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The typical apoptotic morphological features appeared in MUTZ-1 cells treated with 4mmol/L VPA for 72hours. Pyknosis of cells and nuclei, disintegration of nuclear chromatin and apoptotic body could be observed by light microscopy. Aggregation and margination of nuclear chromatin, concentration of plasm, increment of density and chromatin mass of irregular size could be observed by transmission electronmicroscope. The flow cytometric analysis indicated that the VPA could induce cell apoptosis, apoptosis rate increased in dose-dependent manner, ratio of cells at G0/G1 phase increased and ratio of cells at S phase decreased in dose-dependent manner, the cells were arrested at G0/G1 phase.

结果显示:VPA对MUTZ-1细胞的生长抑制作用呈现时间和剂量依赖性;经4mmol/LVPA处理MUTZ-1细胞72小时后,细胞呈现典型的凋亡形态特征,光学显微镜下可见凋亡细胞胞体固缩、核固缩、核碎裂及凋亡小体;透射电子显微镜下可见凋亡细胞核染色质边集、胞浆浓缩、密度增加,胞装内大小不规则的染色质团块;流式细胞术结果表明,细胞凋亡率随着VPA浓度的增加而逐步增高,G0/G1期细胞比例随着VPA浓度的增加而逐渐增多,S期细胞比例逐渐减低,细胞被阻滞在G0/G1期。

At the same time,3D display technique become a mainstream while image display technique maturate gradually.

同时随着图像显示技术的逐渐成熟,3D显示已经逐渐地成为游戏显示技术的主流。

Chinese furniture generally transformed from with emphasis on decoration to function and from mortise and tenon joint to KD construction.

中国家具逐渐实现了从重装饰的传统家具向简洁明快的现代家具,从传统的卯榫结构逐渐向现代板式结构,从传统材料向现代工业材料的过渡。

The multifold developments of modern logo design in idea,form,way of expression,usage of media were discussed.

计算机的广泛应用,互联网络的逐渐普及,信息高速公路的建立,使一个拥有60多亿人口的世界逐渐变成了一个"地球村"[1]。

Barnard says the basis of Christie's success is "the way she structures her books on a pattern of progressive mystification and progressive enlightenment".

巴纳德认为,克里斯蒂成功的基础在于"她构思小说是以逐渐神秘莫测而后又逐渐柳暗花明的方式"。

The level of nervation≥81mmHg,the rate of sicken of coronary heart disease was 9.73%.

当SBP逐渐增高,舒张压逐渐下降,冠心病发病率也增加(P<0.01)。

The results as follows:(1)The decrepit rules of Lycoris leaves were: the senescence of all leaves incarnated that they turned yellow from outside to inside; to the single leaves, the main type of senescence was that it was from tip to the edge gradually, and then went to middle nervation and to the base of leave finally. There was affinity between temperature and the senescence of lycoris longituba.

具体结果如下:(1)长筒石蒜叶片衰老形态的规律为:整株长筒石蒜叶片衰老主要是从外轮叶片逐渐向内轮叶片变黄;单个叶片的衰老主要类型是从叶尖开始逐渐沿着叶片边缘向叶中脉到叶的基部。

The length and number of apophysis was different, furthermore, neurofibril of immune-positive neuron of nNOS shows brown pinch-and-swell form and distributes interlacedly. We can draw

随着年龄增长,大脑皮质nNOS阳性神经元的密度、突起数、最长突起长度逐渐减小,而胞体截面积却逐渐增加,这些指标到了老年变化极显著P

The increase of ganglion volume mainly lied in growth of neurons and increasing of nerve fibers and neuroglia cells, but not lied in marked increase of neurons in number.

山羊胎儿脊神经节于胚胎第6周就已形成,但此时节内神经元形态不清晰,至第8周,节内神经元形态逐渐清晰,节内神经纤维数量少;随着胚胎发育,节内神经元数量并不显著增加,而是节细胞之间神经纤维及胶质细胞的增多和神经元个体的增长,从而使神经节的体积逐渐增大。

Histological structures of bursas of Fabricius were observed at the different developmental stages from chicken embryoes to chickens. The results were as follows. The bursa of Fabricius began to develop on the 13th day of post-hatching and its cell aggregated into the nodosity clique underneath the epithelium mucosae. On the 15th day of post-hatching, those cell cliques were surrounded by the flat epithelium and formed the basic structure of folliculus lymphaticus. The number of lymphocytes in the folliculus lymphaticus increased gradually, and the medulla and cortex of a majority of folliculus were not discriminated obviously. Until on the 7th day for chickens, the medulla and cortex of folliculus formed completely and the number of folliculus increased significantly. From 21 to 35 days old, the folliculus lymphaticus transformed from polygon into rectangle. Mucosa epithelial cells increased gradually and their cytoblasts arranged compactly into aline in the basilar part on the 35th day.

本研究观察了从鸡胚到出壳后的不同生长发育阶段法氏囊的组织结构,结果表明:胚胎13日龄时,法氏囊开始发育,粘膜上皮下形成结节状细胞集团;胚胎15日龄,聚集的细胞集团形成初始的淋巴滤泡;胚胎18日龄到出壳后1日龄,滤泡内淋巴细胞数量增多,多数滤泡髓质和皮质界限仍不明显;7日龄雏鸡法氏囊髓质皮质分界清晰,滤泡数量显著增多;21日龄到35日龄,滤泡由多边形逐渐转变成长方形;在35日龄时,粘膜上皮细胞逐渐增多,排列紧密,细胞核紧密排列成直线位于基底部。

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