超兴奋性

The hyperexcitability of spinal dorsal horn neurons is one of the main reasons for persistent pain.

脊髓背角神经元超兴奋性被认为是病理性疼痛发生的重要原因。

Methods On the basis of bilirubin induction and NMDA receptor an-tagonist GAPA administration in guinea pigs. The brain extracellular EAA neurotransmitter was ex-tracted with microdialysis and analysed with HPLC; then, brain tissue ATP was measured by fluores-cence assay and intracellular Ca2 + was measured by fluorescence imaging analysis.

制作胆红素脑病动物模型基础上，在体脑内微透析提取兴奋性氨基酸神经递质，HPLC检测天冬氨酸、谷氨酸、甘氨酸，并给予模型动物NMDA受体拮抗剂GAPA干预，电镜检测脑组织超微结构，荧光检测脑组织ATP与细胞内Ca2+含量。

Methods The global cerebral ischemia/reperfusion injury model was established by the four-vessel occlusion (4VO) method, and then the model animals sere given high-middle-and low-dose muscone. Meanwhile, sham-operation group, model group, and positive control group were also set up. The rats neuroethology behavior, and the contents of superoxide dismutase, malondialdehyde and excitatory amino acid in is-chemic brain tissue were examined.

取Wistar大鼠，采用四血管阻断(4VO)法制备全脑缺血再灌流损伤模型，将成模大鼠随机分为麝香酮高、中、低剂量组(3.6， 1.8， 0.9 mg/kg)，并设假手术组，模型组，阳性对照药尼莫地平组(10.8 mg/kg)，共6组，每组12只对大鼠神经行为学，缺血区脑组织超氧化物歧化酶，丙二醛含量，脑组织兴奋性氨基酸含量进行检测。

Recordings of the action potential of peroneal nerve trunk showed that the slow conduction fibers (＜1m/s) could be activated by the stimulation of SPN with a current intensity of 300μA, but not of DPN.

细胞内记录的资料显示，刺激PF或dPAG也引起几种不同的反应：①有兴奋性突触后电位和动作电位，并有兴奋后超极化现象；②在AP前有超极化现象；③只有EPSP和AP，无明显的兴奋后超极化。

Results: Among 32 tested MNs, depolarizing responses(excitatory postsynaptic potential, EPSP) were elicited by cVLF stimulation in 21 MNs, hyperpolarizing response (inhibitory postsynaptic potential, IPSP) in 1 MN, and IPSP preceded by EPSP in 4 MNs. The cVLFEPSPs were stimulus intensity-dependent, and could be abolished by low Ca(superscript 2+)/high Mg(superscript 2+) solution. compared with iVLF-EPSPs, cVLF-EPSPs showed longer latency (P.001). The cVLF-IPSP presented with membrane potential-dependent property and was eliminated by the perfusion of picrotoxin (30 μmol/L) and strychnine (1.0 μmol/L).

结果：在32个测试的MNs，观察到cVLF电刺激可在21个MNs上诱发去极化反应（即cVLF性兴奋性突触后电位，cVLF-EPSP），在1个MN上诱发超极化反应（即cVLF性抑制性突触后电位，cVLF-IPSP），在4个MNs上诱发cVLF-EPSP后复合有cVLF-IPSP的反应。cVLF-EPSP具有刺激强度依赖性、被低钙高镁溶液取消的特性，与i VLF性EPSP相比，有潜伏期较长的特点(P.001)。cVLF-IPSP呈膜电位依赖性，并被印防己毒素(30μmol/L)及士的宁(1.0μmol/L)取消。

Objective To study the clinical manifestation and significance of facial nerve overexcitability at the beginning of facial paralysis.

目的 探讨面瘫初期面神经呈现超兴奋性的临床表现及意义。

Facial nerve of the sick side presenting overexcitability belongs to the natural curative group of physiological conduction block.

呈超兴奋性的患侧面神经属生理性传导阻滞的自然治愈群。

Overexcitability group included67cases whose threshold differences were over-1.57mA.

呈超兴奋性的患侧面神经属生理性传导阻滞的自然治愈群。

Sinus bradycardia or sinus bradycardia with arrhythmia,sino-auricular block,sinus stopping beat with junctional abnormal beat occurred in15cases;Sinus bradycardia with ST-T changes occurred in10cases,ab-normal excitation（including ventricular,supraventricular premature beat with tachycardia）occurred in6cases the cardiac function of9cases were checked up:stroke volume,cardiac indexand ejection timewere normal or on the low side.

窦性心动过缓或窦性心动过缓伴不齐、窦房传导阻滞、窦性停搏伴交界性异搏共18例；窦性心动过缓伴ST-T改变11例；兴奋性异常（室性、室上性早搏伴心动过速）6例。9例心功能检查：心输出量、心脏指数、射血分数三项指标在正常偏低水平。3例心脏彩超三尖瓣赘生物，诊断为感染性细菌性心内膜炎。

Sinus bradycardia or sinus bradycardia with arrhythmia,sino-auricular block,sinus stopping beat with junctional abnormal beat occurred in15cases;Sinus bradycardia with ST-T changes occurred in10cases,ab-normal excitation（including ventricular,supraventricular premature beat with tachycardia）occurred in6cases the cardiac function of9cases were checked up:stroke volume,cardiac indexand ejection timewere normal or on the low side.The colour Doppler showed that excrescence in tricuspid valve of3cases and the diagnosis was infectivity bacterial endocarditis.

窦性心动过缓或窦性心动过缓伴不齐、窦房传导阻滞、窦性停搏伴交界性异搏共18例；窦性心动过缓伴ST-T改变11例；兴奋性异常（室性、室上性早搏伴心动过速）6例。9例心功能检查：心输出量、心脏指数、射血分数三项指标在正常偏低水平。3例心脏彩超三尖瓣赘生物，诊断为感染性细菌性心内膜炎。

The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0，0.4，0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗，测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

By analyzing theory foundation of mathematical morphology in the digital image processing, researching morphology arithmetic of the binary Image, discussing two basic forms for the least structure element: dilation and erosion.

通过分析数学形态学在图像中的理论基础，研究二值图像的形态分析算法，探讨最小结构元素的两种基本形态：膨胀和腐蚀；分析了数学形态学复杂算法的基本原理，把数学形态学的部分并行处理理念引入到家实际应用中。