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The condition results in delayed endochondral bone formation.

条件结果延迟软骨内骨形成。

These results indicate that rhBMP-2 induces the differentiation of mesenchymal cells to form new bone in the mode of endochondral ossification and endomembrane ossification.

实验结果证明,rhBMP-2以软骨内成骨和膜内成骨方式诱导间充质细胞分化形成骨组织。

DATA SYNTHESIS: Compared with the control group, VEGF can promote osteogenesis, bone formation and remodeling through the effect of VEGF on endochondral ossification and intramembranous ossification.

资料综合:与对照组相比,VEGF能通过对软骨内成骨、膜内成骨的影响促进骨的发生、形成和改建。

Bone morphogenetic proteins , a group of polypeptides within the transforming growth factor superfamily, were originally identified by their ability to induce endochondral bone formation in ectopic extraskeletal sites in vivo. BMPs family contains at least 20 members.

骨形态发生蛋白作为骨的生长因子属于转化生长因子-β超家族的一个成员,它的一个重要功能就是在非骨组织如肌肉中诱导新的软骨和骨形成。

Bones undergoing either intramembranous or endochondral ossification are continually remodeled from the time that initial calcification occurs until the final structure appears.

骨通过膜内骨化或软骨内骨化而不断的得以重塑,直至最后结构的形成。

Results: The degenerative changes were demonstrated in the knee joints injected with papain and L-cysteine, such as the lower activity scope of knee joint, thinner and worse articular cartilage, fissuration, fibrous degeneration, fibrillation and destroyed cartilage matrix.

结果:实验侧关节注射木瓜蛋白酶后,活动范围明显低于对照侧,关节软骨变薄且有裂隙形成、纤维变性、基质分解破坏等退行性改变,并随观察时间的延长而进一步发展。

For ADSCs at passage 3, the formation of red l ipid droplets within cells was observed 2 weeks after being induced towards adipocyte, red calcium nodules were evident 3 weeks after being induced towards osteoblast, and highly congregated cell mass positive for alcian blue staining appeared 2 weeks after being induced towards chondrocyte.

第3 代ADSCs 成脂诱导2 周,可见细胞内有红色脂滴形成;成骨诱导3 周,可见红色钙结节样改变;成软骨诱导2 周,可见高度聚集生长的细胞团,阿利辛蓝染色呈蓝色。

The major manifestations of MR imaging included synovial hyperplasia and pannus formation, joint effusion, bone marrow oedma, adnormality of signal and shape of meniscus, soft tissue swelling, cartilage destruction,popliteal lymphagogue, et al.

结果42例JIA患者的42个膝关节可见不同程度的MR异常改变(100%),主要影像学表现包括滑膜增生及血管翳形成、关节腔渗出积液、骨髓水肿、半月板形态及信号异常改变、关节软骨破坏、腘窝淋巴结肿大等。

Staining observation on complex mesochondrium of marrow-derived mesenchymal stem cells-TCP: It was found with TB staining that the complex of marrow-derived mesenchymal stem cells-TCP inside the joint cavity obviously had positive staining, which indicated that there were glycosidoprotein base formed.

骨髓基质干细胞-磷酸三钙复合体软骨基质特染观察结果:甲苯胺蓝染色发现,植入关节腔的骨髓基质干细胞-磷酸三钙复合体有明显阳性染色,表明有糖蛋白基质形成。

Then the bFGF was replaced by transforming growth factor-β1 (TGF-β1 10 μg·L-1) for next three weeks. Results Some spindle MSCs turned into round or elliptic shape and secreted metachromatic matrix with Toluidine blue.

结果:细胞形态由纺锤形变为圆形或椭圆形,细胞分泌了大量的甲苯胺蓝异染的基质,形成了类软骨陷窝。

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