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Objective To study antianaphylaxis activities of myricetin.

摘要目的研究杨梅素的抗过敏作用。

These results indicate that the potent antianaphylaxis effect of myricetin may be associated with the inhibition of typeⅠand type Ⅳ allergic reaction.

杨梅素具有抗过敏作用,机制可能与抑制Ⅰ、Ⅳ型变态反应有关。

These results indicate that the potent antianaphylaxis effect of myricetin may be associated with the inhibition of typeⅠand type Ⅳ allergic reaction .

杨梅素具有抗过敏作用,机制可能与抑制Ⅰ、Ⅳ型变态反应有关。关键词杨梅素;抗过敏;被动皮肤过敏反应;瘙痒反应;迟发型超敏反应

Methods The antianaphylaxis activities of myricetin was measured by passive cutaneous anaphylaxis, dextran-induced itch and DNCB-induced delayed type hypersensitivity in mice,respectively.

采用小鼠同种、异种被动皮肤过敏反应、右旋糖酐致小鼠全身瘙痒反应和2,4-二硝基氯苯所致小鼠耳廓皮肤迟发型超敏反应实验,探讨杨梅素的抗过敏作用。

The first aim of this study is to clarify whether that polymorphisms of the genes that encode these enzymes associates with the TB drugs-induced adverse reactions. Furthermore, since tuberculosis patients are always administrated with multiple TB drugs, it is hard to distinguish which TB drug caused these adverse reactions.

本研究从结核药物过敏病患代谢酵素基因多型性方面探讨与结核药物过敏反应发生的相关性;此外,由於结核病患通常同时接受多种结核药物的治疗,导致难以判断是其中何种药物引起不良反应,本研究另一目标即为建立一T细胞体外培养系统,用於判断何种药物引起不良反应的产生。

Sheep embryo with high-purity,high-quality and high security features to extract the cells from the completion of the injection can be divided into three phases:-Using the most advanced chemical and biological equipment from sheep embryos to extract the liver activity of the protein and remove impurities,heat-sensitive eggs White matter and may result in allergic reactions of various types of risk factors-The adoption of advanced technology to extract the cells separated,thus the effectiveness of different cells,such as chest Gland cells,placental cells,liver cells and so on dozens of different types of-Using the most advanced technology to maintain the freeze-dried cells of live sheep-embryo for the first time the use of only afew hours to keep The cell activity,and now,with the continuous development of science and technology,after the extract ion of the cells have been able to keep to five years.

羊胚胎素具有高纯度、高品质和高安全性的特点,从细胞的提取到针剂的完成可分为三个阶段:-运用最先进的生化磁粉探伤仪,从小羊胚胎的肝脏中提取活性蛋白质,并去除杂质、热敏感蛋白质及可能导致过敏反应的各类危险因子-通过先进的技术对提取的活性细胞进行分离,从而得到具有不同功效的活性细胞,如胸腺细胞、胎盘细胞、肝脏细胞等几十种不同类型-采用目前最先进的冻干技术来保持细胞鲜活性,羊胚胎素在最初使用时只能保持几小时的细胞活性,而如今,随着科学技术的不断发展,提取后的细胞活性已经可以保持到5年。

A semisynthetic analogue of cephalosporin having a broad spectrum of antibiotic activity that is administered parenterally and used especially to treat systemic infections caused by susceptible microorganisms.

先锋霉素I,头孢霉菌素头孢菌素的一种半人工合成替代物,有广谱抗生性能,注射使用,尤其用于治疗由过敏微有机物体引起的系统感染到中国译典经典版本中查找关于semisynthetic的最新解释和例句。。。。

A single systemic injection of resiniferatoxin , an ultrapotent analog of capsaicin, produced a long-lasting, reversible blockade of adjuvant-induced thermal hyperalgesia and reduction of early edema in the adult rat. Depletion of mast cell granules in peripheral connective tissues with secretagogue compound 48/80 also reduced the hyperalgesia and early edema to some extent. Co-pretreatment with RTX and compound48/80 had the similar effects as that of RTX treated alone. After unilateral surgical sympathectomy, the thermal hyperalgasia and edema were both significantly enhanced.

成年鼠一次性注射辣椒素类似物resiniferatoxin后,长时程、可逆性阻断了CFA所致热痛过敏的发展并削弱了早期炎性水肿;用促脱颗粒剂compound48/80慢性耗竭外周结缔组织肥大细胞内分泌颗粒后,也部分削弱了热痛过敏及早期水肿的形成;RTX与compound48/80共同处理对热痛过敏及水肿有与RTX单独处理相近程度及时程的影响;单侧交感链切除显著易化了炎性热痛过敏及水肿。

ResultsPe Min Kam Wan, Lam Kam Sang Nasalin and Wo Chun Tong clearly inhibited PCA in mice and reduced histamine release from rat mast cells induced by compound 48/80. But,Sinuwell did not affect the PCA. In addition, the ethanol extracts from Senecio scandens, Selaginella tamariscina and Xanthium sibiricum significantly inhibited PCA in mice, but the extracts from Angelica dahurica, Magnolia liliflora and Cassia tora failed to affect it.

结果速效鼻敏感丸、林金生鼻敏清胶囊及和春堂鼻敏清片明显抑制小鼠异种被动皮肤过敏反应,减少compound 48/80诱导的组胺释放,而速效鼻敏素胶囊对被动皮肤过敏反应无明显影响;速效鼻敏感丸及和春堂鼻敏清片主要组成药物九里明、卷柏和苍耳子显著抑制小鼠异种被动皮肤过敏反应,而白芷、辛夷和决明子无明显作用。

It is mainly used for adjuvant treatment of high blood pressure; the most common use of rutaceae is treatment of allergies, which can slow down the speed that the mast cell releases histamine, while histamine is right the chemical substance causing general allergic reaction.

主要用於高血压辅助治疗;芸香素的最常见用途是治疗过敏,它可减缓肥大细胞释放组织胺的速度,而组织胺正是引起一般过敏反应的化学物质。

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