辣椒素

Objective:To research the effect of capsicin on the NOS in rat facial skin, and to explore the analgesic mechanism of CAP in treating prosopalgia thereby.

目的：研究辣椒素对大鼠面部皮肤一氧化氮合酶阳性神经的影响，探讨CAP治疗三叉神经的镇痛机制。

Nerve endings are stimulated by capsaicin and release CGRP which has positive chronotropic response to cardiac muscle cells.

神经末梢受到辣椒素的刺激后，神经递质CGRP的释放对心肌细胞具有正性变时反应。5。

METHODS: Adults with chronic persistent cough (n = 25) and healthy controls (n = 11) were assessed by cough-specific quality of life questionnaire, extrathoracic airway hyperresponsiveness to hypertonic saline provocation, capsaicin cough reflex hypersensitivity, and fibreoptic laryngoscopy to assess PVCM.

对25名慢性持续咳嗽患者和11名健康志愿者进行咳嗽特异性生活质量问卷调查，并检测高渗盐溶液激发的胸腔外气道高反应性、辣椒素咳嗽反射超敏反应和纤维支气管镜来评价PVCM。

Half of the men received 1,000 micrograms of ultra purified capsaicin (an odorless, flavorless substance) directly into their wounds during surgery.

一半的男人收到1000个微克（ 1克），超高纯度辣椒素（一种无味， flavorless物质），直接到他们的伤口在手术中。

Capsaicin excites nociceptive afferent nerves to produce warmth when initially applied, but with repeated application it desensitizes unmyelinated nerve fibers to produce hypalgesia without also causing patients to experience a reddening or blistering.

最初辣椒素刺激疼痛传入神经产生温暖，但通过它的反复刺激，使无髓神经纤维不敏感，从而产生痛觉迟钝，也没有造成患者能够体验到发红或者起泡。

The effects of intrarenal artery injection of capsaicin on multi- and single-unit spontaneous discharges of renal afferent nerve fibers were investigated in anesthetized rabbits.

应用记录肾传入神经多单位和单位放电的方法，观察肾动脉内注射辣椒素对麻醉家兔肾神经传入纤维自发放电活动的影响。

RESULTS: The capsaicin receptor TRPV1 is a polymodal nociceptor exhibiting a dynamic threshold of activation that could be lowered under inflammatory conditions.

结果：辣椒素受体TRPV1是一种多模式伤害性感受器，具有可在炎性情况下降低的动态激活阈值，与此模式一致的是TRPV1敲除的小鼠缺乏炎症后热性痛觉过敏。

The removal effects of cpsaicin,sodium percarbonate,cupric sulfate and cupric glutamate on Alexandrium sp.

为了寻找新型有效的赤潮藻杀灭剂，对辣椒素、过碳酸钠、CuSO4、谷氨酸铜对亚历山大藻LC3的杀灭效果以及表面活性剂对谷氨酸铜杀藻的促进作用进行了研究。

OBJECTIVE To determine whether the protection of rutaecarpine against myocardial ischemia-reperfu-sion injury is related to the activation of capsaicin-sensitive sensory nerves in rats.

目的 观察吴茱萸次碱对大鼠心肌缺血再灌注损伤的保护作用是否与激活辣椒素敏感的感觉神经有关。

Calcitonin generelated peptidemediated depressor effect and inhibiting vascular hypertrophy of rutaecarpine in renovascular hypertensive rats. J Cardiovasc Pharmacol, 2007;

综合本研究结果和以往资料，在结状神经节和岩神经节内存在肽类和非肽类（IB4）两种不同的辣椒素敏感神经元亚群，说明VR1可能参与不同的内脏伤害性感觉信息的感受。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。