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Methods: Rat models of chronic renal failure were made by cut 5/6 kindney or fed with feedingstuff which contains adenine(0.75%) for 4 weeks. Experimental treatment was applied by giving Yi Shen Granule and the curative effect of Yi Shen Granule on ongoing pathological changes of CRF was studied. According to the data of CRF rats in weight, water wastage, hemanalysis(RBC、HGB、HCT、MCV、MCH), urinalysis(volume, specific gravity, pH, proteinuria), blood serum analysis(BUN、Cre、ALB、TP), kidney weight coefficient and kidney morphology ( the grade of expansile renal tubule and the diameter of glomerulus ),the pharmacological effect of Yi Shen Granule could be ascertained.

实验选用0.75%腺嘌呤饲喂法致大鼠慢性肾衰模型和5/6肾切除法致大鼠肾衰模型,考察益肾颗粒对慢性肾功能衰竭进行性病变的影响,以造模动物一般状况观察、血液学指标包括红细胞计数、血红蛋白、红细胞压积、平均红细胞体积、平均红细胞血红蛋白(RBC、HGB、HCT、MCV、MCH),尿液指标(尿量、比重SG、pH值、尿蛋白)、血清生化学指标包括尿素氮、肌酐、白蛋白、总蛋白(BUN、Cre、ALB、TP)、脏器解剖和病理观察指标(肾小管扩张分级评分和肾小球径长)做为判定依据。

The progressive muscular dystrophy is the human phenotype blemish caused by injured DNA. It is compatible with an autosomal dominant inheritance and it has penetrance and expressivity.

结论进行性肌营养不良是由DNA损伤引起的人类表型缺陷;该病症符合常染色体显性遗传;该病的发生具有一定的外显率和表现度。

Parkinsons disease is a neurodegenerative disease which mostly occurs in the extrapyramidal system of middle or old age .

帕金森病是主要发生在中老年人锥体外系统的进行性神经变性疾病。

CBD appears to be closely related to another, less rare, sporadic extrapyramidal degeneratie disorder named Progresie Supranuclear Palsy .

CBD的发生是与另一个稍多见的散发的锥体外系变性疾病——进行性核上性麻痹密切相关联的。

The key part of beta-amyloid is its residue of 25-35 〓, which can aggregate into fibril in vivo and in vitro.

AD是一进行性神经退行性变,它的确切病因目前还不清楚,β淀粉样肽(β-amyloid,Aβ)的增加已被广泛接受为中枢病因性过程,所有致AD的已知突变都伴随有Aβ的大量产生。

New type of chronic and progressing filum terminale traction model of TCS was constructed and traction was removed after different times.

建立新型TCS慢性进行性终丝牵拉动物模型,进行不同时问的牵拉后解除牵拉。

Results All these infants were characterized by progressive flaccid paralysis in limbs.

结果 婴儿型脊髓性肌萎缩症的主要临床特征为出生后进行性加重的四肢弛缓性瘫痪。

"There are 32 million potential recipients in the United States alone. Merck stands to make $11.5 billion from this one immunization," Dr. Lex said. However, there are some political hurdles to overcome."It is opposed by religious leaders" on the grounds that vaccinating their young daughters would give them the green light to engage in sexual activity, he said — an argument he disagrees with.

Lex医师表示,单在美国就有3,200万潜在的疫苗接受者,制造该疫苗的默克药厂预估可以获利115亿美金,不过,还有一些政治上的困难有待克服,此疫苗受到宗教领袖反对,他们认为对年轻女孩注射该疫苗会让她们认为可以安全进行性行为,但Lex医师对此不表同意。

This is associated with chronic airways inflammation and structural remodeling, including loss of alveolar walls, and goblet cell metaplasia with mucus hypersecretion.

COPD患者的肺功能进行性下降,只有部分可逆,这与慢性气道炎症和气道结构重塑有关,包括肺泡壁的丧失,杯状细胞增生和粘液腺高分泌状态。

C1 ~ 2 injury most of the patients died immediately, C2 ~ 4 segments with phrenic nerve center, and more injured after a diaphragm and other respiratory muscle paralysis, patients have the sexual performance of breathing difficulties, damage on the plane following the limbs of motor neuron Is not completely paralyzed.

上颈髓损伤时,常有颈枕部疼痛,颈部运动受限。c1~2损伤时病人大多立即死亡,C2~4节段内有膈神经中枢,伤后多出现膈肌和其他呼吸肌麻痹,病人表现有进行性呼吸困难,损伤平面以下四肢上运动神经元性不完全瘫痪。

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