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With further study on the effects of BMPs on chondrogenesis and other process that benefits the chondrocyte repair, BMPs will open a new and prospective era of chondrocyte repair.

骨形态发生蛋白在促进软骨修复方面的作用有良好应用前景,随着研究的不断深入,关节软骨修复这个临床上的难题将有望被突破。

RESULTS: In the SH-rhBMP-2 group, sparse chondroid tissue could be found at the 2 weeks of operation, which arranged orderly along the tibial tunnel from 4 to 8 weeks, tendon adhered to adjacent tissue stably, and bony tissue was appeared at the 12 weeks.

结果:透明质酸钠-重组人骨形态发生蛋白2亚组在术后2周隧道内见稀疏软骨样组织,4~8周时隧道内见沿骨隧道排列的软骨样组织,双股肌腱之间形成稳定组织连接。l2周时出现部分骨样组织包裹肌腱。

Results After lengthing, obviously histological variety was observed on the sections of condyloid process and intercondylar disc,but it could be repaired under 1mm/d distraction rate.

结果:牵张后大体观察可见关节盘无显著形态异常,髁状突有不同程度适应性改建;组织学主要表现为关节盘不同程度中带变薄,纤维走行改变,血管侵入,后带变厚;髁状突表现为纤维软骨组织形态学的改变和软骨、骨的改建活动,2mm/日组可见破坏现象发生。

Radiographs allowed preoperative assessment of the degree to which varus or valgus angular deformity was correctible. the accuracies of the cartilage defects, which were noyes ⅱb,ⅲa,ⅲb, measured by mr imaging were 66.7%, 75% and 65.5%. but mri can not predict if the preoperative varus/valgus deformities were correctible.

结果]摄片组误差主要发生在对oa较少累及间室及较浅表的软骨缺损情况进行判定时,能够鉴别膝内/外翻崎形能否被动矫正。mri判断noyes ⅱb,ⅲa,ⅲb软骨缺损的准确率分别为66.7%, 75%和 65.5%,但不能判定膝内/外翻崎形能否被动矫正。

There are more than two dozen reported cases of lumbar facet dislocation after rapid deceleration injuries (e.g., traffic accidents), most involving L5 S1.61,112 115 The mechanism of injury in these cases is purported to be a combination of hyperflexion, distraction, and rotation.61,112,116 In a posthumous study conducted in 31 lumbar spines of subjects who died of traumatic injuries,Twomey et al.117 found occult bony fractures in the superior articular process or subchondral bone plate in 35% of victims, and z-joint capsular and/or articular cartilage damage in 77% of cases.

多项研究报道了急性减速伤后发生腰椎小关节分离,多数发生于L5-S1,其机制可能为过度屈曲,分离和旋转。在一项对死亡病例的研究中,Twomey 等发现,31例因交通事故死亡的人中有35%的腰椎上关节突或软骨下骨性终板存在隐匿骨折,77%存在小关节囊和/或关节软骨损伤。作者总结创伤后隐匿性股和软组织损伤也许是腰痛的来源。

There are more than two dozen reported cases of lumbar facet dislocation after rapid deceleration injuries (e.g., traffic accidents), most involving L5 S1.61,112 115 The mechanism of injury in these cases is purported to be a combination of hyperflexion, distraction, and rotation.61,112,116 In a posthumous study conducted in 31 lumbar spines of subjects who died of traumatic injuries,Twomey et al.117 found occult bony fractures in the superior articular process or subchondral bone plate in 35% of victims, and z-joint capsular and/or articular cartilage damage in 77% of cases.

多项研究报道了急性减速伤后发生腰椎小关节分离,多数发生于L5-S1,其机制可能为过度屈曲,分离和旋转。在一项对死亡病例的研究中,Twomey 等发现,31例因交通事故死亡的人中有35%的腰椎上关节突或软骨下骨性终板存在隐匿骨折,77%存在小关节囊和/或关节软骨损伤。

Osteochondromas, or osteocartilaginous exostoses, are the most common primary benign bone tumors and usually occur in the metaphyses of long bones.

骨软骨瘤,或称骨软骨外生骨疣,是最常见的原发性良性骨肿瘤,通常发生于长骨的干骺端。

In histopathologic examine, pannus was infiltrating the articular cartilage during 10 to 31 days after injection and monocuclear leukocyte infiltration was found.

实验性化脓性关节炎早期关节软骨的MRI改变是单纯的信号改变,化脓性关节炎后期软骨形态开始发生变化。

Concentrations of Pyr in cartilage and subchondral bone changed with the progress of OA, which perhaps connected with the high excretion of Pyr in urine.

OA关节软骨及软骨下骨的Pyr含量随病程发生变化,可能是造成经尿液排Pyr升高的原因。

Objective To investigate the role of SOX-9(SRY-related high mobility group box gene 9)regulating the apoptosis in the hyaline cartilage cells of human cervical zygapophysial joints.

目的 探讨重组腺病毒介导的人SOX-9(AdSOX-9)对人的颈椎关节突关节软骨细胞凋亡细胞数目及Caspase-3基因表达的作用及相关意义,更好理解颈椎软骨退变的发生机制。

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然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

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