转移瘤

Transduction of TNF-α gene into TIL of human glioma by retroviral vectors and study of its biological activity in vitro. The development of retroviral vectors for TNF-α gene transfer and preparation of carrier cells-TIL have al- lowed transducing marked gene NeoR and purpose gene TNF-α into TIL cells respectively by use of monoclone tilter virus PLC-2 and PLJC-5. Detect the proliferation of TIL, expression of TNF-α and the anti-tumor activity of glio- ma TJ8510 cells in vitro.

在TNF-α逆转录病毒转移系统的建立及运载细胞TIL制备的基础上，利用构建的单克隆高滴度病毒细胞株PLC-2和PLJC-5将标记基因NcoR和目的基因TNF-α分别导入到TIL细胞中；对TNF-α基因转导后的TIL细胞进行细胞的增殖情况、TNF-α表达水平及对人脑胶质瘤TJ8510细胞的体外抗瘤活性的检测。

Of the 5 patients with available follow-up, 3 were free of disease at 1, 5, and 8 years after orchiectomy (2 necrotic seminomas and 1 germ cell tumor, unclassified). One patient with yolk sac tumor (age 63 y) developed widespread metastases after 15 months and died of disease.

随访了5例患者，其中3例于睾丸肿瘤切除术后1、5和8年任健在且无复发（2例为坏死的精原细胞瘤、1例为未分类的生殖细胞肿瘤）。1例为内胚窦瘤（63岁），15个月后广泛转移，并死于本病。

The main imaging features of CT were included the solid portion of tumors enhancement, necrosis and cystiform degeneration within the mass, more than half of the mass lay outside the cavity in many cases, the CT imagings of metastasis were similar as primary tumors.

CT扫描表现为肿块实质部分静脉期强化较动脉期明显，瘤体内可见液化坏死、囊变，多数瘤体以腔外生长为主，邻近胃肠道壁无增厚，转移病灶与原发灶的CT表现相似。

Results 12 cases as abdominal hernia (of which indirect hernia 9 cases, direct hernia 2 cases, femorocele 1 case), ultrasonography shows middle-high echo or linkage heterogeniety echo clumps; 8 cases as hydrocele, Ultrasonogram shows anechoic; 2 cases as cryptorchidism, ultrasonography shows normal testicular middle-echo; 4 cases as lymph node mass (of which lymphoma 2 cases, lymph node metastasis 1 case, lymph node inflammatory change 1 case), acoustic image shows low weak echo; 4 cases as substance mass (of which fibroma 1 case, spermatic cord tumor 1 case, Desmoid tumor 1 case, spermatic cord inflammation 1 case), Ultrasonography shows non-uniformity middle-highor low echo.

结果 12例为腹外疝（其中斜疝9例、直疝2例、股疝1例），声像图表现为中高回声或混杂性回声团块；8例为鞘膜积液，声像图表现为无回声；2例为隐睾，声像图表现为似正常睾丸样中等回声；4例为淋巴结包块（其中淋巴瘤2例、淋巴结转移1例、淋巴结炎性改变1例），声像图表现为低弱回声；4例为实质性包块（其中纤维瘤1例、精索肿瘤1例、韧带样瘤1例、精索炎症1例），声像图表现为非均匀性中高回声或低回声。

Microscopically, the tumor in the sigmoid colon showed sheet-like growth of epithelioid cells with abundant clear cytoplasm and round nuclei, which were separated by thin fibrovascular septa.

影像学显示乙状结肠壁肿瘤，其表现不同于神经母细胞瘤。此外，腹股沟和颈部淋巴结有神经母细胞瘤的转移。

Neoplastic cells are hepatoid with large vesicular nuclei, prominent nucleoli, and plump polygonal eosinophilic cytoplasm.

而相对少见的良性肿瘤包括肝脏腺瘤、血管瘤和平滑肌脂肪瘤，当然转移性的肿瘤也比较多见。

TTF-1 was found to be positive in 8 of 48 (16.6%) nephroblastomas and negative in all 5 metanephric adenomas. WT1 was positive in 43 of 48 (89.6%) nephroblastomas and 4 of 5 (80.0%) metanephric adenomas.

在他的肺部转移灶中，我们意外观察到瘤细胞核的甲状腺转录因子1（TTF-1）的免疫反应与Wilms氏瘤1型蛋白（WT1）免疫反应的明显缺失相关。

eIF4E and MMP-9 expression was significantly higher in supraglottic and hypopharyngeal carcinoma than distant margin and normal mucosa tissue.

eIF4E、MMP-9在喉痛及下咽癌瘤体中的表达高于癌周正常组织，eIF4E在瘤体及癌周正常组织表达阳性率高于MMP-9.eIF4E可作为预测喉癌及下咽瘢浸润生长、转移的敏感标志物。

Results:(1) All of HCC were irregular hyperdense in arterial phase companioned with mass and hyperdense tumor vessels.

结果 ：( 1)肝动脉期肿瘤实质出现密度高于肝实质的肿瘤血管和瘤区强化，门静脉期其密度迅速降低，至平衡期为低密度；( 2 )肿瘤边缘于肝动脉期和门静脉期均可见环行强化；( 3)转移性子灶仅在肝动脉期明显强化，门脉期全瘤密度迅速降至等密度；( 4)门静脉受累表现为肝内分支的边缘侵蚀、破坏、中断，或为不规则的充盈缺损。

The invasion and metastasis occurring in footpads and lymph nodes were observed and computed, the expression of VEGF, MVD were also me asured with immunohistochmeistry staining.

结果 麝黄消瘤方治疗组与模型组相比，其局部瘤组织的侵袭和腘窝淋巴结转移程度及淋巴结指数有降低趋势，其中大剂量组有显著性差异(P＜0.05)；大中剂量组可使胸腺指数明显升高(P＜0.05)。

Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在，'歼灭战perfuming自己与胡努特，那麼，他来到和SAT 。