软骨的

Current application for hip arthroscopy include management of labral tears, osteoplasty for femoroacetabular impingement, thermal capsulorrhaphy and capsular plication for subtle rotational instability and capsular laxity, lateral impact injury and chondral lesions, osteochondritis dissecans, ligamentum teres injuries, internal and external snapping hip, removal of loose bodies, synovial biopsy, subtotal synovectomy, synovial chondromatosis, infection, and certain cases of mild to moderate osteoarthritis with associated mechanical symptoms.

目前髋关节镜主要应用于盂唇撕裂的处理、股骨髋臼的撞击症的骨成形、隐匿性髋关节旋转不稳的热关节囊紧缩或关节囊皱折术，治疗软骨损伤、剥脱性骨软骨炎、圆韧带损伤、内源性或外源性弹响髋，清除游离体、滑膜活检、滑膜次全切、滑膜软骨瘤病、感染和某些伴有机械症状的轻度至中度骨性关节炎。

Objective: To establish a model of cultivating the rabbit chondral cells outside the body,observe the effect of Morida officinalis How polysaccharide on the proliferation andapoptosis on the level of cell and molecule and explore the mechanism of curing osteoarthritisby using Morinda officinalis How polysaccharide.

目的：建立体外培养兔软骨细胞的体系，应用体外培养的兔软骨细胞，在细胞和分子水平观察巴戟天多糖对软骨细胞增殖和凋亡的影响，探讨巴戟天多糖治疗骨性关节炎的机理。

This investigation include two parts: lThe primary culture, chondroblast induction and evaluation of MSC. 2The chondroblast cultured with compound porous materials PDLLA and PDLLA/chitosan.

第一部分人骨髓基质干细胞的原代分离、体外培养、成软骨诱导及鉴定目的：了解骨髓基质干细胞原代培养的特性及增殖能力，探讨轻度离心和化学限定培养基法诱导骨髓基质干细胞向成软骨方向分化的作用；为软骨组织工程提供足量、合适的种子细胞。

RESULTS: A substantial portion of knees with ROA were classified as having longitudinal cartilage thinning (28%) or thickening (20%) in at least one medial femorotibial subregion based on comparisons to longitudinal changes observed in healthy knees; only 5% showed both subregional thinning and thickening across medial subregions at the same time.

结果：基于在健康膝盖中所观察到的纵向变化，很大一部分ROA患者的膝盖软骨厚度的变化情况可分为两类：至少1个内侧股胫亚区的纵向软骨变薄（28%）或纵向软骨增厚（20％）；仅有5％同时在不同内侧亚区出现亚区变薄和增厚。

To study the biologicaleffect of pulsed electromagnetic fieldson the proliferation of Immunomagneticseparated human precartilaginous stem cellsin vitro.To establish immortalizedhuman precartilaginous stem cellsstrain and provided stable cell resource to studythe molecular mechanism of gene targeting on differentiation of PSCs.①The cells from the aborted fetus\'s metaphysis were digested by collagenase,the PSCs were isolated by magnetic-activated cell sorting,then were subculturedand amplified.

探讨体外分离、培养人前软骨干细胞的可行性，分析其表型特点；研究脉冲电磁场对免疫磁性细胞分选的人前软骨干细胞增殖的生物学影响；构建猿肾病毒40大T抗原基因(SV40Tag)介导的永生化人前软骨干细胞株，为下一步基因打靶研究其分化分子机制提供稳定的细胞来源。

Then we discussed the valuation of MRI in detecting cartilage abnormalities. 3. Creation and evaluation to the patellofemoral and tibiofemoral catilage degeneration modle Sixteen goats were used in this experiment.

关节镜下的按照Outerbridge软骨分级标准进行诊断，分析MRI分级和关节镜分级的相关性和SPIR/3D T1-FFE诊断软骨病变的敏感性及特异性，讨论MRI对髌股关节软骨病变诊断的价值。

The cells of the third stratum were typical mast cells without the tidal line in rat cartilage, cells which arranged into pillar with the distinct tidal line in rabbit cartilage, large irregular cells and coenocytes with the obvious tidal line in human cartilage.

在软骨损伤和骨关节炎的实验研究中，多数研究是以兔和大鼠为实验动物，而且大部分教科书中的软骨组织学结构是以兔的软骨进行描述的。

Construct PLXRN-IL-1Ra and PLXRN-IL-10 vector, lapine synoviocytes were first transduced in culture by retroviral infection. The genetically modified synovial cells were then transplanted by intra-articular injection into the knee joints, assay of joint lavages confirmed that the gene expression was not lost after 14 days of transfer. Knees receiving the hIL-1Ra had significantly reduced cartilage breakdown. Delivery of the hIL-10 was less effective, When both genes were used together, there was a greater inhibition of cartilage breakdown and a considerable reduction of cartilage matrix degradation.

构建PLXRN-IL-1Ra、PLXRN-IL-10逆转录病毒载体，体外感染同种异体原代滑膜细胞，接着将转染了外源基因的滑膜细胞行关节腔注射入创伤性骨关节炎兔膝关节，通过对关节滑液的ELISA分析证明外源基因的表达在基因转移后14天还很稳定，只接受hIL-1Ra基因治疗的膝关节软骨损坏明显减轻，接受hIL-10基因治疗的膝关节治疗也有一定效果，当两种基因同时导入时，有非常明显的抑制软骨破坏和软骨基质降解的作用。

The bioactivity of bFGF released from PLGA microspheres are higher than from PELA.(2) the bFGF released from PLGA microspheres can stimulate mitosis, proliferation, and matrix synthesis of chondrocyte more effectively than free bFGF. 10 days later after the administration of PLGA microspheres, the effects of stimulus to synthesis of type Ⅱ collagen and proteoglycan can be compared with continue administration of free bFGF.

游离bFGF对软骨细胞的促有丝分裂的作用效应期短；bFGF缓释微球能通过持续释放活性bFGF，在较长时期内促进软骨细胞的分裂增殖；Ⅱ型胶原免疫荧光测定和蛋白多糖阿新兰染色测定显示，应用微球10天后，能有效的促进软骨基质成分的合成，其效果与持续应用游离bFGF的效果相当。

The bioactivity of bFGF released from PLGA microspheres are higher than from PELA.(2) the bFGF released from PLGA microspheres can stimulate mitosis, proliferation, and matrix synthesis of chondrocyte more effectively than free bFGF.

游离bFGF对软骨细胞的促有丝分裂的作用效应期短；bFGF缓释微球能通过持续释放活性bFGF，在较长时期内促进软骨细胞的分裂增殖；Ⅱ型胶原免疫荧光测定和蛋白多糖阿新兰染色测定显示，应用微球10天后，能有效的促进软骨基质成分的合成，其效果与持续应用游离bFGF的效果相当。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。