转移瘤

Methods Twenty-three cases of neuroblastoma with bone marrow metastasis were reviewed and studied by light microscopy and immunohistochemical staining.

对23例神经母细胞瘤骨髓转移的临床病理资料进行分析，并做光镜观察及免疫组化染色。

Objective To evaluate the safety and pain palliation effects of zoledronic acid in patients with solid tumor who previously received bisphosphonate therapy.

目的 评价唑来膦酸治疗既往用过双膦酸盐的实体瘤骨转移患者骨疼痛的缓解效果和安全性。

There were no false positive reports among the 220 (40.1%) biopsies interpreted as benign lesions in paraffin sections. Among 329 (59.9%) malignant biopsies on paraffin sections, 3 cases were interpreted as benign lesions on frozen sections. Three false negatives included 2 ductal carcinoma in situ and one infiltrating ductal carcinoma associated with papillomatosis. The tumors were small and confined to the breast without any evidence of metastasis.

本研究针对五年来本院 549 例乳房病理冰冻切片及永久性石蜡病理切片诊断比较，发现在 220 例的良性乳房病变40.1%）并未发现任何假阳性的冰冻病理切片诊断，而在 329 例（ 59.9 %）恶性乳房病变中，其中有三例假阴性包含二例乳房管道原位癌及一例合并良性乳突瘤的浸润性乳癌，而这三例均属较小病变及未有腋下淋巴腺转移。

Results: VIP receptors and secretin receptors were demonstrated in tumor-free colon and colon tumors.

结果：无肿瘤结肠、结肠腺瘤、结肠癌、结肠癌肝转移灶组织均表达了VIP和胰泌素受体。

The chemotherapy alone is not significant to life span in tumor bearing mice with metastasis, breviscapine can improve therapeutic index of chemotherapeutic agents for tumor.

单独化疗对伴随肿瘤转移的荷瘤小鼠生命延长无实际意义，灯盏花素能改善肿瘤化疗药物的治疗指数。

Carbon dioxide has auxoaction on the growth of the human ovarian carcinoma cell line SKOV3 xeno-transplanted into nude mice, but has no effects on tumor metastasis.

CO2气体本身对人卵巢癌SKOV3细胞裸鼠皮下移植瘤的生长有明显的促进作用，对转移影响不大。

Carbon dioxide has auxoaction on the growth of the human ovarian carcinoma cell line SKOV3 xenotransplanted into nude mice, but has no effects on tumor metastasis.

结论CO2气体本身对人卵巢癌SKOV3细胞裸鼠皮下移植瘤的生长有明显的促进作用，对转移影响不大

Objective 1. To investigate the expression of protein of nometastatic gene 23(nm23H1),vescular endothelial growth factor and protein of nuclear factor kappa B ( NF-kBP65) in retinoblastoma, blepharal basal cell carcinoma , blepharal squamous cell carcinoma and meibomian gland carcinoma. 2. To explore the relationship between expressions of these proteins and biological behavior of these ocular malignancies.

目的：1、检测肿瘤转移抑制基因蛋白nm23H1、血管生成因子VEGF以及细胞核因子NF-kBP65蛋白在视网膜母细胞瘤、眼睑基底细胞癌、眼睑鳞状细胞癌和睑板癌中的表达。2、探讨它们与眼部恶性肿瘤的生物学行为的关系。

Based on these previous work, in this research, in order to explore the the molecular mechanism of enhanced tumor cell immunogenicity treated by elemene and mytomycin C compositely, we used murine Hca-F ascitic hepatic carcinoma ( high lymphatic metastasis substrain of H22) as an experimental model to compare the immunoprotective effects on Hca-F cells as well as the mechanism of the effects caused by HSP70-peptide complex purified from untreated tumor cells, EC-TCV and BCG; We studied the mechanism of increased tumor cell membrane HSP expression treated with elemene by the techniques of RT-PCR and immunoelectron microscopy; In order to deeply elucidate the antitumor effects and the molecular mechanism of elemene in increasing tumor cell immunogenicity we analyzed and compared the effects of elemene and heat shock on the gene expressions of tumor cell using gene expression profile chip.

本论文在上述研究成果的基础上，选择小鼠肝癌H22的高淋巴道转移亚系Hca-F为模型，进一步比较了未处理肿瘤细胞来源、榄香烯复合瘤苗来源的和卡介苗来源的HSP70-肽复合物对Hca-F的免疫保护效应、效应机制，探讨榄香烯-丝裂霉素复合处理增强肿瘤细胞免疫原性的分子机制；以Hca-F和人肝癌细胞株HepG〓等为模型研究了榄香烯处理增强肿瘤细胞膜热休克蛋白表达的机制；以HepG〓为模型用表达谱基因芯片研究比较了榄香烯与热休克处理对肿瘤细胞基因表达的影响，从而进一步阐明榄香烯抗肿瘤作用及增强肿瘤细胞免疫原性的分子机制。

Results Among the 12 cases cystosarcoma phyllodesand, 5 cases underwent total mastectomy, 2 cases underwent modified radical masteetomy, 1 case underwent local excision and reserve nipple, and 4 cases underwent lesion removed and reserve nipple or gland.

结果 12例乳腺叶状囊肉瘤中，行单纯乳房切除术5例，改良根治术2例，保留乳头皮下乳房切除术1例，保留乳头和部分压缩腺体加肿块切除术4例；术后随访1～18年，失访1例，2例分别于术后1.5年、2年出现肿块复发，再次手术切除，其余患者无复发或转移，并元瘤生存。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。