过大的

Commercial center in Nanjing, 20 plus sign "close hand-to-hand" is the result : some sign of operational difficulties. even started its suppliers purchase price; There are two located in the city center and north of the city of Nanjing, average daily sales were only 20 million and 15 million dollars of investment -- a sign of, the sales figures is tantamount to committing slow suicide.

在商业重镇南京，20多家大卖场"贴身肉搏"的结果就是：一些大卖场因经营困难，甚至开始拖欠供应商货款；有两家位于南京城北和城中的大卖场，日均销售分别只有20万元和15万元左右―――对一家投资过亿的大卖场来说，这样的销售数字无异于慢性自杀。

"It's as big or bigger than the largest plesiosaur ever found," Hurum said.

"这和我们已经发现过的最大的蛇颈龙一般大，甚至更大。"

Results:(1) FSN can inhibit secondary joints swelling and multi-arthritis evidently, improve the whole condition of rats; at the same time, it can also lighten the synovial inflammation and hyperplasia of lesion joints distinctly, and prevent the joint cartilage and bone from destruction; the collective efficiency of FSN is better than TWP.(2) FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th / Ts and Thl / Th2 cells balance in peripheral blood, restrain exorbitant TNF- a ? IL-1 produced by PM O , thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF- a mRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflamination and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue,reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage.Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果：(1)FSN有明显的抗炎作用，可显著抑制AA大鼠足跖肿胀与多关节炎，改善大鼠的全身情况，同时明显减轻病变关节滑膜炎症与增生，防止关节软骨及骨质的破坏，其综合作用优于TWP；(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常，纠正外周血中T细胞亚群Th／Ts及Th1／Th2平衡紊乱，抑制大鼠PHφ过高的TNF-α、IL-1分泌，而发挥抗炎和免疫调节作用；(3)在病变关节局部，FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达，降低滑膜组织中NF-kB表达，并增加凋亡蛋白酶Caspase-3表达，从而抑制滑膜的炎症与增殖；(4)FSN还可下调滑膜组织中VEGF表达，减少血管新生，由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀；(5)FSN的上述作用皆呈现一定的量效依赖关系，高剂量组作用优于低剂量组。

FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th/Ts and Th1/Th2 cells balance in peripheral blood, restrain exorbitant TNF-α、IL-1 produced by PMφ, thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF-αmRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflammation and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue, reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage. Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果：(1)FSN有明显的抗炎作用，可显著抑制AA大鼠足跖肿胀与多关节炎，改善大鼠的全身情况，同时明显减轻病变关节滑膜炎症与增生，防止关节软骨及骨质的破坏，其综合作用优于TWP；(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常，纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱，抑制大鼠PMφ过高的TNF-α、IL-1分泌，而发挥抗炎和免疫调节作用；(3)在病变关节局部，FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达，降低滑膜组织中NF-kB表达，并增加凋亡蛋白酶Caspase-3表达，从而抑制滑膜的炎症与增殖；(4)FSN还可下调滑膜组织中VEGF表达，减少血管新生，由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀；(5)FSN的上述作用皆呈现一定的量效依赖关系，高剂量组作用优于低剂量组。

Effective target point of nucleus accumbens located at its ventromedial part.

毁损灶体积过小，导致手术无效；毁损灶偏离有效靶点，或毁损体积过大，均可导致并发症的发生。

When there is excessive political mobilisation the political space becomes too big and the economic and social spaces are too small.

在发展中国家，民主往往造成国家经济和社会生活的过分政治化。国家过分政治动员，造成政治空间过大，经济和社会空间过小。

If too loose, floor contraction larger the cracks will appear, too tight, floor when inflated arch camber.

如果过松，地板收缩就会出现较大的缝隙，过紧，地板膨胀时就会起拱。

A heavy lace trimming made of twisted gold or silver threads.The centuries, the revolutions, which at least devastate with impartiality and grandeur, have been joined by a cloud of school architects, licensed, sworn, and bound by oath;defacing with the discernment and choice of bad taste, substituting the fussiness of Louis XV. for the Gothic lace, for the greater glory of the Parthenon.

数百年岁月和历次革命风云所造成的破坏，至少是没有偏心的，正大磊落的，然而接踵而至的那多如牛毛的各种流派建筑师，却都是特许的，宣过誓的，许过愿的，他们对低级趣味趋之若鹜，竭尽毁坏之能事，竟用路易十五时代菊苣纹饰去代替巴特农神庙里最大光轮上峨特式的花边饰带。

Have you been to the prairies in North America?

你去过北美洲的大草原吗？在这些教材中出现过。。。

This controller also can give timely warning of adnormal instancessuch as too big current or too small current and working of single tube.

控制器还具有出错监控功能，可对焊接过程中出现的异常情况（如电流值过大或过小及单管导通）进行及时报警处理。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。