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Time constants do not increase but the weights of the fittings concentration de pendently enhance as the external Ba2+ concentration augments. So the inac tivati on becomes faster and faster as the external Ba2+ concentration increases. Time constants decrease and the weights of the fittings concentration dependently enh ance as the external Ba2+ concentration augments when external Ba2+ concentratio n (10 or 100 μmol/L) is higher. So the inactivation becomes faster and faster. It is showed that Ba2+ can go deeper in IRK1-T from the surface of the ch annel a s external Ba2+ concentration increases. CONCLUSION: Two diffe rent mechanisms for external Ba2+ blocking exist.

三级指数拟合表明:细胞外Ba2+低浓度(1和3 μmol/L)时,Ba2+与K+相互竞争同一结合位点,随着Ba2+浓度的增加,时间常数不增加但拟合的权数却浓度依赖性增加,所以失活过程随Ba2+浓度的增加越来越快;细胞外Ba2+高浓度(10和100 μmol/L)时,时间常数随Ba2+浓度的增加而减少,拟合的权数却浓度依赖性减少,失活过程也越来越快,说明Ba2+作用位点由通道的表面部位进入通道更深的地方。

Time constants do not increase but the weights of the fittings concentration de pendently enhance as the external Ba2+ concentration augments. So the inac tivati on becomes faster and faster as the external Ba2+ concentration increases. Time constants decrease and the weights of the fittings concentration dependently enh ance as the external Ba2+ concentration augments when external Ba2+ concentratio n (10 or 100 μmol/L) is higher. So the inactivation becomes faster and faster. It is showed that Ba2+ can go deeper in IRK1-T from the surface of the ch annel a s external Ba2+ concentration increases. CONCLUSION: Two diffe rent mechanisms for external Ba2+ blocking exist.

三级指数拟合表明:情绪细胞外Ba2+低浓度(1和3 μmol/L)时,Ba2+与K+相互竞争同一结合位点,随着Ba2+浓度的增加,时间常数不增加但拟合的权数却浓度依赖性增加,所以失活过程随Ba2+浓度的增加越来越快;情绪细胞外Ba2+高浓度(10和100 μmol/L)时,时间常数随Ba2+浓度的增加而减少,拟合的权数却浓度依赖性减少,失活过程也越来越快,说明Ba2+作用位点由通道的表面部位进入通道更深的地方。

Our results showed that the RnR was localized in the perinuclear zone and plasma membrane of the MCs.

本文旨在观察RnR在体外培养的大鼠肾小球系膜细胞(mesangial cells, MCs)和肾脏中是否表达,及其表达的细胞部位,并用RnR的多肽阻断剂肾素原&柄区肽&(handle region peptide, HRP)与RnR结合后观察受体复合物进入细胞的过程与定位。

This is how Mila and Oa have ascended in and out of cancer 3 times in their ascent to date; portions of their grid work failed to be rewoven to enough of an extent to hold the proper body temperature in certain regions of the form.

这是Mila和Oa在至今为止的提升中,是如何3次提升进入又超越癌症的过程,他们的部分晶格层未能充足重编到一个能在身体特定部位持有合适体温的程度。

During the study, we firstly discover that every internal cone locates 1/4-1/5 of setal lumen, which is different with that of seawater shrimps; new setae extend into the old setal lumens and end the old setal internal cones.

在本次研究中,首次发现在日本沼虾蜕皮间期刚毛锥的形成位置大约为刚毛腔的1/4-1/5,与海水虾显著不同;新刚毛尖端进入旧刚毛的刚毛腔并终止于旧刚毛的刚毛锥部位。

Thus, these younger children will be learning about parts of the body and getting prepped for feelings they may have when they reach puberty.

因此,这些更年幼的孩子将会学习有关身体部位的知识,及为进入青春期会产生的情绪做好准备。

HCV particles are formed by "bud mutation" of HCV in the cytoplasmic vesicles of B-lymphocytes.

病毒在感染细胞胞质空泡部位合成和组装,以芽生方式进入胞质空泡内形成病毒颗粒。

The proteins they make can enter the cisternae for transport to other parts of the cell or for secretion via the GOLGI APPARATUS.

此处产生的蛋白质可以直接进入扁平囊进行修饰而后输送到细胞的其他部位,或送到高尔基体进一步加工再被分泌。

Phagocytic microglia release cytokines and cytotoxins that regulate the survival of astrocytes and neurons in culture.

酒精进入神经系统后可对各种细胞产生直接毒性作用,包括减少大脑某些部位神经元细胞的数目和破坏神经元与神经胶质细胞之间的正常关系。

ResultsThrough a large number of the literature investigations,in the medicinal guides,some chemical constituents such as Platycodosides,3H-ligustrazine and aromatics,etc were found to have their own selectivity and the ability to actively enter the targetable sites, similar to the active target-tropism functions of primer, promoter, transmitter, mediator, transductor and transporter, etc.

结果经过大量的文献调研,发现引经中药中的某些化学成分如桔梗皂苷类、川芎嗪和芳香烃类等许多活性成分均有各自的主动选择性,能主动进入靶点部位,类似于引物、启动子、递质、介质、介导体、转导子、转运体等主动靶向性载体的功能。

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