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It made those company revoluted avoid confusing successfully and turning it into weak.

从而成功避免陷入许多高技术企业转之则乱，越转越弱的企业转型怪圈。

Objectives:Through the detection of the expression level of interleukins-1β(IL-1β), matrix metalloproteinase 9(MMP-9) and nuclear factor kappa B in Synovium and the detection of the concentration of IL-6 and TNF-αin serum of collagen induced arthritis Wister rat, to investigate the relationship between IL-1β、MMP-9、NF-κB and arthritis index in the development of arthritis,and to understand the pathology of synoviocyte.This may provide an experimented proof for the diagnosis of clinical rheumatical arthritis. Methods: Thirty male Wistar rats were randomly divided into two groups,namely the model controlled group and the normal controlled group,three subgroups were randomly divided in model group and controlled group separately.

目的：通过对白细胞介素1β，基质金属蛋白酶-9，转录因子核因子κB在胶原性关节炎大鼠滑膜细胞表达水平的观察，同时监测同期血清细胞因子IL-6和TNF-α的浓度，旨在探讨白细胞介素1β，基质金属蛋白酶-9，转录因子核因子κB与RA发生发展及其与关节指数之间的相关性，了解炎性病变关节滑膜细胞的病理生理状态，进一步为类风湿关节炎的临床治疗提供实验依据。

Restoration of ODC expression in the HL60-ODC cells resulted in rescue of rottlerin-induced apoptosis of HL60 cells. Simultaneously, phosphothreonine-ODC of rottlerin-treated HL60-ODC cells was highly elevated comparing with HL60-pcDNA3 cells. Taken together, we suggested that rottlerin, a PKCd inhibitor, might decrease phosphothreonine-ODC to reduce both protein stability and enzyme activity of ornithine decarbooxylase and finally resulted in cell apoptosis.

为了侦测鸟胺酸去羧化是否能够负调节rottlerin所引发的细胞凋亡，我们将具有鸟胺酸去羧化cDNA载体稳定转染至HL60细胞内，此细胞称为HL60-ODC细胞，另转染载体的细胞称为HL60-pcDNA3细胞；实验发现HL60-ODC细胞中的鸟胺酸去羧化蛋白为HL60-pcDNA3细胞与HL60细胞表现之2.5倍，同时HL60-ODC细胞提升鸟胺酸去羧化蛋白表现，能够减少rottlerin造成之细胞凋亡现象，并且此蛋白在HL60-ODC细胞中酥胺酸磷酸化较HL60-pcDNA3细胞表现高。

The Results displayed: DChanges of histological morphology in treating group is superior to the other two groups.(2Expression of BMP-2 at fracture region in treating group is obviously supeior to the other two groups(p.05) and advancely reach peak valuce at first weak.(3) transcriptional level of BMP-2 mRNA in treating group is obviously supeior to the other two groups(p.05) and samely advancely reach peak valuce at first weak.(4)In every period of fracture healing, the expression of BMP-2 and transcriptional level of BMP-2 mRNA appear dynamic change and begin to go up after fracture, moreover reached to peak value in two weaks, then go down gradually.

结果发现：(1)治疗组组织形态学检查明显优于其它二组；(2)治疗组骨折部位骨形态发生蛋白-2(BMP-2)的表达水平比其它二组明显提高(P＜0.05)，并在一周时提前达到高峰；(3)治疗组骨折部位骨形态发生蛋白-2(BMP-2)mRNA的转录水平比其它二组明显提高(P＜0.05)，同样在一周时提前达到高峰；(4)在骨折愈合的不同时期，BMP-2的表达及其mRNA的转录水平呈动态变化，即骨折后开始升高，2周左右达到高峰，以后逐渐下降。

I therefore diverted the present discourse between me and my man,rising up hastily, as upon some sudden occasion of going out; thensending him for something a good way off, I seriously prayed to Godthat He would enable me to instruct savingly this poor savage;assisting, by His Spirit, the heart of the poor ignorant creatureto receive the light of the knowledge of God in Christ, reconcilinghim to Himself, and would guide me so to speak to him from the Wordof God that his conscience might be convinced, his eyes opened, andhis soul saved.

这一路上尽是崇山峻岭，悬崖峭壁，看起来煞是可怕。可是，向导左转右转，曲折迂回，居然带着我们不知不觉地越过了最高的山头，路上并没有碰到什么大雪的困阻。突然，他叫我们向远处看，我们居然看到了风景美丽、物产丰富的朗格多省和加斯科尼剩只见那儿树木繁茂，一片葱绿，但距离还相当远。我们还得走一程歧岖艰难的山路，才能到达那儿。然而，使我们感到不安的是，这时下起了大雪，整整下了一天一夜，简直没法走路。向导叫我们放心，说我们不久即可通过这一地区。事实上，我们也发现，我们一天天地在下山，而且愈来愈往北走。

Transient responses of the tiltrotor during the transition flight are calculated aiming at semispan soft-in-plane tiltrotor models with the elastic wing.

相比常规直升机的旋翼机体耦合或飞机的螺旋桨机翼间的耦合，倾转旋翼机的各种耦合关系更复杂，特别是倾转旋翼机在两种飞行状态间的过渡过程中，系统的惯量及耦合特性相应变化，气弹耦合动力学问题尤为复杂，具有很强的非线性与非定常特性。

Chronic hepatitis ;α 2b IFN combing injection ZhuLingDuoTang ; HBeAg and HBV DNA sero conversion

慢性乙型肝炎；干扰素联合猪苓多糖； HBeAg阴转； HBV-DNA阴转

The N gene protein was expressed in the CHO cells proved by IFA. The N gene was transcripted as proved with RT-PCR. CHO/CDV-N cell strain was constructed, which provided evidence for research of CDV serumal detection and gene vaccine.

然后通过磷酸钙共沉淀法转染CHO-K1细胞，通过潮霉素筛选得到阳性克隆，间接免疫荧光实验鉴定N基因在CHO细胞中的表达，并用RT-PCR方法从转录水平证实N基因在CHO-K1细胞中的表达，最终建立了CHO/ CDV-N细胞株，为犬瘟热病毒的血清学检测和基因疫苗的研制奠定了基础。

Results After screening, 59 subtracted library clones were isolated which were specific for strain VIB72, and the DNA sequences of these clones were determined. Seventeen fragments showed high homology to the genes of known functions in other bacteria. This includes soluble lytic murein transglycosylase, mobilization protein, transposase (IS66), resistance-related protein (metallo-beta-lactamase and acetyltransferase family), toxin protein (DT-201 and alveicin A immunity protein), ATP-dependent endonuclease of OLD family like protein, SocE and GTP-binding protein HflX (high frequency of lysogenization).

通过对差减文库筛选，分离到59个对菌株VIB72的克隆，并对这些克隆的DNA序列进行了测定。17个基因片断与其它细菌的已知功能的基因有较高的同源性，其中包括可溶性溶胞壁质转糖基酶、转移蛋白MobA和MobC、转座子IS66、抑制相关蛋白（金属β-内酰胺酶和乙酰转移酶家族）、毒素蛋白（DT-201和alveicin A免疫蛋白）、与OLD 家族相似的ATP依赖性核酸内切酶以及SocE 和GTP结合蛋白HflX。

During somitogenesis, zebrafish FoxD3 is known of maintaining the somitic expression of myf5, and subsequently regulates myogenesis. FoxD5, another gene of the FoxD family, is also expressed in forming somites of the anterior PSM. However, the regulatory function of FoxD5 in somitogenesis is not clear.

虽然已知斑马鱼中FoxD3在体节发育时，能维持myf5在体节的表现并藉此参与於肌肉的发育；但FoxD转录因子家族中的另一员，FoxD5，在体节发育时也会表现在presomitic mesoderm前端生成中的体节处，而这个FoxD转录因子是否在体节发育的过程中扮演调控的角色目前仍不清楚。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。