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Under the optimized conditions, in-situ-generated N,N -dioxide from the corresponding amide (10 mol%) and m-CPBA (20 mol%) retained the same asymmetric catalytic activity and enantioselectivity, and most of the aromatic,α,β-unsaturated, heterocyclic, aliphatic and steric hindrance ketones could be converted into the corresponding cyanohydrin trimethylsilyl ethers in up to 99% yield and 93% ee.

底物扩展证明,该有机小分子催化体系对芳香酮、杂芳香酮、脂肪酮、位阻酮以及α,β-不饱和酮都具有优良的手性诱导能力,收率高达99%,对映选择性达93%ee。

Under the suitable conditions of reaction temperature 170℃, 1.5 MPa air and reaction time 6 h, the conversion of cyclohexane and the total selectivity of cyclohexanone and cyclohexanol were 5.39% and 88.7% respectively.

在反应温度170℃,空气压力1.5 MPa,反应时间6 h的优化条件下,环己烷转化率与酮醇总选择性分别为5.39%和88.7%。

Cyclohexane conversion of 33.7%,selectivity to cyclohexanone and cyclohexanol of 97.2%,cyclohexan...

在70℃和n(C6H12)∶n(H2O2)=1∶2条件下,采用两次加入过氧化氢的方式,环己烷转化率为33.7%,酮醇总选择性97.2%,n∶n=1.99,过氧化氢利用率37.1%。

It was found that manganese porphyrin had the highest activity, and a maximum 15.4% of cyclohexane conversion and 93.9% selectivity of cyclohexanone and cyclohexanol could be obtained under the suitable conditions.

结果发现,锰卟啉催化活性最好,在适宜反应条件下,环己烷转化率高达15.4%,环己酮和环己醇的总选择性约为93.9%。

Cyclohexanone yield of 85% and selectivity to cyclohexanone of nearly 100% were attained over the catalyst prepared under optimum condition.

在优化条件下制得的催化剂用於环己醇脱氢时,环己酮产品收率达85%,选择性近100%。

The easy recovery of chiral auxiliary, good selectivity and high yield of this reaction make it a potential method in the synthesis of multifunctional optically active cyclopropane derivatives.

手性硫叶立德控制的高对映选择性合成多取代烯基环丙烷衍生物。

Methods: We used virus proliferation assay cell viability assay to evaluate the proliferation and cytolysis selectivity of CNHK500. And we used Western-blot to confirm the expression of adenovirus CNHK500 E1A and E1B in cancer and normal cells.

行病毒增殖实验和细胞生长抑制实验,验证CNHK500选择性复制和杀伤能力;Western blot检测腺病毒E1A和E1B在细胞中的表达。

Antitumor efficacy of replication-competent adenovirus CNHK500 in vivo was associated with increased dosage of CNHK500. Conclusions: The results prove that CNHK500 has highly proliferation selectivity and potent cytolysis effect on breast cancer.

肿瘤选择性增殖腺病毒CNHK500可选择性在端粒酶阳性的乳腺癌细胞中复制,并产生体内外杀伤作用。

Objective: To determine the potency of QN-2013, a derivative of quinoxaline 1,4-N-oxide, as a hypoxia-selective cytotoxin or a radiosensitizer.

目的:检验和评价喹喔啉双氮氧化物衍生物QN-2013的选择性乏氧细胞毒性和放射增敏作用。

The most common RNA editing is mediated by ADAR(Adenosine deaminases that act on RNA),which could change adenosines to inosines via deamination reaction.

基因复制、RNA编辑与选择性剪切是一个基因产生多种蛋白质的重要途径。

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