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软骨肉瘤

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Methods: Immunohistochemical assay was used to detect the expression of COX-2 and Fas in 38 osteosarcoma tissues (38 cases) and 20 osteochondroma tissues (20 cases).

应用免疫组化SP法检测38例骨肉瘤组织、20例骨软骨瘤组织中COX-2和Fas的表达。

Methods vWF protein was examined using immunohis-tochemical SABC staining method in 54 cases of osteosarcoma and 10 cases of osteochondroma.

方法应用免疫组织化学SABC方法检测10例骨软骨瘤和54例骨肉瘤组织中的vWF表达情况。

Methods: The expression of OPG and OPGL in human osteosarcoma tissue, osteochondroma was detected by immunohistochemistry.

采用免疫组化方法研究骨肉瘤、骨软骨瘤中OPG、OPGL的表达并分析其差异性。

Methods PTEN and Caspase-3 were detected by S-P immunohistochemical method in 38 cases of paraffin-embedded section of osteosarcoma and 20 of osteochondroma.

方法用免疫组织化学方法检测PTEN和Caspase-3在38例骨肉瘤及20例骨软骨瘤中的表达。

Methods Expression of livin protein were detected by immunohistochemistry staining assay in 45 osteosarcoma cases and 30 osteochondroma cases.

采用免疫组织化学SABC法检测45例骨肉瘤、30例骨软骨瘤凋亡抑制蛋白Livin表达,并分析其与临床病理因素的关系。

Methods Skp2 protein and p27 protein were examined by using immunohistochemical SP staining method in 48 cases of osteosarcoma and 16 cases of osteochondroma.

用免疫组织化学SP法检测16例骨软骨瘤和48例骨肉瘤组织中Skp2和p27蛋白的表达情况。

Results Negative expression of Skp2 was detected in all osteochondroma. In contrast, it was detected in 43.75%(21/48)of osteosarcoma.

用免疫组织化学SP法检测16例骨软骨瘤和48例骨肉瘤组织中Skp2和p27蛋白的表达情况。

MATERIAL AND METHODS: By kept in archives 53 OS and osteochondroma specimens embedded in paraffine were chosen.

材料与方法:本实验选择存档中石蜡包埋通常型骨肉瘤标本53例,骨软骨瘤标本 20 例。

Results The expression of MMP-2 was high in OS,was low in osteochondroma,but the expression of TIMP-2 was reversed.

结果 MMP-2在骨肉瘤中高表达,在骨软骨瘤中低表达,而TIMP-2则相反。

When Fas and c-myc protein were coexpressed in cytoplasm, a strong positive sign appeared in highly differentiated osteosarcoma, fibrous dysplasia of bone and osteoplast of bone callus, a weak sign was found in low-differentiated tumour cells and fibroblasts.

Fas和c-myc蛋白胞浆内阳性,在骨肉瘤的高分化细胞(骨母细胞型和软骨细胞型瘤细胞)和骨化性纤维瘤、骨纤维结构不良、骨痂组织中骨母细胞呈强表达;而在低分化瘤细胞和纤维母细胞则呈弱表达。

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