辅酶

First, the significant of co-factor InsP6 and center water in the mechanism of auxins are explored by docking; second, the experiments that compared with the docking rusults of two situations involving fully rigid and selective flexible of active residue of the receptor TIR1 illuminate that selective flexibility docking by AutoDock4 reports more rational results, so that, AutoDock4 dockings are implemented with TIR1-Auxins; third, AutoDock4 docking by TIR1-Auxins-Aux/IAA illuminates that auxin as a molecular glue enhances the interaction between TIR1 receptor and Aux/IAA substrate by the weak interactions, such as hydrogen bond and hydrophobic interaction, furthermore, the weak interactions between receptor protein and ligands greatly influence on auxin activity of auxin ligands.

首先， 通过分子对接计算研究辅酶InsP6以及中心水分子在生长素反应中的重要作用；其次，比较受体大分子完全刚性以及活性残基部分柔性的两种情况下的分子对接结果，说明AutoDock4实现了受体分子活性残基的部分柔性而使对接结果更加合理，进而使用AutoDock4方法对TIR1-Auxins体系进行对接计算；最后，对TIR1-Auxins-Aux/IAA体系进行分子对接计算，结果表明，生长素配体分子作为&分子胶水&直接与受体大分子TIR1以及底物多肽Aux/IAA形成强的弱相互作用，如氢键作用、疏水相互作用，促进了受体TIR1与Aux/IAA底物之间的结合，进而说明氢键作用和疏水相互作用等弱相互作用对于生长素分子的活性具有很大的影响。

Plus green tea extract, energising co-enzyme Q10 and soy isoflavones, which may help maintain elasticity to promote radiant skin.

加绿茶提取物，热情辅酶Q10的和大豆异黄酮，这可能有助于保持弹性，以促进容光焕发的皮肤。

The mitochondria presents several defense systems, of which the ubiquinone (Coenzyme Q10), which is one of the components of the respiratory chain and which has a significant antioxidant function acting upon membrane proteins.

线粒体具有几种防御系统，泛醌（辅酶Q10）是呼吸链的组成成分之一，在膜蛋白质上具有重要的抗氧化功能。

Ubidecarenone coenzyme Q_(10, Ubiquinone is an important electron transfer conmponent in respiratory chain.

辅酶Q_(10)Ubidecarenone，conezyme Q_(10，又名泛醌，是呼吸链中一种重要的递氢体。

With structure similar to that of vitamin K, Coenzyme Q10 also known as Ubiquinone 10 is a kind of fatsoluble quinone (C6H4O2), where "10" refers to the number of isoprenyl chemical subunits.

辅酶 Q10又名泛醌10，是一种脂溶性醌，其结构类似于维生素K，因其母核六位上的侧链——聚异戊烯基的聚合度为10而得名，是一种醌环类化合物。

In contrast, the 6 months therapy with pravastatin in combination with ubiquinone Q10 (60 mg daily) sharply decreased the LDL initial lipoperoxides level whereas during treatment with cerivastatin in combination with probucol (250 mg daily) the LDL lipoperoxides concentration was maintained on an invariable level.

方法与结果：维生素400mg/d治疗三个月未降低LDL氧化易感性；普罗布考250mg/d3-6个月治疗未改变血液脂质代谢参数，但显示了强抗氧化性；普伐他汀40mg/d或西立伐他汀0.4mg/d治疗6个月，体内脂质过氧化物大量聚集；普伐他汀和辅酶Q（60mg/d）联合用药能够大大降低LDL脂质过氧化水平；西立伐他汀与普罗布考（250mg/d）联用对LDL脂质过氧化水平无明显影响。

Part II: Synthesis of chiral sulfinyl NADH models. Three synthetic routes are adopted, i.e.

第二部分：手性亚砜类辅酶NADH模型物的合成。

This thesis is concerned with the synthesis of new chiral sulfinyl NADH models, whose key step is the synthsis of chiral R-3-pyridyl sulfoxides.

本论文的研究工作主要是合成新的手性亚砜类辅酶NADH模型物，工作重点在手性R基-3-吡啶基亚砜的合成上。

The lack of any diastereoselectivity for the formation ofβ-hydroxyketones with optically active sulfinyl analogue of NAD~+ model supports the radical mechanism proposed previously.

并将手性的亚砜类辅酶NAD~+模型物用于反应，没有得到立体选择性产物，验证了先前提出的自由基机理。

An efficient method for the selective hydrogenation of a series ofα,β-epoxyketones toβ-hydroxyketones using catalytic amount of two sulfinyl analogues of NAD~+ model compounds is reported.

利用两个亚砜类辅酶NAD~+模型物的催化反应，实现了α，β-环氧酮向β-羟基酮的高效转化。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。