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It is 712818 digits long and enters The Largest Known Primes Database ( http://primes.utm.edu/primes/) ranked 1st for Woodall primes and 25th overall.

这个质数有 712818 位十进位,是迄今为止发现的最大的 Woodall 质数,也是迄今为止发现的第 25 大的质数。

1 The prime is 606279 digits long and enters The Largest Known Primes Database ( http://primes.utm.edu/primes/) ranked 1st for Woodall primes and 37th overall.

这个质数有 606292 位十进位,是迄今为止发现的最大的 Woodall 质数,也是迄今为止发现的第 37 大的质数。

Meta-analyses showed that the response rate of TP (topotecan + cisplatin) regimen had no significant difference compared with EP regimen (etoposide + cisplatin) with OR 0.83 and 95%CI 0.63 to 1.09, but myelo-suppression such as leucopenia and thrombopenia was more severe with TP regimen; the response rate of monotherapy with topotecan was similar with that of CE (carboplatin + etoposide) regimen with OR 0.59 and 95%CI 0.22 to 1.60; the response rate of TEP (topotecan + etoposide + cisplatin) regimen was comparable with that of EP regimen with OR 1.37 and 95%CI 0.82 to –2.28, but myelosuppression and anemia were more severe with TEP regimen; the response rate with OR 0.97 and 95%CI 0.60 to –1.57, median time to progression with WMD –2.32 and 95%CI –5.72 to 1.09 and median survival time with WMD –1.65 and 95%CI –7.13 to 3.83 of IV topotecan were similar to those of oral topotecan, while neutropenia was more severe with IV topotecan.

Meta分析结果表明,TP 方案与EP方案的反应率相似 [OR 0.83, 95%CI (0.63,1.09)],但具有相对高的致血小板下降的骨髓毒性;单药拓朴替康与CE方案的反应率相似 [OR 0.59, 95%CI (0.22,1.60)];TEP方案(拓扑替康+足叶乙甙+顺铂)与EP方案的反应率相似 [OR 1.37, 95%CI (0.82,2.28)],TEP方案致化疗后重度白细胞下降、重度血小板下降、重度血红蛋白下降均高于EP方案;口服拓扑替康与静脉滴注拓扑替康的化疗后反应率 [OR 0.97, 95%CI (0.60,1.57)]、中位疾病进展期 [WMD –2.32, 95%CI (–5.72, 1.09)]、中位生存期 [WMD –1.65, 95%CI (–7.13,3.83)] 相似,口服拓扑替康化疗后重度中性粒细胞下降明显低于静脉滴注拓扑替康。

Meta-analysis based on included studies showed that response rate of TP regimen has no statistic significance compared with EP regimen[OR0.83,95%CI(0.63-1.090)],but myelo-suppression such as leucopenia and thrombopenia is more severe; response rate of single topotecan has no statistic significance compared with CE regimen[OR0.59,95%CI(0.22-1.60)]; response rate of TEP regimen has no statistic significance compared with EP regimen [OR1.37, 95%CI(0.82-2.28)], but myelo-suppression such as leucopenia, thrombopenia and anemia is more severe; response rate of IV topotecan has no statistic significance compared with Oral topotecan[OR0.97, 95%CI(0.60-1.57)],so as median time to progression[WMD-2.32, 95%CI(-5.72,1.09)] and median survival time[WMD-1.65, 95%CI(-7.13,3.83)],while neutropenia is more sever in IV topotecan than Oral topotecan.

分析表明,TP方案与EP方案的反应率相似[OR0.83,95%CI(0.63-1.090)],但具有相对高的致白细胞和血小板下降的骨髓毒性;单药拓扑替康与CE方案的反应率相似[OR0.59,95%CI(0.22-1.60)];TEP方案与EP方案的反应率相似[OR1.37,95%CI(0.82-2.28)],TEP方案致化疗后重度白细胞下降、重度血小板下降、重度血红蛋白下降均高于EP方案;口服拓扑替康与静脉滴注拓扑替康的化疗后反应率[OR0.97,95%CI(0.60-1.57)]、中位疾病进展期[WMD-2.32,95%CI(-5.72,1.09)]、中位生存期[WMD-1.65,95%CI(-7.13,3.83)]相似,口服拓扑替康化疗后重度中性粒细胞下降明显低于静脉滴注拓扑替康。

A man ran into a railway carriage, shouting vexedly, a lady fainted in the next carriage. Who has some whisky?

& 一位男子跑进车厢,着急地嚷嚷:&隔壁车厢里有一位太太晕过去了,谁带了威士忌?

The Cafe of the simple inn where they stayed was the meeting place of the notabilities of the little city; the Sindaco, the avvocato, the doctor, and a few others; and among them they noticed a beautiful, slim, talkative old man, with bright black eyes and snow-white hair — tall and straight and still with the figure of a youth, although the waiter told them with pride that the Conte was molto vecchio — would in fact be eightey in the following year.

他们住进了一家简陋的旅馆。旅馆的餐厅是小城名流云聚之地。有市长,律师,医生,还有其他的一些人。在这些人之中,有一位英俊健谈的高个老人引起了他们的注意。他有一双乌黑的眼睛,头发雪白,高大挺直的身板,像年轻人一样。然而,餐厅的服务生却有些自豪地告诉他们,这位伯爵年事已高,来年就有八十高龄了。

It will also apply the basic endowment insurance, basic hospitalization insurance, working injury insurance, procreating insurance, unemployment insurance for the new employees.

公司为每一位合格的应聘者提供有竞争力的薪水及完善的福利制度,对每一位新进员工承办养老保险、基本医疗保险、工伤保险、生育保险、失业保险。

It will also apply the basic endowment insurance, basic hospitalization insurance, working injury insurance, procreating insurance, unemployment insurance and housing accumulating fund for the new employees.

公司为每一位合格的应聘者提供有竞争力的薪水及完善的福利制度,对每一位新进员工承办养老保险、基本医疗保险、工伤保险、生育保险、失业保险及住房公积金。

Melwani's son, Roshan, ushers a big-waisted American into a fitting room while a blazered old brigadier pops in to pick up an order for his nephew.

麦文浩的儿子Roshan正在将一位腰很粗的美国人带进更衣间,而一位年迈的陆军少将正为他的侄子下订单。

At last, it"s studied the consistency of unsigned ones complement addition with bit-wise exclusive-OR and addition modulo 2". The formula of consistency probability is proposed.

随后,本文研究了进位返加运算与逐位模2加运算及模2~n加运算的相容性问题,给出了其相容概率的计算公式。

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然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

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