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The index case was a 5-month-old infant girl who had anisocoria from 4 weeks of age. One hour after 1% apraclonidine hydrochloride was instilled in each eye, there was blanching of the periocular skin, and the parents reported that the infant was excessively drowsy. Two hours after receiving apraclonidine, the infant was taken to the emergency department for lethargy and unresponsiveness, with bradycardia (84 beats/min), shallow respiration (40 breaths/min), and blood pressure 115/85 mm Hg. Oxygen saturation was 80% but improved rapidly to 100% when oxygen was given via a face mask. Eight hours after receiving apraclonidine, the infant had returned to normal.

指标案例是一名5个月大的女婴,她从4周大时就有瞳孔大小不等的状况;在1%的apraclonidine氯化氢徐徐滴点她的双眼后1个小时,眼眶周边的皮肤即变白,而她的家长表示她变得非常嗜睡;在使用apraclonidine 2个小时之后,该名女婴因嗜睡和无应答性,以及心搏过慢(每分钟84下)、呼吸浅弱(每分钟40次)以及血压115/85 mm Hg等症候而被送进急诊室;血氧饱和度原先为80%,在面罩给氧后迅速回复到100%,在使用apraclonidine 8个小时后,该名女婴终于回复健康状态。

The index case was a 5-month-old infant girl who had anisocoria from 4 weeks of age. One hour after 1% apraclonidine hydrochloride was instilled in each eye, there was blanching of the periocular skin, and the parents reported that the infant was excessively drowsy. Two hours after receiving apraclonidine, the infant was taken to the emergency department for lethargy and unresponsiveness, with bradycardia (84 beats/min), shallow respiration (40 breaths/min), and blood pressure 115/85 mm Hg. Oxygen saturation was 80% but improved rapidly to 100% when oxygen was given via a face mask. Eight hours after receiving apraclonidine, the infant had returned to normal.

指标案例是一名5个月大的女婴,她从4周大时就有瞳孔大小不等的状况;在1%的apraclonidine氯化氢徐徐滴点她的双眼后1个小时,眼眶周边的皮肤即变白,而她的家长表示她变得非常嗜睡;在使用apraclonidine 2个小时之后,该名女婴因嗜睡和无应答性,以及心搏过慢(每分钟84下)、呼吸浅弱(每分钟40次)以及血压115/85 mm Hg等症候而被送进急诊室;血氧饱和度原先为80%,在面罩给氧后迅速回复到100%,在使用apraclonidine 8个小时后,该名女婴终於回复健康状态。

The polymerization reacts from the inverse emulsion . Selecting white oil as continuous medium , Span60 and TX-10 as the complex emulsifier , AM-01﹑(NH4)2S2O4 and NaHSO3 as new-type complex initiator , the copolymerization of dimethylamino ethyl acrylate methyl chloride/acrylamide was developed . The effects of the concentration of monomer﹑emulsifier and initiator﹑ temperature﹑reaction time and pH on the molecular weight﹑intrinsic viscostity﹑conversion ratio and cation degree of copolymer were studied .

以反相乳液为初始聚合体系,油酸失水山梨醇酯Span60和辛基酚聚氧乙烯醚TX-10构成复配乳化剂,白油为连续介质,AM-01、过硫酸铵和亚硫酸氢钠组成新型复合引发体系,进行丙烯酰胺/(2-甲基丙烯酰氧乙基)三甲基氯化铵的反相准微乳液共聚合,研究了单体浓度、乳化剂、反应温度、反应时间、pH等因素对聚合产品分子量、特性粘数、转化率及阳离子度的影响。

Changes of lipid hyperoxidation and amount of circulating endothelial cells under simulated weightlessness and factors that may influence these changes were observed in 3 groups of subjects (5 in each group) exposed to 17d -6° head down bed rest, HDBR+hypoxia and HDBR+qigong respectively.

为研究模拟失重、低氧、气功及其复合作用对人体脂质过氧化及循环内皮细胞含量的影响,受试者为15名19~21岁男性健康青年,分为单纯卧床组、卧床+低氧组和卧床+气功组进行了17d的头低位-6°卧床实验。

However, the forced expression of exogenous Smad3 did not rescue the inhibition of myogenic differentiation by hypoxia.

在研究过程中,我们发现在低氧抑制成肌细胞体外分化过程中Smad3蛋白的表达水平降低,然而,在C2C12细胞中过表达外源性的Smad3没有能够逆转低氧对成肌细胞分化的抑制作用。

N,N '- ditertbutyl nitroxyl radical, 2, 2,6,6- tetramethyl-4 - hydroxyl piperdinehy droxylamine and its nitroxyl radical, as inhibitors of the BPO- initiated copolymerization of styrene (M 1 ) with acrylonitrile (M2 ), at 60℃,has been studied.

研究了二叔丁基羟胺,二叔丁基氮氧自由基,2,2,6,6-四甲基-4-羟基哌啶羟胺和2,2,6,6-四甲基-4-羟基哌啶-1-氧自由基对过氧化苯甲酰60℃引发的苯乙烯(M1)-丙烯腈(M2)共聚合的阻聚行为。

Aimed at the over proof problem of dissolved oxygen in condensation water for 300 MW units, a great deal of tests have been made, this paper deals with the effects of feed water pump sealing water, seal steam heater drain water, overcool degree of condensation water , and condenser makeup water, and puts forward some effective improving measures.

针对某电厂300MW机组凝结水溶氧超标的问题,进行了大量的试验研究,提出了给水泵密封水、轴加疏水、凝结水过冷度以及凝汽器补水等对凝结水溶氧量的影响,并对此提出了一些行之有效的改进措施。

Based on a thorough analysis of the experimental results, a coupling mechanism of the catalytic selective oxidation and non-catalytic partial oxidation in which the surface adsorbed 〓 species and the lattice 〓 species take part synergically.

在全面分析实验结果的基础上,提出了一个由表面吸附氧种〓和晶格氧种〓协同参与的甲烷催化选择氧化与气相非催化部分氧化相耦合的反应机理,催化剂的参与既在表面开辟了生成〓和HCHO的新途径,又可将气相反应中的强氧化型物种转移到催化剂表面,形成有利于选择氧化的表面活性氧种,同时避免了气相中强氧化型物种浓度过高而导致选择氧化产物深度氧化。

Using tetrabutyl titanate and methyl methacrylateor 2-Hydroxyethylmethacrylate (HEMA as materials, methacryloxylpropyl trimethoxy siliane as coupling agent, HCl as catalyst, Poly-titania(PMMA-TiO2) nanocomposites and Poly-titania(PMMA-TiO2) nanocomposites were synthesized by sol-gel process.

以盐酸作为催化剂,将钛酸四丁酯水解制备二氧化钛(TiO2)溶胶;随后将所制备溶胶与甲基丙烯酸甲酯、硅烷偶联剂(γ-甲基丙烯酰氧丙基三甲氧基硅烷)相混合,以过氧化苯甲酰作为引发剂,经过聚合、缩合和溶胶-凝胶过程,制备了均匀透明的PMMA-TiO2纳米复合材料和PHEMA-TiO2纳米复合材料。

In this research, B2 gene of HCV was highly expressed as a fusion protein (Trx-B2) by cloning into pThioHisA, and induced specific anti-HCV antibody in higher titer than unmodified B2 protein after immunize mice or rabbit.The results showed antigen Trx-B2 has obvious immunogenicity and induced specific antibody,which might be able to serve as diagnosis HCV. Consequently, this PcAb of rabbit was used to coated Immulon plate, and a method of both antibodys sandwiching antigens was developed to detect 32 HCV positive serum and 32 nomal serum.Results show that ratio of positive are 87.5%and 43.75% respectively.

但缺点是该抗原所诱导的抗体滴度较低,可能是由于其分子量较小,所以本课题将人工合成的HCV复合多表位抗原基因B_2克隆到表达载体pThioHisA中,利用硫氧还蛋白融合方式对该抗原进行修饰,并在大肠杆菌中表达融合蛋白(Trx-B_2),纯化该蛋白后免疫小鼠及家兔,结果表明用硫氧还蛋白修饰后的融合蛋白免疫小鼠和家兔后,得到的抗体滴度均高于未经修饰过的复合多表位抗原合成肽所诱导的抗体滴度,并从免疫后的兔血清中提取IgG包被酶联板,利用双抗夹心法分别检测了32份HCV阳性血清和32份正常人的血清,结果阳性率分别为87.5%和43.75%,符合率为71.88%。

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