软骨形成

Results (1) High-density micromass cultures of Adipose -derivedmesenchymal stem cells could assemble themselves into small translucentspheroids that were visible to naked eyes as early as 48 hours after initialchondrogenic induction. Over the course of 12 days, the volume ofcartilaginous nodule increased. The induced ADSCs indicated round,triangular or multangular shape.

结果(1)在特定培养基诱导条件下，脂肪间充质干细胞细胞生长增殖明显减缓，细胞形态由梭型渐变为三角形、多角形、圆形，有自发聚集倾向，高密度的&微团&培养细胞在诱导后48小时可以聚集形成结节，并逐渐增大，12天左右结节呈半透明类软骨样外观。

The major characteristics of osteoarthritis are chronic and progressing osteoclasia of cartilage and new bone formation.

是以慢性进行性软骨破坏和新骨形成为主要特点的退行性疾病。

CD40/CD40L interactions were also shown to play a significant role in the maintenance of autoimmunity,High-level expression of CD40L and CD40have been detected on monocytes/macrophages from patients with active sgstemic lupus erythematosus,rheumatoid arthritis and other autoimmune diseases,indicating that the expression of CD40/CD40L on monocytes/macrophages could account for the formation of synovitis and osteoclasia.

CD40/CD40L是免疫细胞间的重要信号转导途径，单核巨噬细胞表达CD40与CD40L，分泌许多促炎性因子，参与类风湿关节炎滑膜炎形成、骨和软骨破坏。在系统性红斑狼疮、类风湿关节炎和其他自身免疫病中已检测出高水平表达的CD40与CD40L。

This study investigated the use of mechanical stimulation to promote cartilage rather than bone formation within an osteotomy.

本研究调查了截骨术后采用机械刺激促进软骨而不是骨形成。

The reason of the disease is uncertain and its pathologic change is chronic Inflammation of joints, cell infiltration, information of pannus and the erosion of cartilage and bones, which lead to the destruction and dysfunction of joints structure.

本病病因未明，主要病理变化为关节滑膜的慢性炎症细胞浸润、血管翳形成、软骨及骨组织的侵蚀，导致关节结构的破坏和功能丧失。

Results positive findings of MRI in shoulder joint as follow, synovitis and enhanced bilateral pannus (93.5%), bone erosion (77.9%), cartilage erosion (90.3%),change of synovium and bone marrow was taken as diagnostic standard, the sensitivity, specificity, accuracy, 69.0%、76.7%、72.3%.

分析病变早期E-MRI特征。结果肩RA MRI阳性表现，滑膜增生血管翳形成(93.5%)，骨侵蚀(77.9%)，软骨侵蚀(90.3%)等，以滑膜和骨髓改变诊断肩RA，其敏感性、特异性、正确率分别为： 69.0%、76.7%、72.3%。

Pectus excavatum is one of the commonly found congenital chest wall deformity. It is characterized by depression of the sternum and the lower costal cartilages, producing a concave appearance to the anterior chest wall.

漏斗胸是一项常见的先天性胸廓畸形，其病症为患者之胸骨，以及肋软骨向患者体内凹陷，而於患者前胸形成漏斗状之变形。

Under scanning electron microscopy, along with the extension of the culture time, the chondrocytes grew and propagated well on the surface. On 3 weeks, the cells adhered to the surface, and extended the pseudopodia, by which the cells were connected each other. The cells secreted matrix, which deposited around the cells and the surface of meniscus. In some area, the cells formed the structure like cartilage lacuna.

扫描电镜观察，随着培养时间延长，细胞在材料表面生长良好，细胞密度增加。3周时，可见细胞黏附在材料表面，有伪足伸出，细胞间通过伪足相互连接，并可见细胞分泌的大量基质沉积于细胞周围和材料表面，部分区域形成类似于软骨陷窝样结构。

Results: The cultured chondrocytes were polygonal cells. There were many rough endoplasmic reticula and mitochondria in cytoplasm, and a lot of secretory vesicles under cell membrane and in the cytoplasm. When cultured for 10 days, some small and white nodules were formed on the bottom of the culture dished, and volcanic-mouth-like structures were formed when cultured for 20 days. Both these nodules and structures contained GAG-positive substances were demonstrated by safranine-O staining.

结果：体外培养的软骨细胞为多角形，透射电镜下见胞浆内有丰富的粗面内质网系统及线粒体，胞膜下及胞浆中有较多分泌泡；连续培养10天时，培养瓶底部出现肉眼可见的白色结节，蕃红-O染色显示白色结节含大量氨基葡聚糖阳性物质，20天时形成火山口样结构，也被蕃红-O染成深红色。

Then 3 rabbits with 6 limbs of each group were killed in the 1st, 3, 5, 7, 10 and 13th week respectively, to compare the bone healing roentgenologically and histologically There was receptive reaction in fresh homogenous bone implant ati...

实验证明脱钙同种异体骨是一种较好的植入物。彼优于新鲜异体骨，与新鲜自体骨植入无显著差异。新骨及软骨出现在植入物中而不在邻近宿主骨处，表明新骨形成可能是骨诱导作用的结果。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。