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Twenty-four hours after the last oral administration, the blood were obtained and used for testing adrenocorticotrophic hormone, cyclic adenosine monophosphate, cyclic guanosine monophosphate, glucose, cholesterol, alanine aminotransferase, urea nitrogen. Results Before taking medicine, model rats' cAMP/cGMP and ACTH were lower than normal rats', and they showed a trend of rise with adding dose. Before taking medicine, model rats' GLU was lower than normal rats'. With adding dose, model rats' GLU increased, however, normal rats' GLU reduced. When taken medium dose white prepared lateral root of aconite, model rats' CHO was higher than normal rats'. Taking medicine made both groups ALT rise, but normal rats' went up more quickly than model rats'. Model rats' BUN was higher than normal rats', and taking low dose or little dose medicine could lead to incline of reduction.

结果 给药前模型组环磷酸腺苷/环磷酸鸟苷和促肾上腺皮质激素低于正常组,随着给药剂量的增加,两者有升高的趋势;给药前模型组血糖低于正常组,随着给药剂量的增加,模型组GLU有升高的趋势,而正常组有下降的趋势;中剂量给药时模型组总胆固醇显著高于正常组;随着给药剂量的增加,2组丙氨酸氨基转移酶均有升高的趋势,且正常组ALT升高的幅度更大;给药前模型组尿素氮高于正常组,低、小剂量给药有降低模型组BUN的趋势。

Results: T-588 administration successfully preented motoneuron loss and ameliorated the choline acetyltransferase immunoreactiity in the ipsilateral nucleus ambiguus after agal nere aulsion.

结果:T-588给药成功的阻止了运动神经元的丢失,并且改善了迷走神经撕脱伤后同侧疑核胆碱乙酰基转移酶免疫反应性。

The neuroprotectie effects of T-588 administration after agal nere aulsion and neurofunctional recoery after recurrent laryngeal nere crush were studied using motoneuron cell counting, ealuation of choline acetyltransferase immunoreactiity, the electrophysiologic examination, and the re-mobilization of the ocal fold.

本文采用运动神经元细胞记数、胆碱乙酰基转移酶免疫反应性、电生理学检查和声带再运动情况的方法来研究在迷走神经撕脱伤后T-588给药的神经保护作用和喉返神经挤压损伤后神经功能的恢复。

Background: Alanine aminotransferase predicts the development of Type 2 diabetes mellitus and cardiovascular disease in Caucasian subjects.

背景:在具有2型糖尿病和心血管病的白种人患者中,丙氨酸氨基转移酶预计会增高。

Anoxemia Hypercapnia Morris water maze Choline acetyl-transferase Puerarin

低氧血症;高碳酸血; Morris水迷宫;胆碱乙酰转移酶;葛根素

SDS-PAGE analysis revealed that the GST-HF93 fusion protein had an apparent molecular weight of 38 kD and accumulated up to 50% of bacterial soluble proteins.

表达产物经谷胱甘肽S转移酶亲和层析柱纯化,得到的融合蛋白纯度达90%以上。

In multivariate analyses, IPC had an independent effect only on day 2 aspartate transferase.

多元分析提示IPC仅对于移植后2天的天冬氨酸转移酶存在独立的作用。

Using comparative molecular field analysis and comparative molecular similarity indices analysis, three dimensional structure-activity relationship (3D-QSAR) studies were carried out on a series of benzofuran N-myristoyl transferase inhibitors.

采用比较分子力场分析法和比较分子相似性指数分析法,系统地研究了40个苯并呋喃类N-肉蔻酰基转移酶抑制剂的三维定量构效关系。

AbstractUsing comparative molecular field analysis and comparative molecular similarity indices analysis, three dimensional structureactivity relationship(3D-QSAR) studies were carried out on a series of benzofuran N-myristoyl transferase inhibitors.

摘要采用比较分子力场分析法和比较分子相似性指数分析法,系统地研究了40个苯并呋喃类N-肉豆蔻酰基转移酶抑制剂的三维定量构效关系。

The cloning of bar gene is important to plant transgenic engineering, gene expression and studying physiology.In the experiment, the full code sequence of bar gene was cloned by PCR from transgenic herbicide resistant Bobwhite wheat and checked. It was expressed in E.coli and its protein was determined.

本实验从抗除草剂转基因Bobwhite小麦中,利用PCR克隆的方法扩增出bar基因全长,并在原核表达系统中表达,鉴定表达蛋白的活性,将能够正确编码PPT乙酰转移酶的bar基因片段,经过适当的修饰构建入真核表达载体。

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