超声的

Objective To evaluate the curative effect of high intensity focused ultrasound in liver cancer therapy and the applied value of ultrasound in the evaluation.

目的评价高强度聚焦超声治疗肝癌的疗效及超声在疗效评价中的应用价值。方法HIFU治疗肝癌患者78例，通过术中实时超声监控及治疗前后彩色多普勒超声对比评价治疗效果。

The influence of the main process variables, including the time of osmotic dehydration, the time of ultrasound field treat and the intensity of ultrasound field on water loss, solid gain, weight reduction and relative conductivity of sarcocarp cell membrane were investigated.

对超声场强化龙眼果肉渗透脱水进行研究，探讨渗透脱水时间、超声处理时间、超声场强对物料脱水率、失重率、固形物得率、细胞膜透性等的影响；建立超声场强化龙眼渗透脱水的经验动力学方程。

Methods:to analyze electrocardiogram,echocardiogram,left ventriculography,nuclear magnetic resonance results of 13 cases with ahcm.results:12 cases had apical wall thickening in echocardiogram, 3 cases had a "spade-like" configuration on left ventriculogram, 7cases were misdiagnosed as coronary heart disease initially.conclusion:ahcm is easy to be misdiagnosed as coronary heart disease, echocardiogram plays important role in the diagnosis of ahcm, in patients with suspicion of ahcm and inadequate echo images, the use of contrast echocardiography or mri should be considered.

对13例ahcm的心电图、超声心动图、左室造影及磁共振结果进行分析。结果：13例ahcm中心电图有特征性改变12例，超声心动图提示心尖区增厚12例，左室造影提示舒张期呈"黑桃"形改变3例，初诊误诊为冠心病7例。结论：ahcm易被误诊为冠心病，超声心动图是诊断该病的重要手段，必要时可做心脏超声造影术或磁共振检查。

UV and SMPE-GC-MS results confirmed that radical-oxidation and hightemperature pyrogenation controlled the sonochemical-oxidation of toluene, and mainmiddle-products included benzaldehyde, bibenzyl, dibutyl phthalate, et al., final products werecarbon dioxide and water. The reactive violet K-3R was chosen as a model compound to study the effect ofsonoelectrochemical degradation of nonvolatile pollutant.

以超声与电化学作用处理活性紫K-3R水样，二者协同效应明显，5V槽电压时60min K-3R脱色效率要比纯电场作用时高57.8％，纯超声场对活性紫基本无显著的降解作用，初始浓度、pH对超声电化学协同降解影响较大，实验建立了活性紫降解的动力学模型，经超声电化学处理后，K-3R共轭发色体系已基本被破坏，但溶液中仍有苯环等产物。

Objective:to explore the evaluation of color doppler ultrasonography in differential diagnosis of renal cystic disease.methods:theultrasonographic finds of cystic renal cancer in 4 cases,renal cyst in 30 cases, renal tuberculosis in 3 cases,nephropyosis in 8 cases,renal hydatid in 2 cases were analyzed.compared with each other in size,shape,edge, echo of cyst wall and cyst water,intracapsular membrane,blood flood.results:two-dimensional and color ultrasonography are helpful in showing the characteristic of structure and blood flow.the signal of blood flow can be found in cystic wall.node of cystic wall and intracapsular membrane of cystic renal cancer.the rate ofintracapsular membrane and node of cystic wall is higher than nephropyosis,renal tuberculosis and cystic renal disease.

目的：探讨彩色多普勒超声在肾脏囊性病变鉴别诊断中的价值。方法：对临床和病理证实的4例囊性肾癌，8例肾脓肿，2例肾包虫，3例肾结核，30例肾囊肿的二维超声及彩色多普勒超声表现进行了分析，对每例病灶的大小、形态、边界、囊壁回声、囊液回声、囊内分隔及彩色血流的有无、性质进行比较。结果：二维超声和彩色多普勒超声可以反映肾脏囊性病变的结构特征及血流特征。

Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

成果包括：（1）在生物组织弹性成像方面，研究了多种图像校正方法和应变估计方法，进行了弹性重构和仿体、离体及在体超声弹性成像实验研究；（2）在生物微系统和微血管血流灌注成像方面，制备了三种不同包膜超声造影微泡，研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制，并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究；（3）在阵列式高强聚焦超声治疗与监控成像技术方面，设计制作了新的HIFU换能器，解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题，并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展，具有重要应用前景；（4）在语音听觉系统特别是嗓音康复方面，研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理，建立基于神经、肌肉和空气动力系统的综合补偿调节模型，提出了相应的评价系统。

Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

中文摘要：成果包括：（1）在生物组织弹性成像方面，研究了多种图像校正方法和应变估计方法，进行了弹性重构和仿体、离体及在体超声弹性成像实验研究；（2）在生物微系统和微血管血流灌注成像方面，制备了三种不同包膜超声造影微泡，研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制，并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究；（3）在阵列式高强聚焦超声治疗与监控成像技术方面，设计制作了新的HIFU换能器，解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题，并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展，具有重要应用前景；（4）在语音听觉系统特别是嗓音康复方面，研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理，建立基于神经、肌肉和空气动力系统的综合补偿调节模型，提出了相应的评价系统。

Cases with renal transplantation were performed with dynamic state CDFIin Ultrasound Dept. of Nan fang Hospital from April, 2005 to October, 2006. Theexamine time is respectively after operation in three days, seven days, one month andthree months. Before operation examine the condition of uropoiesis function such as apair of kidney, ureter, bladder and cardiac function. After operation reexamine thecondition of cardiac function once again, and examine TK detailed and completely:First, using two-dimensional imaging to observe the shape and the volume of the TK.Secondly, using Color Doppler to observe the renal artery and each artery inside theTK. Finally, using pulsed Doppler to measure the peak systolic velocity, enddiastolic velocity and resistance index.

对南方医科大学南方医院超声诊断科自2005年4月～2006年10月对152例同种异体肾移植患者进行动态CDFI监测，超声检查时间分别为术前与术后3d、术后7d、1个月及术后3个月，术前超声检查双肾、输尿管、膀胱等泌尿系功能情况及心脏功能情况，肾移植术后再次对心脏功能情况进行跟踪复查，并对移植肾进行详尽检查：先用二维超声观察移植肾的形态、大小，随后应用CDFI观察移植肾动脉及肾内各级动脉的血流充盈情况，最后用脉冲式多普勒测量收缩期峰值流速、舒张末期流速、阻力指数。

Methods:to analyze electrocardiogram,echocardiogram,left ventriculography,nuclear magnetic resonance results of 13 cases with ahcm.results:12 cases had apical wall thickening in echocardiogram, 3 cases had a "spade-like" configuration on left ventriculogram, 7cases were misdiagnosed as coronary heart disease initially.conclusion:ahcm is easy to be misdiagnosed as coronary heart disease, echocardiogram plays important role in the diagnosis of ahcm, in patients with suspicion of ahcm and inadequate echo images, the use of contrast echocardiography or mri should be considered.

对13例ahcm的心电图、超声心动图、左室造影及磁共振结果进行分析。结果：13例ahcm中心电图有特征性改变12例，超声心动图提示心尖区增厚12例，左室造影提示舒张期呈&黑桃&形改变3例，初诊误诊为冠心病7例。结论：ahcm易被误诊为冠心病，超声心动图是诊断该病的重要手段，必要时可做心脏超声造影术或磁共振检查。

It has been found that the process parameters, the spindle speed, the ultrasonic vibration power as well as the gap between the magnetic pole and the work piece surface, were the key factors in deciding the finishing quality and efficiency of the UMAF.

在研究超声磁粒复合研磨工作原理基础上，结合传统磁粒研磨材料去除数学模型，探讨了超声振动对提高磁粒研磨效率的积极作用，揭示出主轴转速、供磁电流、加工间隙、超声功率等是影响超声磁粒复合研磨质量和效率的关键因素。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。