辅酶因子

A holoenzyme is the catalytically active form of the enzyme with its cofactor,whereas an apoenzyme is the protein part on its own.

全酶是酶与辅助因子一起形成的催化活性形式，而辅基酶本身的蛋白质部分。

Types of hydrogenase are reviewed,i ts applications have found its appli cations,such as biohydrogen production,wastewater treatment,prevention of microbial-induced corrosion,generation and regeneration of NADP cofactors.

介绍了氢化酶的类型，讨论了氢化酶在生物制氢、废水处理、预防微生物腐蚀、NADP辅因子的产生及其再生等生物技术领域中的应用。

PIAS proteins play roles mainly through two mechanisms: acting as SUMO E3 ligases to promote modifications of some transcriptional factors and cofactors, especially sumoylation, and to regulate their transcriptional activation; acting as structural proteins to offer platforms for protein-protein interactions and to promote the abstraction and recruitment of other regulators in the cellular signal pathway complexes or gene transcriptional complexes, companied by the subnuclear location of target proteins.

PIAS蛋白的调控机制主要有两种：一种是通过其自身所具有的SUMO(small ubiquitin-related modifiers)E3连接酶活性，促进对一些转录因子、转录辅因子的化学修饰，尤其是SUMO化修饰，从而调控它们的转录活性；另一种是作为构架蛋白，为蛋白质之间的相互作用提供平台，促进细胞信号通路复合物或基因转录复合物中其它调节蛋白的去除和募集，并涉及到靶蛋白的亚核定位。

Objective: To investigate the cellular signal transudation pathway of vascular smooth muscle cell proliferation and cytokins secretion stimulated by oxidized low density lipoprotein and insulin-like growth factor-1 (IGF-1) and the intervention effect of HMGcoA reductase inhibitor, atovastatin and immune supppressor, rapamycin.

目的：探讨氧化低密度脂蛋白，胰岛素样生长因子-1(IGF-1)促血管平滑肌细胞增殖及分泌功能改变的细胞内信号转导机制及三羟基三甲基戊二酰辅酶A抑制剂阿托伐他汀与免疫抑制剂雷帕霉素干预作用。

Objective: To investigate the cellular signal transudation pathway of vascular smooth muscle cell proliferation and cytokins secretion stimulated by oxidized low density lipoprotein and insulin-like growth factor-1(IGF-1) and the intervention effect of HMG-coA reductase inhibitor, atovastatin and immune supppressor .rapamycin.

目的：探讨氧化低密度脂蛋白，胰岛素样生长因子-1(IGF-1)促血管平滑肌细胞增殖及分泌功能改变的细胞内信号转导机制及三羟基三甲基戊二酰辅酶A抑制剂阿托伐他汀与免疫抑制剂雷帕霉素干预作用。

Histone acetyltransferase CBP/p300 remodels chromatin by acetylating histones resulting in open structure of chromatin and active transcription.

转录辅因子CBP／p300本身具有组蛋白乙酰转移酶活性，参与许多基因的转录调控过程。

Apoenzyme An ENZYME whose cofactor or prosthetic group has been removed (e.g. via dialysis) rendering it catalytically inactive. It is the protein part of a conjugate enzyme.

脱辅基酶蛋白：酶的辅助因子或辅基去除后剩下的没有催化活性的部分，是共轭酶的蛋白质部分。

Some elements of proteins,such as architectures, catalytic site of enzymes, coenzymes, cofactors, and short sequences and so on, is very conserved during evolution that can serve as molecular fossils to help infer the characters of primitive proteins on structures and functions.

蛋白质的某些性质，包括折叠类型、酶的催化位点、辅酶、辅因子以及部分短肽片段等，在进化过程中是非常保守的。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。