转位的

The peroxisome proliferator-activated receptors play an important role in adipocyte differentiation and fatty acid metabolism, activation of PPAR may induce the differentiation of adipocyte,influence the expression of genes involved in lipogenesis and fatty acid oxidation,eventually lessen ectopic fat accumulation and improve the impaired insulin signaling,so the medicine which targets to the control point of FFA metabolism would be hopeful in the treatment of a cluster of metabolic abnormalities resulted from insulin resistance.

过氧化物酶体增殖物激活受体在脂肪细胞分化、脂肪酸代谢中起重要作用，PPAR及其所调控基因的激活可促进脂肪细胞分化、减少脂质产生、增加脂肪酸氧化，从而减少脂质的异位沉积，进一步改善损伤的胰岛素信号转导通路，逆转胰岛素抵抗。针对脂肪酸合成及氧化的关键调控点的药物可能是今后治疗胰岛素抵抗引发的一系列代谢异常的新的靶点。关键词过氧化物酶体增殖物激活受体；脂肪酸代谢；胰岛素抵抗

Antigene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis Roberto Tonelli,Stefania Purgato,Consuelo Camerin,Raffaele Fronza,Fabrizio Bologna,Simone Alboresi,Monica Franzoni,Roberto Corradini,Stefano Sforza,Andrea Faccini,Jason M. Shohet,Rosangela Marchelli,and Andrea Pession Department of Pediatrics, University of Bologna,Sant'Orsola-Malpighi Hospital, Bologna, Italy; Department of Organic and Industrial Chemistry, University of Parma, Parma,Italy; and 3Center for Cell and Gene Therapy, Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas Abstract We developed an antigene peptide nucleic acid for selective inhibition of MYCN transcription in neuroblastoma cells, targeted against a unique sequence in the antisense DNA strand of exon 2 of MYCN and linked at its NH2 terminus to a nuclear localization signal peptide.

抗原肽核酸抑制MYCN具体表达的神经母细胞瘤细胞，导致细胞生长的抑制和凋亡罗伯托利，斯特凡Purgato ，苏埃洛卡默琳，拉菲尔Fronza ，梅奥尼博洛尼亚，西蒙娜Alboresi ，莫妮卡弗兰索尼，罗伯托Corradini ，斯特凡诺斯福尔扎，安德烈Faccini ，杰森先生Shohet ， Rosangela Marchelli ，和安德烈Pession儿科，博洛尼亚大学，圣' Orsola -马尔皮基医院，博洛尼亚，意大利；有机部和工业大学化学帕尔马，帕尔马，意大利和3Center的细胞和基因治疗，德州儿童癌症中心， Baylor医学院，得克萨斯州休斯敦摘要我们开发了一种抗原肽核酸的选择性抑制神经母细胞瘤MYCN转录细胞，针对一个独特的序列反义DNA链的第2外显子，并与在MYCN 其氨基端为核定位信号肽。

Khosla's investments include Calera, a carbon-capturing-cement start-up founded by a Stanford expert in medical cement; Amyris, which has Berkeley malaria researchers working to turn sugar into diesel; and Soladigm, which exploits semiconductor-industry expertise to make energy-efficient windows.

科斯拉的投资包括由一位斯坦福大学医用水泥专家新成立的吸碳水泥制造公司Calera，有多名加州大学伯克利分校疟疾研究人员研究糖转柴油技术的Amyris以及利用半导体技术生产高效节能窗户的Soladigm。

About a month ago, I visited the spacious ShanxiHistoryMuseum, lingering from room to room as if traveling through ages from remote times to recent days, from primeval chaos to civilization, from war to peace, from poverty to prosperity…When I saw a rusty ancient wine vessel, I will think which triumphant general drank the celebrative wine in it.

一个多月前，我徜徉于博大的陕西历史博物馆，一间厅一间厅地转过去，从远古走到近代，从洪荒走到文明，从战争走到和平，从贫乏走到繁荣……看到那生锈的樽，我会想，不知道哪一位凯旋的将军喝了它盛的庆功好酒？

The precise sequence and the substructural context of an NLS or NES defines its specificity for the various Kaps (21 )Furthermore, the receptorproteinand receptor-RNA interactions that mediate

一个核定位信号序列和核输出信号序列的精确序列和结构成分，决定了它对各种各样Kaps蛋白的专一性，而且，调节物质定位的蛋白受体和RNA受体相互作用由各种转录和翻译后加工所控制，这考虑到了介质本身精确运输的调节。

The case reported here was of a 63-year-old man from Denmark who had been referred to their institution and received implanted electrodes overlying the temporoparietal junction on the right side in an attempt to suppress intractable tinnitus.

这里所报导的是一位63岁来自丹麦的男性，他已经被转介到当地的机构，且接受植入电极，位置在右侧的颞顶叶交界处，目的是在压抑难以治疗的耳鸣。

While Muslim greybeards deliberated, two leading figures in the eastern Christian world—the Ecumenical Patriarch, Bartholomew I, and the newly enthroned Patriarch Kyrill of Moscow—held a joint service nearby that signalled a warming in their relations and a common commitment to cool and generally improve the world.

就在穆斯林的灰白胡子们深思熟虑的时候，东方天主教世界的两位主要人物——普世牧首巴尔多禄茂一世和新任莫斯科大牧首基里尔一世——在附近联手主持了宗教仪式，这标志着他们关系的转暖以及对全球降温和总体改进做出共同承诺。

The properties of the shear layers are analyzed in the states of purely laminar, fully turbulent and laminar+transition+turbulent using the Thwaites Integral and Head Integral methods.

文中采用的数值求解过程为：首先求解给定翼型的位流速度分布，在此基础上采用Thwaites积分法和Head积分法，分别计算纯层流、纯湍流以及层流+转捩+湍流这三种流态的边界层，分析三种流态的边界层特性。

And such power did he attain, with only himself to thank for it, that, in a division of the whole empire into two portions, he took and received the nobler one; and, absent himself, by his mere subalterns and lieutenants often defeated the Parthians, and drove the barbarous nations of the Caucasus back to the Caspian Sea.

不过虽然老爹没给安东尼留下什么好处，凯撒遇刺倒是把这位传奇统帅奋斗一生的成果全部拱手转到了安东尼的户头上。安东尼权柄在握之时，大概只有他自己才会感激上苍让伟大的罗马一分为二，而自己捞到那块肥一点的。

The violinist and teacher Boris Schwarz believed that it was "only a quirk of fate" that Heifetz's renown so outstripped Milstein's. Another scholar of the violin, Henry Roth, disagreed, citing Heifetz's opulent tone and dashing, larger-than-life artistic personality as the key to his popular success -- qualities Milstein neither sought nor seemed to need.

小提琴家兼教师包里斯*舒瓦兹相信海非兹的名气会凌驾与米尔斯坦之上仅是因为&命运的急转&，但另一位小提琴学者亨利*罗斯却否认这一点：他指出使海非兹人气十足的其实是他丰美的音质和极为活跃又带英雄气概和艺术气息的人格魅力----而这些特质米尔斯坦即不缺也未求。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。