还原性

Asymmetric borane reduction of prochiral ketones is a good process to the synthesis of enantiomerically enriched secondary alcohols.

硼烷对前手性酮的不对称还原是合成手性仲醇的重要方法。

Herein we mainly discuss the design of four series of chialβ-amino alcohols and their application to the asymmetric borane reduction ofprochiral ketones.

本论文主要设计合成了四个系列的手性氨基醇类的催化剂，研究了它们在硼烷对前手性酮的不对称还原反应中的应用。

All the prepared compounds were characterized by 〓H NMR、〓P NMR and elemental analysis. The catalytic activity of each prepared chiral phosphorus compound in the borane reduction of prochiral ketones was studied.

对每一种手性磷化合物，考察了其作为配体催化剂在潜手性酮的不对称硼烷还原反应中的催化效果，讨论了影响不对称诱导的各种因素。

3A series of C_2-symmetric chiralβ-amino alcoholsⅢ-6 andⅢ-10were synthesized in several steps from natural amino acids,and applied in the asymmetric borane reduction of prochiral ketones.The catalytic activity ofⅢ-6 was better thanⅢ-10.

3以天然氨基酸为起始原料，经过简单的几步反应合成了开链冠醚类C_2-对称的手性β-氨基醇Ⅲ-6以及Ⅲ-10，将其应用于硼烷对前手性酮的不对称还原反应中，含有脯氨醇结构单元Ⅲ-6的催化效果要好于由其他氨基酸衍生的Ⅲ-10，THF为溶剂，回流，催化量为10 mol%时，最高得到85%的ee值。

S-1-phenylethanol was obtained in up to 19%ee in toluene at 0℃.(4)A series of C_2-symmetric chiralβ-amino alcoholsⅣ-5were synthesized in several steps from natural amino acid L-proline,and applied in the asymmetric borane reduction of prochiral ketones.

4以天然L-脯氨酸为起始原料，经过几步转化合成了以萘环为母体的C_2-对称的手性β-氨基醇Ⅳ-5，将其应用于硼烷对前手性酮的不对称还原反应中，同样，我们也观测到温度影(来源：Ac1BC论文网www.abclunwen.com)响产物构型的现象。

Asymmetric catalytic activity of chiral spiroborate esters,- or-1,1′-bi-2-naphthoxyboric acid-proline anhydride [-1 or-1], toward borane reduction of prochiral imine s has been ob- served.

手性螺硼酸酯-或-1，1'-联-2-萘酚硼酸--脯氨酸酐[-1或-1]对前手性亚胺硼烷还原的不对称催化活性被观察到。

METHODS: The rhBMP-2,expressed in Escherichia coli, was washed by Triton X- 100 and further purified by DEAE chromatography.The inclusion bodies were resolved in 8 mol/L urea, and were refolded and dimerized in the redox systems (reduced and oxidized glutathione). Finally, a one - step purification procedure based on the heparin affinity chromatography was implemented. The biological activity of purified rhBMP - 2 were tested by induction of the alkaline phosphatase activity in C2C12 cells.

在大肠杆菌中通过温度诱导表达重组人骨形成蛋白-2经过Triton X-100清洗之后，又通过DEAE离子交换层析纯化包涵体，包涵体在8 mol/L尿素变性溶解，在氧化-还原(还原型和氧化型谷胱甘肽)复性系统中，通过简单的稀释复性，通过肝素亲和层析一步纯化法纯化重组人骨形成蛋白-2，最后通过诱导C2C12细胞产生碱性磷酸酶检测重组人骨形成蛋白-2活性。

Chiral amines widely existed and play an important role in the nature. Catalytic asymmetric reduction of imines represents one of the most important methods for preparing chiral amines.

摘 要：手性胺化合物广泛存在于自然界中并扮演着重要的角色，亚胺的不对称催化还原反应是制备手性胺化合物的最直接有效的方法。

The asymmetric reduction of prochiral P-oxo ester, aromatic ketone and aliphatic ketone to its corresponding chiral alcohol by yeast cells were studied respectively in this work when ethyl 4-chloro-3-oxobutyrate, acetophenone and 2-octanone were as the model substrates.

本文以4-氯乙酰乙酸乙酯、苯乙酮和2-辛酮分别为β-羰基酯、芳香酮和脂肪酮的模型底物，研究了利用活性酵母细胞催化这三类前手性酮不对称还原合成相应手性醇的反应特性。

The effects of electronic and steric effect of substituted groups, the structure of chiral catalysts and chiral reagents and the reaction system on optical activity of products are summarized.

文章概述了芳香酮取代基的电子效应与空间效应、手性催化剂和手性试剂的结构、反应体系等对产物光学活性的影响，以及全细胞酶、分离酶等不同生物催化体系中芳香酮结构对产物光学活性的影响，并展望了不对称还原的研究及应用前景。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。