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Results are as followed:1 Exposure of HELF cells to BP caused c-Jun activation,and increased the activity of MAPK,PI-3K,p53 and cyclin D1 pathway.2 BP-induced c-Jun activation was inhibited by dominant negative mutants of extracellular signal-regulated protein kinase or c-Jun NH_2-terminal kinase,but not by p38,impling that JNK and ERK pathways medicate c-Jun activation induced by BP.3 Overexpression of dominant-negative mutants PI-3K and Akt potently blocked phosphorylations of c-Jun and ERK,but not JNK in response to BP,suggesting that PI-3K/Akt pathway positively regulates BP-induced c-Jun activation through ERK.4 Inhibition of p53 by its chemical or molecular inhibitor markedly increased the phosphorylation levels of c-Jun,Akt and ERK upon BP stimulation,indicating that p53 negatively medicates BP-induced c-Jun activation through PI-3K/Akt/ERK pathway.5 The cell lines expressed TAM67 exhibits no significant affecting normal cell growth properties.6 TAM67 was able to significantly block G_1-S transition and subsequent cell proliferation,suggesting that c-Jun is essential for cell cycle alternations elicited by BP.7 Overexpression of TAM67 impaired BP-induced cyclin D1 activation,decreasing expression of E2F1 and pRb,indicating that c-Jun participates in the modulation of BP-induced activation of cyclin D1/pRb/E2F1 pathway.8 Stably expression of TAM67 led to the increases in the expression levels of p53 and p21,elevating phosphorylation level of p53,clearly indicating that c-Jun regulates p53/p21 pathway activation induced by BRCollectively,PI3K/Akt/ERK pathway mediated BP-induced c-Jun activation through p53-dependent mechanism.

结果显示：1BP刺激细胞可促进c-Jun活化，并伴随着MAPK、PI-3K、p53和cyclinD1通路各组成成分的活性增强。2利用MAPK通路的显性失活突变体分别阻断细胞外信号调节激酶和c-Jun氨基末端激酶活性，均可明显抑制BP诱导的c-Jun活化，但阻断p38活性对BP引起的c-Jun活化无明显影响，提示JNK和ERK通路参与调控BP诱导的c-Jun活化。3过表达PI-3K和Akt的显性失活突变体也可显著抑制BP诱导的c-Jun活化，并降低磷酸化ERK的表达水平，但对磷酸化JNK的表达水平无明显影响，说明PI-3K/Akt通路通过ERK正性调控了BP诱导的c-Jun活化。4p53的化学/分子抑制剂能使BP作用的细胞内c-Jun活性明显增加，并同时诱导Akt和ERK的磷酸化水平的升高，表明p53可通过PI-3K/Akt/ERK通路对BP诱导的c-Jun活化进行负性调控。5随后观察转染细胞的生长情况，发现TAM67对细胞正常生长和形态无明显影响。6稳定表达TAM67可有效抑制BP诱导的S期细胞数的增加，提示c-Jun在BP致细胞周期改变的过程中发挥了重要作用。7TAM67过表达能够抑制BP诱导的cyclin D1活化，降低磷酸化Rb以及E2F1蛋白表达水平，表明c-Jun参与调控BP诱导的cyclin D1/Rb/E2F1通路的活化。8过表达TAM67可使BP刺激的细胞中p53、p21总蛋白以及p53磷酸化的表达水平明显升高，可见c-Jun也参与调控BP诱导的p53/p21通路活化。

Increasing the irradiant above the specified level is not recommended because of the danger of overheating, and there is presently no indication that attempting to accelerate the test in this way gives results that correlate with equipment response under natural solar radiation conditions.

处于过热引起的危险，并不建议对测试对象施加过强的光照。过强光照对设备引起的反应同自然界的阳光辐射并没有关联。

The results show that the toughness of over-heated zone increased greatly because of austenite film lying in lathy martensite and a few ferrite.The toughness of fine grained zone decreased due to many factors,such as acicular martensite,a small quantity of austenite film,carbide separation and so on.

结果表明，10Ni8CrMoV这一新型钢种的模拟焊接热影响区的过热区和细晶区表现出与绝大多数材料完全相反的规律，过热区存在少量的铁素体组织，马氏体板条束之间形成了一定量的奥氏体薄膜，这些韧度相的存在使得过热区的冲击韧度与基体相比有了较大的提高；细晶区部位奥氏体含量很少，细小的板条马氏体端部呈针状特征造成应力集中，易于诱发裂纹。

Watching tv,listening to the radio.besides the news,i mainly watche the balls mathes ,espcially the football.

我养过鸟，养过狗，现在还养猫；集邮、搜集书画我都着过迷；看电视、听广播，除新闻之外，主要是看球，特别是足球。

Over the next 14 years he would serve the Reds as both a player and a manager, notching 172 times in 515 games and picking up a whole host of silverware.

在随后的14年中，他在利物浦既当过球员也当过主教练，在515球场中打入172球，捧起过无数奖杯。

Typical results of the limits of superheat and su p er-depressurization for methane and propane are given,and the critical liquid st orage conditions that can lead to limits of super depressurization are analysed.

以 甲烷和丙烷为例给出了过热极限和过减压极限的典型计算结果，分析了可能使液体达到过减压极限的储存条件。

From the analysis,it can be found that improper L and R will led to overlarge grounding residual current and voltage in the arc-suppression process,being not helpful.

由分析过程可以得出，电感值和电阻值的大小选择不合适，将会在灭弧过程中产生过大的接地残流或后期过高的过电压水平，不利于电弧的快速熄灭。

Short-circuit,overload,resistance of line or cable's connection overlarge,which cause line overheat,making sparkle and electric arc.

文摘：介绍了配电线路在运行中发生短路、过负荷以及导线或电缆接头处接触电阻过大而引起导线过热、产生火花和电弧引起火灾事故的原因。

The laser-cladding layeron the alloy consists of matrix phase of over-saturation solid solution γ and complexhexagonal carbide M_7C_3. Under certain condition, with fast laser scanning speed, the oversaturation solubility of elements increases in γ, and the precipitation of the complexcarbide M_7C_3 decreases, so that the microhardness increases and the wear resistance de-creases. But at slower laser scanning speed, more complex carbide M_7C_3 may precipitate, andthe wear resistance may be improved. Therefore, it is believed that the principal factor in im-provement over wear resistance is the precipitation of carbide M_7C_3, while overmicrohardness is the over-saturation solubility of elements in matrix phase.

表明：(1)激光熔覆合金层是由过饱和的γ基体相和复杂的六方M_7C_3碳化物相所组成(2)在其他参数不变的情况下，随激光扫描速度的提高，γ基体相过饱和度增大，而析出的碳化物含量减少，因而合金层的硬度升高，耐磨性有所下降；而降低激光的扫描速度，碳化物M_7C_3析出增加，有利于提高合金层的耐磨性、因此碳化物M_7C_3析出量是提高耐磨性的主要因素，而增加基体相γ的过饱和度则是硬度提高的主要因素

Zn-La alloys increase the overpotential ofhydrogen evolution, Tafel slope 〓 and polarization, decrease the corrosion current density, inhibitthe corrosion of zinc electrode in alkaline solution, decrease anode Tafel slope 〓, promotedischarge reaction of zinc electrode, have higher passivation current density, inhibit thepassivation of zinc electrode, avoid the oversaturation of zincate in electrolyte, greatly increase〓 diffusion coefficient, decrease Tafel slope 〓, polarization and the overpotential of deposition,inhibit the dendrites formation and improve the electrodepostion of Zn.

实验结果表明，Zn-La合金电极显著改善了锌电极的各项电化学性能：提高析氢过电位、析氢过程Tafel斜率〓和极化，减小腐蚀电流密度，抑制锌电极在碱液中的腐蚀；降低阳极Tafel斜率〓，促进了锌电极的放电反应；具有较高的维钝电流密度，抑制锌电极的钝化；有效避免了溶液中锌酸盐的过饱和现象：使〓的扩散系数明显增大：降低Zn沉积过程的Tafel斜率〓、极化和沉积过电位，明显抑制锌枝晶的生长，改善了锌的电沉积性能。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。