通路

Inhibition of this pathway results in development of antigen-specific unresponsiveness and clonal anergy.

阻断该通路可以导致抗原特异性的免疫耐受和克隆不应答状态。

The recurrent tumours are highly aneuploid and have varied activation of pro-proliferative pathways.

复发的肿瘤具有高度的异倍体，促增生通路中有不同程度活化。

Furthormore, xNorrin can not activate canonical Wnt signaling in the endomesoderm, suggesting additional mechanisms to restrict xNorrin activity in the ectoderm besides of its RNA localization in the animal pole..

进一步的体内实验表明，xNorrin协同xFrizzled4及xLrp5/6只能在外胚层激活经典Wnt信号通路，而在内中胚层中这种活性则很低，提示除了其RNA定位在动物极细胞之外，还存在着另外一种分子机制将xNorrin的活性限制在背部外胚层。

Objective To study the effect of alcohol extract of Pilose Antler on long-term potentiation in hippocampal CA1 region.

目的 研究鹿茸醇提物对海马CA3区Schaffer侧枝－CA1区通路长时程增强的影响。

Methylation of CpG islands in the promoters induces gene silencing. The multiple tumor suppressor gene P16, located at chromosome 9p21, regulating normal proliferation of cells with a functional unit constituting of p16, cyclin D1 and pRb together. Methylation of P16 gene has been detected in several lymphocytic and plasmacytic malignancies such as lymphoma, acute lymphocytic leukemia and multiple myeloma and shows relationships with the pathogenesis of these diseases. Application of demethylation agents or arsenical to refresh the gene functions will be expected to be a new treatment for hemopoietic malignancies.

基因启动子区CpG岛甲基化常导致基因沉默。P16基因是一定位于9p21的多种肿瘤抑制基因，通过pl6INK4Acyclin D1-PRb通路维持机体细胞的有序增殖。P16基因甲基化在淋巴瘤、急性淋巴细胞性白血病、多发性骨髓瘤等多种淋巴细胞浆细胞肿瘤中被检测到，并与疾病的发生、发展存在一定关系，应用甲基化抑制因子或砷剂去甲基化治疗，恢复基因功能可望成为血液恶性肿瘤治疗的一种新手段。

AUDIO: a sound board with 8-bit, 11.025-kHz sampling and 22.05-kHz playback; a synthesizer capable of playing eight notes simultaneously using five different sounds; a mixer to combine CD audio, sampling, and synth; a microphone input; and MIDI in, out, and thruports.

音频功能：一块8位的、11.025kHz取样和22.05kHz回放的声卡；能同时放8个使用5种不同音色的音律的合成器；能把光盘音频、取样和合成声音混合起来的混声器；麦克风输入；MIDI输入、输出和通路。

AUDIO: A sound board with 8-bit, 11.025-KHz sampling and 22.05-KHz playback; a synthesizer capable of playing eight notes simultaneously using five different sounds; a mixer to combine CD audio, sampling, and synth; a microphone

声频功能：一块8位的、11.025KHZ取样和22.05KHZ放声卡；能放出8个同时使用五种不同音色的音律的合成器；把光盘声频、取样和合成声音混合起来的混声器；麦克风输入；MIDI输入、输出和通路。

Objective:To investigate the expression and significance of p38 mitogenactivated protein kinase in autogenous vein graft.

目的：研究丝裂原活化蛋白激酶p38MAPK信号传导通路在自体移植静脉中的表达。

In the incidence and development of cancer, both out of tumor cell cycle control and autophagy change are closely related to the pathway.

在肿瘤的发生发展中，该通路与肿瘤细胞周期失控和自噬等方面有着紧密的内在联系。

The levels of DAG were investigated with radioenzymatic assay, thin-layer chromatography and autoradiography.

上述信号通路的变化效应，可被anti-CD40MAb阻断，这就进一步证实，rCD40L引起的DAG-PKC途径的激活是通过CD40而起作用的。

The reasons of iron ions content overproof in grade Ⅱ desalting water system,such as variation water quality,contamination of regenerant , operation adjustment of pretreatment system and switching operation of bed were discussed.

对二级脱盐水系统中铁离子含量超标的原因，如来水水质发生波动、再生剂受到污染、预处理系统操作调整、床体运行切换等进行了论述。

You were hired to drum up new business, so go and do it.

公司雇你招徕新业务，你就做你的事好了。