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We tested the effect of this ventilatory strategy on arterial oxygenation (Pao2) in patients undergoing laparoscopic bariatric surgery.

我们测试这种通气策略对於进行腹腔镜减肥手术患者的动脉氧合(PaO2)的影响。

There were no ventilatory effects caused by FF or placebo.

FF 和安慰剂对於通气没有作用。

There were no ventilatory effects caused by FF or placebo.

FF和安慰剂对于通气没有作用。

Over the past decade, advances in the ventilatory management of acute lung injury and ARDS have improved outcomes; however, until recently the search for other therapies has been less fruitful.

在过去10年急性肺损伤和ARDS机械通气治疗中的进展已经改善了预后。然而直到现在其他治疗的研究成果还比较少。

However, morphine caused a dose-dependent central depression during the hypercarbic ventilatory response and a mild depression of hypoxic ventilatory response.

然而,吗啡对於心肌肥大和低氧通气时的中枢抑制作用是剂量依赖性的。

Keywords chronic obstructive pulmonary disease; breathing pattern ;ventilatory efficiency;exercise performance

慢性阻塞性肺疾病;呼吸模式;通气效率;运动耐力

Objective To investigate the changes of T helper cellsubsets and relationship to the relative cytokines,serum total IgE,eosinophil count and ventilatory function in asthmatic patients.

目的 分析哮喘患者辅助性T淋巴细胞亚群平衡的变化及与相关细胞因子、血清总IgE、外周血嗜酸细胞及肺通气功能的相关关系。

Ketamine attenuates VILI in asthma rats in part because of probably inhibiting TNF-α, IL-6 and NO content in lung tissues.

氯胺酮可抑制TNF-α、IL-6及NO 的释放,从而对哮喘大鼠机械通气所致肺损伤起到保护作用。

Methods Both in vitro and in vivo models of ventilator-induced lung injury were used. Alveolar epithelial cells were stretched in vitro to mimic the lung injury in VILI. Rats were ventilated at large tidal volume to produce ventilator-induced lung injury in vivo. A total of 23 inflammatory cytokines were screened with micro gene array in stretched alveolar epithelial cells.

方法通过呼吸机诱导肺损伤的体内及体外模型,将分离的肺泡上皮细胞于体外拉长,利用基因微阵列技术分析并筛选出上调的炎性细胞因子,之后给予大鼠呼吸机机械通气,留取血清标本,测量这些细胞因子在血清中是否上调。

(1) Oxidative/antioxidative reactions, inflammatory reactions, apoptosis in lung are involved in the pathogenesis of HILI;(2) ABX, rHuEPO have protective effects on HILI respectively;(3) Hyperoxia can increase VILI in rats, but has little effects with low tidal volume mechanical ventilation.

结论(1)氧化抗氧化失衡,炎症反应,肺内细胞凋亡参与了高氧所致成年大鼠肺损伤的过程;(2)ABX通过抗炎、抗氧化、抑制细胞凋亡作用对成年大鼠高氧肺损伤具有保护作用;rHuEPO通过抗炎、抗氧化、抑制细胞凋亡及一定程度的抗纤维化作用对成年大鼠高氧肺损伤具有保护作用;(3)高浓度氧能明显加重大鼠通气机所致肺损伤,而高浓度氧对小潮气量通气影响较小。

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