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The staining of F-actin in the ischemia reperfusion group was decreased significantly (P.05) compared with the normal control group. There was a marked loss of canalicular microvilli and distension of canalicular lumen in the ischemia reperfusion group. The staining of F-actin in the LA group was significantly increased than those in the I/R group (P.05). Conclusions: Ischemia reperfusion induces an disruption of bile canalicular F-actin microfilaments and a loss of microvilli. Alpha-lipoic acid can protect bile canalicular F-actin microfilaments against IRI.

肝脏I/R可造成胆小管F-actin微丝破坏、微绒毛丧失,导致胆小管收缩减弱,胆汁排泄功能受损,这可能是大鼠肝脏I/ R后缺血型胆道病变发生的主要机制;α-硫辛酸通过清除氧自由基,降低脂质过氧化反应,调节细胞内氧化剂-抗氧化剂的含量,保护胆小管F-actin微丝结构免遭缺血再灌注损伤破坏,进而预防和治疗缺血型胆道病变。

Comparing with conventional air handling process, the liquid desiccant air-conditioning system can dehumidify air without cooling down to its dew point. Meanwhile, counteraction cooling and heating can be avoided, which usually happened in conventional air handling process and led to huge energy waste. In addition, during the air handling process no condensation water separates out of the air in the liquid desiccant air-conditioning system, thus, avoid fungi thrives in moist environment of traditional air handling process. Not only being applied in dehumidification process in summer, the system can also realize humidification process in winter conditions efficiently.

与传统的空气处理方式相比,采用溶液式空气处理方式,具有如下优越性:取消了冷凝水表面,消除了霉菌等生长所需的潮湿环境;既可以对空气除湿处理,又能实现冬季对于空气的加湿处理过程;可方便调节处理后的相对湿度,不再是常规冷凝除湿方式中接近100%相对湿度的出口空气参数;避免了常规空调系统冷凝除湿后温度过低还需再热带来的冷热抵消问题;可以充分利用低品位能源如太阳能和废热实现溶液再生,节省系统电耗。

In addition, your baby's mouth small and shallow, swallowing reflex function is not perfect, will not be used to regulate the movements of swallowing saliva, so when the little saliva or baby happy, laugh and play, you may be unable to secrete saliva from All swallowing it, and diffuse over embankment, the outflow of extraoral.

再加上宝宝的口腔小而浅,吞咽反射功能还不健全,不会用吞咽动作来调节口水,所以当唾液分泌稍多或是宝宝高兴、嬉笑时,可能就会因无法将分泌出来的口水全部吞咽下去,而漫过大堤,流出口外。

Mercapto derivatives yield persulfide products that are potential sources of sulfane sulfur, which may modify protein function by reacting at important cysteinyl domains.

疏基衍生物产生的过硫化物是硫烷硫的潜在来源,后者可通过与重要的半胱氨酸区域反应来调节蛋白功能。

Mercapto deriaties yield persulfide products that are potential sources of sulfane sulfur, which may modify protein function by reacting at important cysteinyl domains.

疏基衍生物产生的过硫化物是硫烷硫的潜在来源,后者可通过与重要的半胱氨酸区域反应来调节蛋白功能。

Results:(1) FSN can inhibit secondary joints swelling and multi-arthritis evidently, improve the whole condition of rats; at the same time, it can also lighten the synovial inflammation and hyperplasia of lesion joints distinctly, and prevent the joint cartilage and bone from destruction; the collective efficiency of FSN is better than TWP.(2) FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th / Ts and Thl / Th2 cells balance in peripheral blood, restrain exorbitant TNF- a ? IL-1 produced by PM O , thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF- a mRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflamination and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue,reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage.Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果:(1)FSN有明显的抗炎作用,可显著抑制AA大鼠足跖肿胀与多关节炎,改善大鼠的全身情况,同时明显减轻病变关节滑膜炎症与增生,防止关节软骨及骨质的破坏,其综合作用优于TWP;(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常,纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱,抑制大鼠PHφ过高的TNF-α、IL-1分泌,而发挥抗炎和免疫调节作用;(3)在病变关节局部,FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达,降低滑膜组织中NF-kB表达,并增加凋亡蛋白酶Caspase-3表达,从而抑制滑膜的炎症与增殖;(4)FSN还可下调滑膜组织中VEGF表达,减少血管新生,由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀;(5)FSN的上述作用皆呈现一定的量效依赖关系,高剂量组作用优于低剂量组。

FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th/Ts and Th1/Th2 cells balance in peripheral blood, restrain exorbitant TNF-α、IL-1 produced by PMφ, thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF-αmRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflammation and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue, reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage. Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果:(1)FSN有明显的抗炎作用,可显著抑制AA大鼠足跖肿胀与多关节炎,改善大鼠的全身情况,同时明显减轻病变关节滑膜炎症与增生,防止关节软骨及骨质的破坏,其综合作用优于TWP;(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常,纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱,抑制大鼠PMφ过高的TNF-α、IL-1分泌,而发挥抗炎和免疫调节作用;(3)在病变关节局部,FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达,降低滑膜组织中NF-kB表达,并增加凋亡蛋白酶Caspase-3表达,从而抑制滑膜的炎症与增殖;(4)FSN还可下调滑膜组织中VEGF表达,减少血管新生,由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀;(5)FSN的上述作用皆呈现一定的量效依赖关系,高剂量组作用优于低剂量组。

Qingnao drop pilula can alleciate histomorphology lesion of hippocampus when occurring acute multi-infarction, to turn slower MARCKS mRNA expression, may play a neuroprotective effect role through accommodating PKC-MARCKS signal transduction system.

清脑滴丸可以减轻急性脑缺血时海马组织损伤,下调MARCKS mRNA的过高表达,其机制可能是通过调节PKC-MARCKS信号转导系统而起到神经保护作用。

Comparative study on the change of lipid peroxidation product and activities of regulatable enzymes by irradiation of N + ion beam and 60Co γ-rays .

顾月华,罗江虹,罗建平,等。N+离子束和60Co γ射线辐照引起脂质过氧化产物及调节酶活性变化的比较研究,核技术,1999,22(8):44-48。

Using volatile acid and alkali to regulate the pH of pressed juice from bamboo shell,saltless Fraction Ⅰand Fraction Ⅱwere got separately.the residue of squeezed banboo shell was used as paper making material and medium for cultivation mushroom.

采用挥发性酸和碱调节鲜笋壳压榨液 pH值,分别获得无盐Fraction Ⅰ和fraction Ⅱ;其压榨后的蒲渣作为造纸原料和栽培食用菌的基质;对分离Fraction Ⅰ和Fraction Ⅱ后的汁液,加入Fe2 +并超滤浓缩,经硫酸铵盐析和丙酮分级后,进行CM 2 2纤维素离子交换柱层析,以 pH5 。2乙酸钠分级洗脱,获得RZ为 3 。0以上的高纯竹笋过氧氧化物酶。

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In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国,慢性酒精中毒,肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题,你可以随时联系我。

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很漂亮,不过停机坪更迷人。那人俏皮地答道。