模式下大鼠丘脑皮层主要视觉通路(外侧膝状体到初级视皮层)和非主要视觉通路(膝体外通路:丘脑侧后核到初级视皮层)的短时程突触可塑性,以及短时程抑制作用对神经元同步活动检测的作用做了研究,试图了解视觉丘脑皮层突触传递短时程可塑性的基本特性、神经机制和功能。

The method of determining the paths based on backtracking method according to the network is introduced.

针对该网络给出了基于回溯法的通路的确定方法,进而给出了通路的可靠度的计算公式,最后给出了由通路的可靠度计算系统可靠度的计算公式。

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The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0,0.4,0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗,测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

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Have a good policy environment, real estate, secondary and tertiary markets can develop more rapidly and improved.

有一个良好的政策环境,房地产,二级和三级市场的发展更加迅速改善。