软骨发生

Objective: To investigate the expression of the progressive ankylosis gene in both the normal and degenerative cervical vertebral endplate chondrocyte for the pathogenesis of intervertebral disc degeneration.

目的：观察ANKH蛋白在正常颈椎软骨终板和退变软骨终板中的表达差异，探讨椎间盘退变的发生机理。

Such children were not caused by the throat-ming weakness caused by laryngeal cartilage, but when inspiratory arytenoid cartilage move downward rotation, the relaxation of their organizations to the sound in front of the Ministry of processes, blocking occurs supraglottic laryngeal ming.

这种患儿之喉鸣并非因喉软骨软弱所致，而是当吸气时杓状软骨向前向下转动，其上的松弛组织向声门前部突起，阻塞声门而发生喉鸣。

Cartilage-derived morphogenetic protein 1(CDMP1) is one kind of important bioactivity factors participated in cartilage cell differentiation.

前期实验已证实了软骨形态发生蛋白1诱导大鼠脂肪干细胞体外可向软骨细胞形态分化，但是能否在体内成软骨呢？

RESULTS: Scanning electron microscopy showed that cartilage cell and ADSCs induced by CDMP1 grew well in cattle spongy bone scaffold, with mean pore diameter of 382 μm.

结果：扫描电镜示，软骨细胞和经软骨形态发生蛋白1诱导的脂肪干细胞在自制牛松质骨支架上均生长良好，平均孔径约为382 μm。

HGF can regulate the proliferation and differentiation of chondrocyte both in vivo and in vitro.

外源性HGF能加强骨、软骨的形态发生，提高培养软骨细胞Ⅱ型胶原mRNA的表达和碱性磷酸酶活性。

Until recently, it generally was thought that there was no effective clinical treatment that could restore a damaged cartilage and prevent the normal sequelae of degenerative joint disease, for the repair tissue typically was classified as fibrocartilage and was not hyaline.

由于以往的修复技术产生的修复组织通常为纤维软骨而非透明软骨，最终都发生退变，因此，目前还普遍认为临床缺乏有效的治疗手段来治疗软骨损伤。

Bone morphogenetic proteins can enhance the cartilage repair, and may be important in the future for cartilage defect.

骨形态发生蛋白可促进软骨生成和修复，在关节软骨修复上有着很好的前景。

METHODS: In the experimental group, ADSCs were cultured with the scaffold and induced by CDMP1(50 μg/L) in basic medium for another 2 weeks. In the control group, SD rat cartilage cells were cultured with elementary nutrient liquid with scaffold for another 2 weeks. Twenty nude mice were imbedded the composite of cells-scaffold of the experimental group in their left armpits and the composites of cells-scaffold of the control group in right armpits. Every ten nude mice were killed at 8 and 12 weeks and were examined by safranine O-fast green and toluidine blue staining.

体外培养的脂肪干细胞复合于支架上，加入诱导液(基础培养液+ 50 μg/L软骨形态发生蛋白1)继续培养2周作为实验组；将SD仔鼠软骨细胞复合于支架上，常规培养2周作为对照组。20只裸小鼠，左侧腋窝皮下均植入实验组细胞-支架复合物，右侧腋窝皮下均植入对照组细胞-支架复合物。8， 12周各处死10只，行甲苯胺蓝和番红O-固绿染色。

Then, under the control of systemic factors, mesenchymal cells aggregate and differentiate to form catilage blastemal elements that prefigure skeletal limb components.

脊椎动物胚胎期骨与关节系统的发生是一种复杂生命现象，起始于中胚层间充质细胞的定向聚集，形成肢芽，然后在一系列作用因子的调控下，肢芽内细胞进一步分化，形成具有骨骼雏形的软骨原基，后者经软骨内骨化发育成骨。

BMPs have the effect of promoting chondrogenous repair, chondrogenous differentiation, matrix forming, and inhibiting the dedifferentiation process.

骨形态发生蛋白对关节软骨修复具有促进作用，有促进软骨分化、基质形成，并抑制软骨细胞去分化等作用。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。