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BACKGROUND: Many studies have achieved certain progress in repair of the osteochondral defect by tissue-engineered chondral composite graft which was constructed with different methods. But the existing problems of these methods are presented that the coupling of interfaces of bone and cartilage in graft and host is not ideal.

背景:国内外许多研究通过不同的构建方法构建组织工程化软骨支架复合体修复骨软骨联合缺损,且取得了一定的进展,但目前各种方法存在的问题突出表现为组织工程化的软骨和骨组织之间的界面、移植体和宿主骨和软骨之间的界面耦合不够理想。

The cartilage of germinative layer and basal layer grew better than that in bfgf group, magnetic group.

结果表明:磁场结合bfgf组在4周时基底层的软骨样组织增生,而磁场组、bfgf组少量软骨样组织增生。8、12周结合组透明样软骨层明显增厚,免疫组化ⅱ型胶原多。

In the MRI group, MR images were taken and assessed for location and severity of defects of cartilage by Noyes classification, osteophytes, subchondral cysts, sclerosis, meniscal and/or ligamentous tears.

MRI组根据MRI影像诊断软骨缺损的部位,对软骨缺损严重程度进行Noyes分级,对韧带、半月板、骨赘和软骨下骨囊腔改变情况进行评定,并诊断是否属于前内侧骨关节病变。

MSCT can nicely show the costal cartilaginous imaing, for on the live research costal cartilaginous anatomic shape to found a new pathed, is the best research method and have no wound in diagnosis costal cartilaginous disease.

结论多层螺旋CT能很好地显示肋软骨,为在活体上研究肋软骨形态学开创了一条全新途径,是一种无创伤性研究肋软骨疾病的最佳影像学方法。

Among them, 12 cases were microtia, and other 3 cases were aquired defects from injury. All cases underwent auricular reconstruction using retroauricular tissue expansion and autogenous costal cartilage framework.

行全耳再造术,移植自体肋软骨雕刻成耳软骨支架,利用扩张的耳后皮肤软组织制备皮瓣覆盖耳软骨支架,形成再造耳。

To study the etiology and treatment of relapsing polychondritis, especially tracheostenosis, 3 patients with severe relapsing polychondritis complicated with severe tracheostenosis were presented.

为提高对复发性多软骨炎尤其是合并气管严重狭窄的重症病例的认识,探讨复发性多软骨炎气管狭窄的病因和治疗方法,总结分析了 2 0例复发性多软骨炎中合并气管严重狭窄的重症复发性多软骨炎 3例。

Totally 32 healthy New Zealand rabbits received design of 6 cm ×2 cm random flaps on trachelo-back and simultaneous implantation of central arterial and venous bundles of left ear as well as free PC chaffs of right ear into flaps, which formed in different time island-like PC flaps taking vascular bundle as pedicle.

健康新西兰大白兔32只,在项背部设计6cm 2cm的任意皮瓣,将左耳中央动、静脉束及右耳游离的软骨膜片同时植入皮瓣下,在不同时间形成以该血管束为蒂的岛状软骨皮瓣,观察血管化进程;另在不同时间取出预构软骨皮瓣中的软骨膜,观察其形成软骨情况。

Drill of cross pin system was used to make defects vertically to cartilage face at condylus medialis femoris of left knee joint in rabbits.

用横穿钉钻头在兔左膝关节股骨内侧髁垂直于软骨面制造缺损,缺损深4 mm,直径4.45 mm,自体移植组取右膝关节内侧髁骨软骨柱植入到左侧膝关节相应缺损处,异体移植组将经过程序性深低温冷冻保存的同种异体骨软骨柱移植到相应缺损处。

Histological observation: Plenty of lymphocytic infiltrations around cartilage tissue could be observed in the untransfected group, and obviously decreased in the FasL-transfected group.

组织学观察:同种异体软骨细胞组软骨组织周围可见大量的淋巴细胞浸润,同种异体软骨细胞-FasL组明显减少。

OBJECTIVE: To detect the differential expression of ChM-Ⅰ and CTGF protein in MSCs, hyaline cartilage cells and elastic cartilage cells by Western blot assay.

目的:以Western blot检测软骨调节素Ⅰ和结缔组织生长因子在大鼠骨髓间充质干细胞、透明软骨细胞及弹性软骨细胞中的差异表达。

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