起作用

In this paper, the effects of enrofloxacin residues on soil ecological processes (soil respiration, soil cellulosic decomposition, soil ammonification , and soil nitrification) were studied.

1μg/ g土对土壤氨化作用有刺激作用，而较高浓度恩诺沙星残留(1μg/ g土，10μg/ g土)则会对其起抑制作用，药物作用活性期为 9d；不同浓度恩诺沙星对土壤硝化作用影响极其显著，当恩诺沙星浓度达到 1μg/ ml时，在 3～ 9d内，对土壤硝化作用有一定抑制作用。

It is necessary to point that in the context of the dominant legal tradition,the function and status of statute law and case law are different in practice in civil law countries and Anglo American ...

由于起主导作用的法律传统的影响，成文法和判例法在两大法系国家法制完善的具体过程中所起的作用与地位是有所不同的。

The plasticity in a bas-relief is such that the features of a face in it can be prominent in both a convex and concave manner; what matters is that the extreme features are emphasized.

在一个可塑性的浅浮雕中也是如此，在那上面起着重要作用的脸部可以是凸的和凹的两个风格；所有起着极度重大作用的实质是强调音。

The long-term opening of mitochondria permeability transition pore results in the release of cytochrome C, apoptosis inducing factors, Ca2+ and other apoptosis factors into cytoplasm, which can destruct the whole cell structure and function by activating the main member of apoptosis protein family——caspase, or destroying the intranuclear chromoplasm independently, or affecting other protein relying on Ca2+, and finally lead to the formation of apoptotic body.

线粒体是真核生物能量和代谢的中心，也是细胞凋亡信号传导途径中起关键作用的细胞器，越来越多的研究表明，在凋亡信号的刺激下，线粒体发生膨胀，其外膜膜电位降低，外膜破裂后释放出膜间隙的诸多凋亡效应因子，在细胞凋亡中起着主开关的作用。

1Niche construction can lead to stable coexistence of diverse genotypes in spatially structured population, which supports a stable polymorphism even without heterozygote superiority.(2)With habitat deterioration, niche construction accelerates the formation of steady polymorphism and hence impedes the harmful influences of environment on the population, which might embody a life-history strategy of organism under the unfavorable environment.(3)Niche construction results in the coexistence with alternative polymorphism through genotype-environment feedback and limited gene flow.(4)The niche-constructing organism is an active force to alter its environment and hence the direction of natural selection in order to better survival.(5)Spatial dynamics and distribution pattern of metapopulation are profoundly influenced by time-lagged niche construction.(6)Metapopulation size can reach a fixed level in the recency effect and equal weighting of time lag but is statistical stability in primacy effect, which implies the primacy effect is most remarkable.(7)The increment in the relative weightingof each generation\' niche construction and the length of time lag are significant factors for system destabilization.(8)Moderate capacity of positive niche construction benefits the metapopulation persistence.(9)The narrowing of niche breadth can decrease the metapopulation size and thereby increase the extinction risk.(10)The coupled function of time lag and niche construction make the system oscillation and generate the spiral wave, spiral-broken and circular wave in heterogeneous habitat.The spatial distributions of metapopulation and resource content are complementary due to a phase lag of their both frequencies.(12)Metapopulation persistence with niche construction depends not only on the balance between colonization and extinction, but also on the balance between the ability of niche construction and natural dissipation of habitat.(13)Metapopula-tion can survive under certain condition when the percent of suitable patches in habitat is lower than the ration of extinction to colonization.(14)Two thresholds exist in the process of transition of habitat quality dynamics from unsuitable to suitable, which include the intensity of niche construction and the initial condition of system.(15)Metapopulation size is positive correlated with the ability of positive niche construction, which means that organism or population who has strongly positive influences on their environment plays an important role to maintain the available habitat.

通过上述几个方面的研究，主要得出以下15条结论：(1)生态位构建可使空间结构种群，甚至是在没有杂合子优势的条件下，形成多种可能的稳定基因型分布模式；(2)随着环境的破坏与恶化，种群的生态位构建作用加速其较早形成稳定多态以阻碍环境对种群的不利影响，解释了有机体在不利环境下的一种生活史对策；(3)生态位构建作用通过基因型—环境反馈机制及有限的基因交流导致基因型多态的稳定共存；(4)有机体的生态位构建作用是一种积极的动力改变环境进而改变其自然选择的方向；(5)生态位构建的时滞作用对集合种群动态和空间分布产生深刻影响；(6)集合种群大小在时滞的崭新效应和等权重效应下达到一固定值，而在首位效应下达到统计稳定，表明首位效应的影响最显著；(7)首位效应下生态位构建相对权重的增量和时滞的长度是影响系统不稳定性动态的关键因素；(8)适中的生态位构建强度有利于集合种群的续存；(9)生态位宽度变窄会减少集合种群的数量从而增加其灭绝风险；(10)时滞和生态位构建的双重作用使系统产生周期振荡，并在异质性环境中产生稳定的螺旋波，破碎的螺旋波和环形波三种分布模式；(11)集合种群与资源含量的空间分布因为相滞而互补；(12)具有生态位构建的集合种群续存不仅取决于侵占率与灭绝率之间的平衡，而且依赖于生态位构建能力同其生境的自然消耗速率之间的妥协；(13)当生境中适合侵占的斑块比例小于其侵占率与灭绝率之比时，生态位构建作用促使集合种群在一定条件下续存：(14)生境斑块的状态从不适合到适合转变过程中存在生态位构建强度和系统初始条件这两个阈值；(15)集合种群的大小同正生态位构建能力正相关，意味着对环境具有较强正作用的有机体对维持有效生境起积极作用。

DCs acquired by our reformed methods express both CD83 and CD 14 molecules highly, and have a higher density than other domestic reports. The higher TNF in DCs culture medium of HC patient suggests DCs in patient still have antigen presenting ability and by optimization the culture medium would improve its presenting ability and have a potential value in design and application individual vaccine. Although antigens pulsed DCs have a decrescent antigen presenting ability but BCG HSP70 could induce its mature and improve its presenting ability. Suggests BCG HSP70 would be a useful mature inducer. Lymphocytes primed by DCs based HC vaccine have the specific cytotoxicity against HCC lines. The CTL after freezing and anabiotic could prophylaxis and therapy HC xenograft on nude mouse. The results also suggests that CD4〓 lymphocytes play a important role in HC with a good differentiation and would be useful in treatment this kind of HC. After being activated by Peptide LLNQHACAV of hAFP and apoptotic HCCs pulsed DCs respectively, the culture medium of activated lymphocytes both contains a high level Th1 cytokines IL-12 and TNF. Primed lymphocytes appeared a characteristic of NK cells. DCs not only inhibited the growth of human HCC and other cancer cells in vitro but also prevented the growth of HC xenograft on nude mouse in vivo. There are at least three kinds of mechanism playing important role in DC based vaccine ,there are inhibition of DCs, HC specific CTL and cytokines pathway.

诱导出的DC共同表达CD83和CD14分子，CD83分子表达明显高于国内报道；肝癌患者DC培养上清中TNF水平高于健康人，提示肝癌患者DC仍具一定的抗原呈递能力，适当调控可使其行使APC功能，以期在肝癌个体化疫苗中发挥作用；DC负载肝癌可溶性抗原后，抗原呈递能力降低，BCG HSP70可促进DC成熟，增加其抗原呈递能力，预示BCG HSP70有可能成为促进DC活化和成熟的另一重要分子；肝癌DC疫苗在体外诱导肝癌特异性淋巴细胞，活化的淋巴细胞在体外对肝癌细胞的杀伤以特异性CTL为主，同时分泌较高水平Th1型细胞因子IL-12和TNF，并抑制4种肝癌细胞生长；冷冻复苏后的肝癌特异性淋巴细胞可以预防和抑制人肝癌裸鼠皮下移植瘤，提示DC负载肝癌可溶性抗原后诱发的MHC-Ⅱ类限制性CD4〓T细胞有可能在分化程度高的肝癌治疗中发挥作用；用DC和HLA-A2〓DC分别负载凋亡肝癌细胞和hAFP218-226位LLNQHACAV HLA-A2限制性九肽，在体外诱导肝癌特异性淋巴细胞，活化后的CTL细胞分泌较高水平的Th1型细胞因子IL-12和TNF，并具较强杀伤活性，此CTL同时具备NK细胞特征；DC对肿瘤细胞的抑制作用可能是通过吞噬实现的，Fas-L在DC抑制中也起一定作用；DC对人肝癌裸鼠皮下移植瘤的抑制率为97％；在肝癌DC疫苗的作用中，至少联合3种以上机制，即通过DC的直接作用、肝癌特异性CTL和细胞因子途径直接或间接地杀伤和抑制肝癌细胞。

The most heavy flow ability of barrage swirl is controlled by fastenning device and barrage size, the most heavy discharge is more when barrage aperture is bigger, the influence of barrage position on discharge is not obvious; The pressure of the end of the shaft and fastenning device increases which aroused by barrage, and there is a restraining action to flow waving of the shaft; The barrage aperture is smaller, the increase of pressure is heavier, the influence of position to the increase of pressure is not obvious; The positive pressure of the level section in the hole between fastenning device and barrage increases obviously, the change of press along length reduces, mural press in the hydrosphere separating area of outlet of fastenning device becomes positive pressure, which is propitious to the increase of flow cavitate number in the low pressure area of the outlet of fastenning device; The influence of change of swirl cavum diameter caused by barrage to ventilating state is obvious.

阻塞旋流最大泄流能力由起旋器及阻塞体型共同控制，降低了泄洪洞的泄流量，孔径大的阻塞最大下泄流量较大，阻塞位置对泄流量的影响不明显；阻塞引起竖井及起旋器端头压力增大，对竖井部分的水流波动具有抑制作用；阻塞孔径越小，压力增加越大，位置对压力增大影响不明显；起旋器与阻塞之间水平洞段的止压力明显增加，沿程压力变化减小，起旋器出口的水气分离区壁面压力变为正压力，有利于起旋器出口低压区水流空化数的提高；阻塞引起的旋流空腔直径变化对通气状态产生明显影响。

When the fault throw is relatively small, the shale gouge ratio and clay smear potential are relatively large and shale smear is strong. In addition, the coal layers on both sides of the fault are mainly juxtaposed against shale. Therefore, shale smear and juxtaposition play a key role in the sealing. In contrast, when the fault throw is relatively large and shale smear is relatively weak, juxtaposition is unfavorable for sealing. However, the mylonite resulted from strong cataclasis can act as a seal of the coals. The cementation resulted from underground water activity is of great significance to the sealing ability of the fault. Mylonitic coal layers resulted from faulting occur on both sides of the fault. They are unique reservoirs with low permeability and high displacement pressure and their scales depend, to some extent, on the fault throw, fault properties, the hanging wall and footwall.

结果表明：①当断层落差较小时，断层泥比率和泥岩涂抹潜势值较大，泥岩涂抹效应强烈，且与断层两侧煤层对接的岩石主要为泥岩类，此时起封闭作用的主要为泥岩涂抹作用和断层两侧岩性配置关系；②当断层落差较大，泥岩涂抹作用较弱时，对接越不利于封闭形成，但碎裂作用强烈，沿断层两侧形成的糜棱岩对煤层起到了封闭作用；③地下水活动导致的胶结作用对整个断层的封闭具有重要的意义；④断裂作用形成的糜棱煤沿断层两侧分布，此糜棱煤带是一种低渗透、高排替压力的特殊储层，其规模与断层的落差、性质、上下盘都有一定关系。

In the development of human history,it mingles with natural science.

哲学社会科学作为人类科学体系的重要组成部分，对社会发展和人类文明有着重要的推动与导向作用；在人类历史的发展中，与自然科学彼此交融，不仅起着&车之轮、鸟之翼&的作用，而且起着&车之头和鸟之脑&的作用，成为区域经济与社会全面协调可持续发展的&引擎&。

Study shows that compaction and cementation can play a destructive role in Suining formation reservoir,while dissolution and fracturing can play a constructive role in that.The main facies of Suining formation are ferruginous-shale film,anhydrite,dolomite and calcite.The micro-fracture and grain-edged fracture mainly resulted from compaction fracturing,compaction slipping and tectonic dynamic force greatly improve the reservoir permeability.

研究表明：①对遂宁组储层起破坏作用的是压实作用、胶结作用和交代作用，而溶蚀作用、压裂作用则对储层起到建设性作用；②遂宁组最主要的成岩相组合为铁泥膜－硬石膏－白云石－方解石成岩相；③由压实破裂、压实滑动和构造动力形成的微裂缝、粒缘缝有效改善了储层的渗透性。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。