转位

Because corticosteroid can modify the immunological process which is considered the major mechanism involved in AHS, it is used to treat AHS clinically. However, corticosteroid therapy may have deleterious effect (e.g., delayed healing of cutaneous lesions, infections, prolonged hospital stay). Therefore, the use of corticosteroids for AHS remains controversial. We reported a 54-year-old man who had underlying diabetes mellitus with chronic renal insufficiency, hypertension and hyperlipidemia. Allopurinol 100mg twice a day was initiated one month prior to admission. After taking the drug for 24 days, he developed a generalized mild itchy eruption on the trunk and upper extremities followed by chillness, fever, ocular discomfort and painful oral ulcer over one-week period and was admitted to the hospital. A skin biopsy revealed changes consistent with Stevens-Johnson syndrome.

本文报告一位54岁的男性患者，有高血压、高血脂、糖尿病及慢性肾脏功能不全的病史，最近发现有高尿酸血症(11.1mg/dL)而开始服用Allopurinol，在服用24日后，因为逐渐发生皮肤红疹搔痒、口腔溃疡、发烧、畏寒以及眼睛不适，一周之后到医院就医，经诊断为服用Allopurinol所造成之史帝文森－强生症候群(Stevens-Johnson syndrome)，因而在皮肤科住院接受治疗，由於病人有高血压、高血脂及糖尿病，所以入院后仅以支持疗法，并未给予全身性类固醇，然而病人之病况恶化，并有肾功能恶化，因而於住院两日后，转进肾脏科病房，在使用全身性类固醇治疗之后，病况持续改善，并在2周后出院。

Antigene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis Roberto Tonelli,Stefania Purgato,Consuelo Camerin,Raffaele Fronza,Fabrizio Bologna,Simone Alboresi,Monica Franzoni,Roberto Corradini,Stefano Sforza,Andrea Faccini,Jason M. Shohet,Rosangela Marchelli,and Andrea Pession Department of Pediatrics, University of Bologna,Sant'Orsola-Malpighi Hospital, Bologna, Italy; Department of Organic and Industrial Chemistry, University of Parma, Parma,Italy; and 3Center for Cell and Gene Therapy, Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas Abstract We developed an antigene peptide nucleic acid for selective inhibition of MYCN transcription in neuroblastoma cells, targeted against a unique sequence in the antisense DNA strand of exon 2 of MYCN and linked at its NH2 terminus to a nuclear localization signal peptide.

抗原肽核酸抑制MYCN具体表达的神经母细胞瘤细胞，导致细胞生长的抑制和凋亡罗伯托利，斯特凡Purgato ，苏埃洛卡默琳，拉菲尔Fronza ，梅奥尼博洛尼亚，西蒙娜Alboresi ，莫妮卡弗兰索尼，罗伯托Corradini ，斯特凡诺斯福尔扎，安德烈Faccini ，杰森先生Shohet ， Rosangela Marchelli ，和安德烈Pession儿科，博洛尼亚大学，圣' Orsola -马尔皮基医院，博洛尼亚，意大利；有机部和工业大学化学帕尔马，帕尔马，意大利和3Center的细胞和基因治疗，德州儿童癌症中心， Baylor医学院，得克萨斯州休斯敦摘要我们开发了一种抗原肽核酸的选择性抑制神经母细胞瘤MYCN转录细胞，针对一个独特的序列反义DNA链的第2外显子，并与在MYCN 其氨基端为核定位信号肽。

In the Grapes of Wrath Steinbeck has achieved an interesting contrapuntal effect by breaking the narrative at intervals with short, impressionistic passages recorded as though by a motion picture camera moving quickly from one scene to another and from one focus to another.

在《愤怒的葡萄》一书中，斯坦贝克不时打断故事的叙述，插进一些简练的、印象式的段落，取得有趣的对位衬托效果，仿佛是在用一架电影照相机作纪录似的，很快从一幕场景换为另一幕场景，从一个焦点转到另一个焦点。

In the Grapes of Wrath Steinbeck has achieved an interesting contrapuntal effect by breaking the narrative at intervals with short, impressionistic passages recorded as though by a motion picture came

在《愤怒的葡萄》一书中，斯坦贝克不时打断故事的叙述，插进一些简练的、印象式的段落，取得有趣的对位衬托效果，仿佛是在用一架电影照相机作纪录似的，很快从一幕场景换为另一幕场景，从一个焦点转到另一个焦点。

It's a hardscrabble life, but getting better, for Costa Rican campesinos such as this young woman in Guanacaste province.

它是非常贫困的生活，但是转好，因为哥斯达黎加农夫例如这位年轻的女人在瓜纳卡斯特省。

They had received her doubtingly, if not coolly; and nothing beyond the merest commonplace had been talked almost all the time - till just at last, when mrs. martin's saying, all of a sudden, that she thought miss smith was grown, had brought on a more interesting subject, and a warmer manner. in that very room she had been measured last september, with her two friends.

直至谈 话快要结束时，马丁太太突然话锋一转，她觉得史密斯小姐长高了，这才引出了一个比较感兴趣的话题，态度也不像先前那么冷漠了，她们呆的那间房子正是去年九月她跟她的两位朋友量过个子的地方，她们还在窗户旁的护壁板上用铅笔做了标记，并写了备忘录，那是他在上面画的，那个日子，那个时刻，那几个人，那个场合等等好像都历历在目。

When I saw a fellow student desperately trying to push her heels down at the expense of keeping her shoulders rotated back and her thighs pulled up, I sneered inwardly: Newbie!

慢慢地我的梵语说的越来越好，当我看到一位学员拼命的试图把脚后跟压下去而不惜把双肩向后转、抬起大腿时，我内心窃笑：新手。

The forward section of the blocker door is attached to the sleeve with two bolts, the blocker door drag link attaches the blocker door to the inner duct.

当外壳移动后部，阻流门转到阻流位，由于外壳转动，并且门连接在内部管道。

The 22-year-old Nigerian also has an escape clause - set at 13 million - but appears to have committed himself to the club after a controversial conclusion to his first season on Tyneside.

这位22岁的尼日利亚前锋合同中也存在着1300W的最低转会费，但是在纽卡过了一个有争议的赛季后，他表示愿意继续留队。

In this study, main chain of 4,4'-Biphenol combine different side chains to discuss polymer ~ polymer which synthesizes by the difference of structure of 1-Bromobutane、1-Bromoocatane、1-Bromododecane.To examinate luminance property and judge the correction for the structure of polymer ~ polymer by FT-IR、NMR-1H、UV、PL, in the meanwhile,to investigate into radiation wavelength under the condition of different side chains.

中文摘要 1。本实验是利用4，4'-Biphenol为起始物，与Allyl bromide反应，产生丙烯基芳基醚化合物，再利用克莱森重排反应将丙烯基转至邻位，然后在将OH基转变为不同链长的烷基醚合成出聚合物耤I），以FT-IR、NMR-1H、UV、PL测定其发光性质及判断产物结构是否正确，并探讨化合物在不同侧链之条件下，比较其放射波长。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。