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A series of pyridazino[3,2-c]1,2,4-triazoles were synthesized from hydrazides and 3-aryl-6- chloro pyridazine s (3a~3d), which were obtained from substituted benzene and succinic anhydride by Friedel-Crafts reaction, cyclization with hydrazine hydrate, dehydrogenation and chloro-substitution.

以取代苯和丁二酸酐为起始原料,经Friedel-Crafts反应,肼合环,Br2/HOAc氧化脱氢后得到一系列1,6-二氢-3-芳基-6-哒嗪酮(2a~2d)。然后将2a~2d与PCl5在POCl3中回流,得到相应的氯代产物3a~3d,将其与酰肼作用,合环后得到一系列未见报道的哒嗪并[3,2-c]1,2,4-三唑类化合物。所有化合物结构均经元素分析,IR,1HNMR和MS谱得以证实,并对其波谱性质进行了讨论

The oscillating behaviors in darkness of pyrogallic acid-KBrO-HSO-system have been studied, the relations between induction period τ as well as oscillating period and the initial concentrations of reactants of the system have been determined experimentally at 25℃、35℃.

研究了无光照条件下焦性没食子酸-KBrO-HSO体系振荡的基本规律,得到了25℃、35℃时起振时间τ、振荡周期T与各反应物起始浓度之间关系的经验方程。

Plain clothes and fine and smooth and particulate, mainly due to quadrochromatic of granula and finely and making that magnification and subtle stressed the value of the start effect, registral.

平服细腻性与颗粒性,主要由原稿的颗粒细腻程度所决定,也受放大倍率和细微强调起始作用值的制约。

Furthermore, the pattern of neural activity seems to be stable when the rivalrous stimuli are presented intermittently, which is known to induce stable perception in human.

研究结果显示,在有适当起始时间差的竞争性刺激下,后续刺激的作用会被先导刺激所抑制。

Ornithine decarboxylase, a rate-determining enzyme of the polyamine biosynthetic pathway, is involved in the control of cell cycle, differentiation, cell growth and apoptosis. Previous studies described that protein kinase Cd regulates ODC activity. In this thesis, human leukemia cell line, HL60 cell, was used for the treatment with a specific PKCd inhibitor, rottlerin, to measure the effects on cell growth.

鸟胺酸去羧化(ornithine decarboxylase,ODC)为多胺酸起始与决定反应速率的酵素,对细胞周期、细胞生长、分化及细胞凋亡扮演一重要角色;在寻找肿瘤治疗及预防药物研究中,纯化植物天然物质是其中来源之一,研究者筛选药物时,测定对鸟胺酸去羧化活性是否具抑制效果是一个重要的试验。

The screening method of seven alleles (Z-6,Z-4,Z -2,Z,Z+2,Z+4 and Z+6) in then dinucleotide tandem repeat sequence was st udied. These alleles constitute a microsatellite DNA marker upstream of the tran scription initiation site on the aldose reductase gene.

湖南医科大学学报000103 摘要:研究了醛糖还原酶基因转录起始点上游-2.1kb处的微卫星DNA标记--n二核苷酸串联重复序列7种等位基因(Z+6,Z+4,Z+2,Z,Z-2,Z-4和Z-6)的筛选方法。

The screening method of seven alleles (Z-6,Z-4,Z -2,Z,Z+2,Z+4 and Z+6) in then dinucleotide tandem repeat sequence was st udied. These alleles constitute a microsatellite DNA marker upstream of the tran scription initiation site on the aldose reductase gene.

研究了醛糖还原酶基因转录起始点上游-2.1kb处的微卫星DNA标记--n二核苷酸串联重复序列7种等位基因(Z+6,Z+4,Z+2,Z,Z-2,Z-4和Z-6)的筛选方法。

It was iound in the experiment that the glass fiber made crystal peak temperature raise 8~9 ℃, Crystal original taper to be large, spherocrystal size small, it -acted the function of hetero-geneous nucleation for polypropylene . High density polyethylene has plasticizing efficancy and combined effect of hetero-geoeous nu...

试验表明PP/GF/HDPE复合物的结晶峰温度升高8~9℃,结晶起始斜率变大,球晶几何尺寸明显减小,复合物中的玻璃纤维起到异相成核作用,高密度聚乙烯对聚丙烯有增塑作用并对异相成核具有协同效应。

Described in chapter 3 is the immediate application of the Clemmensen reductive rearrangement reaction to the polycyclic system as illustrated in a elaboration of the 5-6-7 tricyclie core skeleton of Stemona alkaloids in 5 steps: N-alkylation, [3, 2] -sigmatropic rearrangement, Dieckmann condensation, oxidative cyclization, reductive rearrangement, starting from ethyl pipecolinate hydrochloride.

我们以哌啶酸乙酯为起始原料,经氮烷基化,[3,2]-σ重排,Dieckmann缩合,自由基环化,6-6-6元环系到5-6-7元环系的还原重排五步反应,高收率地构筑了百部生物碱的5-6-7氮杂三环骨架,并用X射线晶体衍射法确定了其结构。

The target compound was cut off from the middle of the two benzene ring of Biphenyl Tetrazole and the key step was accomplished through Suzuki Coupling reaction.

第二部分:抗高血压药物——缬沙坦的新合成路线研究我们分别以对溴甲苯,对溴苄溴和对溴苯甲醛为起始原料分三条路线完成了缬沙坦的全合成。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。