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运动神经元

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This was not seen in other patients with ALS whose upper motor neurone signs were not so manifest, nor in controls.

但上运动神经元症状体征不明显的ALS患者、正常人、其他神经疾病患者,却没有在T1、T2、PdWI这3像上均都出现高信号改变。

He is the first of four patients with spinal cord(6)injuries,muscular dystrophy(7), stroke or motor neurone(8) diseasetestingthe brain-to-movement system developed in Massachusetts.

四个分别患有脊髓损伤,肌肉失调,中风和运动神经元疾病的病人参与测试了这个在马萨诸塞州研制成功的大脑支配行动的装置。雷是他们中的第一个。

Especially for severe extremities disabled such as Injury to spinal cord, Motor neuron disease and so on, who are paralyses in a bed for a long-term. The people who have communication and action disabled, they couldn't do them well, so their lives are full of inconvenience. If they want to associate with the normal people, the most easy method is to make some word cards of reading. With these word cards to guess what he need from his health or psychology, such as the weathers turns cold,"cold","hot","wearing clothes" and so on, But it couldn't express all the thought from patients. Therefore, it often caused that we can't know what the patients want or their condition. It's too inconvenient for their lives.

尤其是重度肢体障碍患者,如脊髓损伤、运动神经元疾病患者等长期瘫痪在床的病人,对於沟通和行动障碍两者并存的患者而言,其日常生活起居处处充满著不便,一般与此类患者沟通最简单的方式就是制作一些简易读字卡,依著基本的身体或心理层面去推敲他的需要,如天气转凉了,「冷」「热」「穿衣服」等…,但这并不能完全表达患者的需求,因此常造成无法满足患者需求的情况,造成生活上非常的不方便。

The diagnosis of ALS was established clinically on the basis of the history and physical and electrophysiological examinations. In five patients (cases 1-5), the initial symptoms were spastic paraparesis.

21例ALS患者中有5例(病例1~5)首发症状为下肢痉挛性轻瘫,在病程进展过程中均出现上运动神经元症状体征,包括肌强直、腱反射亢进、Babinski征,尤以病例2、病例4的患者明显。

The diagnosis of ALS was established clinically on the basis of the history and physical and electrophysiological examinations. In five patients (cases 1-5), the initial symptoms were spastic paraparesis.

所有21名患者均依病史、体格检查、电生理检查临床确诊为ALS.21例ALS患者中有5例(病例1~5)首发症状为下肢痉挛性轻瘫,在病程进展过程中均出现上运动神经元症状体征,包括肌强直、腱反射亢进、Babinski征,尤以病例2、病例4的患者明显。

Cases 1-5 who presented with spastic paraparesis and other prominent upper motor neurone signs showed high signal on T1-weighted images in the centrum semiovale, corona radiata and posterior limb of the internal capsule which corresponded to the large myelinated fibres of the corticospinal tract Fig.

病例1~5患者表现为下肢痉挛性轻瘫和其他一些明显的上运动神经元症状体征,在T1像上于半卵圆中心、放射冠、内囊后肢处的皮质脊髓束大有髓纤维走行区均可见高信号病灶(图1),在T2、PdWI像上也可见自放射冠延伸至大脑脚的高信号病灶。

MMN should be differentiated from motor neuron disease and chronic inflammatory demyelinating polyneuropathy.

MMN应与运动神经元病和慢性炎性脱髓鞘性多发性神经根神经病鉴别。

After sciatic nerve lesion 3 days, Schwann cells and other non-neuronal elements, begin to proliferate and express a great deal of neurotrophic factors incloding NT3, showing that NT3 may be transported retrogradely to neuronal soma, resulting in strong immunoreactivity.

损伤后3天,以雪旺细胞为主的非神经细胞开始大量增殖,雪旺细胞表达大量神经营养因子包括NT3,并逆向转运到达运动神经元胞体,这也导致免疫反应性的增强。

It is reported that retrogradely tansported Ⅰ〓-NTs, CNTF to ventral horn cells greatly increased and can be blocked by excess non-labelled NTs, CNTF, suggesting that the increased transport of NTFs were mediated via the receptors.

有文献报道,坐骨神经损伤后外源性CNTF可诱导脊髓运动神经元CNTF受体的高表达。

The experiments are conducted on adult Sprague-Dawley rats.The author investigates the discharge patterns of the non-motorneurons in the facial nucleus of rats and the alteration of respiratory rhythm to electrical stimulation of the facial nucleus in which the motor neurons are retrogradely degenarated.

实验选用健康成年SD大鼠,观察大鼠面神经核内的非运动神经元的放电样式以及电刺激面神经核对呼吸节律的影响,以探讨面神经核是否参与呼吸调节。

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