退行的

Furthermore, abnormal morphology, shrinkage and reduced density of dendritic spines and defects in LTP were observed in brains of the patients suffering from mental retardation and neurodegenerative diseases; many mutant genes found from these patients encode component proteins of signal transduction for neuronal plasticity. These studies on synaptic plasticity would certainly promote making the effective prevention and treatment procedures for mental and neurodegenerative diseases.

此外，在精神迟滞性疾病和神经退行性疾病患者脑内记录到异常的LTP，并发现神经元的树突棘数量减少，形态上产生畸变或萎缩，同时发现，产生突变的基因大多编码调节突触可塑性的信号通路蛋白，故突触可塑性研究也将促进精神和神经疾病的预防和治疗。

The typical pathological characteristics of SPTs may result from gradual degenerative changes induced anoxemia in some SPT's areas. The heterogeneity of SPTs on different antibody markers showed that the SPTs may be originated from pancreatic embryonic stem cells, and result from immature differentiation of the pluripotential stem cells during pancreatic genesis.

SPT典型病理特征是由于肿瘤组织不同区域相对缺血、缺氧所造成的退行性变的结果，SPT表达多种组织来源的抗原，反映其可能来源于胰腺干细胞及与其发育密切相关的胚胎神经嵴的神经前体细胞，且在发育过程中发生分化不成熟的结果。

BACKGROUND: Extract of astragalus mongholicus has good effects on antioxidization and oxygen free radical scavenge. Bone marrow mesenchymal stem cells have multiple directional differentiation potential and superiority of autologous transplantation. This can provide a new way for treating neurodegenerative diseases.

背景：黄芪提取物有较好的抗氧化、清除氧自由基的作用，加之骨髓间充质干细胞的多向分化潜能及其自体移植的优越性，可能为神经退行性疾病的治疗提供新的方式。

Bhat and his team of MUSC Neuroscientists tested their hypothesis that high cholesterol, resulting from either diet or genetic disposition, would intensify the brain's inflammatory response and spur amyloid generation that would, in turn, lead to the neurodegeneration and dementia characteristic of Alzheimer's disease.

他们的研究工作验证了这一假设：即不管是饮食引起的或者遗传因素造成的高胆固醇都会加剧大脑的炎症反应，并刺激淀粉样蛋白的产生，逐步引起神经退行性病变并出现阿尔茨海默病的痴呆特征。

Although there is fair evidence that articial disc replacement is similarly effective compared to fusion for single level degenerative disc disease and that an interspinous spacer device is superior to nonsurgical therapy for 1- or 2-level spinal stenosis with symptoms relieved with forward exion, insufcient evidence exists to judge longterm benets or harms.

尽管已有相当的证据证明人工椎间盘置换治疗单节段脊柱退变疾病具有和融合手术类似的疗效，也有相当的证据证明棘突间支架治疗1～2个节段伴间歇性跛行的椎管狭窄的疗效优于非手术治疗，但以上都缺乏长期随访的证据。

The aim of our study was to analyse the interdependence of inflammation, neurodegeneration and disease progression in various multiple sclerosis stages in relation to lesional activity and clinical course, with a particular focus on progressive multiple sclerosis.

我们的研究目的是，在与病灶活动性及临床病程相关的多发性硬化症的不同阶段，分析炎症、神经退行性病变和疾病发展间相互依赖的关系，尤其侧重于对多发性硬化症进展期的研究。

The cell in acidic situation presented a degenerative chang-ment,such as an increased lipid drop and empty cavity in the cell plasma,a py-knotic nuclei,the dilatation of the endoplasmic reticulum and Golgi saccules,mi-tochondrial swelling the number of ribose decrease,and the ribose dissociated inthe plasma,a lot of swallowing cavity,the fibric material decreased accompany-ing with the acid being stronger.

随培养基pH逐渐下降，上述过程因受酸性阻抑而延缓，细胞增殖速度也受影响，处于酸性环境中的软骨细胞呈退行性变化，表现为细胞浆内脂质颗粒与小泡增多、细胞核皱缩、核仁浓染、内质网线粒体膨胀、核糖体数目减少，且与粗面内质网结合的少，游离在胞浆中的多。

Expandable cage is an effective tool on treating degenerated lumber disease. Excellent operative technique and appropriate choice of cages is the key point for a successful treatment.

可扩张型cage是治疗退行性腰椎疾病的有效方法，良好的手术技巧和选择合适的cage是手术成功的必要条件。

Increased expression of MMPs in RA has been repeatedly reported, and elevated levels of several MMPs have been detected in synovial membrane, synovial fluid, and serum from RA patients as compared with healthy controls or patients with degenerative joint disease.

在RA患者中MMPs表达升高已屡见报道，同健康人或是关节退行性变的病人相比，RA患者的滑膜组织，滑膜液，以及血中，几种MMPs的水平明显升高。

ABSTRACT Osteoarthritis is a degenerative joint disease characterized by the progressive erosion of articular cartilage as well as the thickening of subchondral bone. Both extracellular matrix damage and severe loss of chondrocytes in the articular cartilage participate in the process.

骨关节炎是以关节软骨进行性破坏及软骨下骨增生为特征的关节退行性病变，软骨基质的破坏以及软骨细胞的大量丧失参与了发病过程，在骨关节炎软骨组织中软骨细胞呈现过度凋亡的状态，凋亡在细胞丧失过程中发挥着重要作用。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐