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Furthermore, androgen receptor and the ERG gene fusion product coordinately regulate components of the sarcosine pathway.

基因敲除甘氨酸N-甲基转移酶(此酶促进甘氨酸转化为肌氨酸)后,前列腺癌的侵袭性减弱。

To understand the toxicity mechanisms of mixed heavy metals on aquatic plant,indicators of algea growth rate,content of reduced glutathione,activities of glutathione S-transferase and glutathione peroxidase of green algae, Scenedesmus quadricauda were measured to analyze the individual and joint toxic effects of lead and mercury.

为进一步了解重金属复合污染对水生植物产生毒害作用的机制,以单细胞藻类生长及细胞内还原型谷胱甘肽含量、谷胱甘肽-S-转移酶和谷胱甘肽过氧化物酶活性为指标,对铅和汞单一及联合胁迫对四尾栅藻的毒性作用进行了研究。

Objective: To investigate the expression and their correlation of P-gp,GST-π,TopoⅡ and p53 in breast carcinoma.

目的:探讨乳腺癌中P-糖蛋白,谷胱甘肽-S-转移酶,拓扑异构酶和P53的表达及相关性。

METHODS We performed immunohistochemical staining on 192 circumferential venoatrial segments (32 veins) harvested from 8 autopsied human hearts using antibodies to tyrosine hydroxylase and choline acetyltransferase.

研究者利用酪氨酸羟化酶及乙酰胆碱转移酶抗体对从8名尸解的人体心脏中采集的192例肺静脉同左心房连接处周缘的肌肉片断(32个静脉)进行免疫组织化学染色。

The qualitative and quantitative analysis of schizophrenia and single nucleotide polymorphism of catechol-O-methyltransferase , Proline Dehydrogenase and DYSBINDIN genes were done by using transmission disequilibrium test . Results:(1) The symptoms of first-episode schizophrenia were divided into four independent symptom dimensions: psychomotor poverty, reality distortion, disorganisation and depression-anxiety.

4采用传递不平衡检验、单倍型传递不平衡检验和定量性状传递不平衡检验的方法对6号、22号染色体上3个候选基因,即儿茶酚氧位甲基转移酶(catechol-O-methyltransferase,COMT)、脯氨酸脱氢酶(Proline Dehydrogenase,PRODH)和DYSBINDIN基因的9个单核苷酸多态性(single nucleotide polymorphism,SNP)位点与精神分裂症、神经认知功能、人格特质和临床症状表现的关系进行了定性和定量的遗传学分析。

The over expression of p33^ING1b can promote the expression of p21^WAP1 which cooperates with p53 to restrain the cell growth by regulating the activity of the acetylating depended pathway.

ING1编码的蛋白通过组蛋白乙酰转移酶和组蛋白去乙酰化酶参与染色质的重塑,在DNA损伤修复方面发挥重要作用。

Effects of processing parameters such as transglutaminase concentration, pH value of film-forming solution and air-drying temperature on the properties of TGase-modified soy protein isolate films were studied in this manuscript.

研究了酶浓度、成膜溶液的pH值、干燥温度等工艺参数对谷氨酰胺转移酶改性大豆分离蛋白膜性能的影响。

The specific inhibitor of DNA methylation that is available currently is 5-Aza-2'-deoxycytidine (5Aza-dc), which forms a covalent bond with the DNA methyltransferase, thus, limiting the number of free DMT molecules for methylating DNA and then decreasing its biology activity.

目前研究较多的甲基化抑制剂是胞苷类似物5-氮杂-2'-脱氧胞苷(5-Aza-2'-deoxycytidine, 5Aza-dc)。5Aza-dc的作用机制是与DNA甲基转移酶共价结合,降低酶的生物活性。

Selecting the better amplified from Diacylglycerol acyltransferase, gene, Acyl- desaturase gene ,then cloning sequencing, afer that, through the NCBI and nucleotide sequence to match homology , the results show that: cloning by the cassava, castor-oil plant Jatropha curcas DGAT and SAD genes and gene fragments have the high homology with other known plant DGAT genes and SAD genes .

从中筛选出扩增效果较好的二酰基甘油酰基转移酶(Diacylglycerol acyltransferase, DGAT)基因,硬脂酰-酰基载体蛋白脱饱和酶(Acyl- desaturase, SAD)基因克隆测序,经测序,通过NCBI与已知的核苷酸序列进行同源性比对,结果表明:克隆所获得的木薯、蓖麻和麻疯树 DGAT基因和SAD基因的片段与其它已知植物的DGAT基因和SAD基因具有很高的同源性。

W. . The levels of myocardial troponin I, creatin kinase, aspartate transamnaseand lactatede hydrogenasewere detected before and per 30 mins during the experiment, and the changes of rabbit myocardial pathology were analyzed.

分别于实验前和实验中每隔30分钟抽取血液,以肝素抗凝并分析心肌肌钙蛋白I浓度,肌酸激酶、门冬氨酸氨基转移酶和乳酸脱氢酶活性,同时观察心肌组织的病理学变化。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。