败血症

Results: The attack rate of acquired septicemia was 9.99%.

结果：ICU获得性败血症的发病率为9.99%，感染者多存在败血症的易感因素。

Standard treatment for septic shock includes antibiotics, intravenous fluids and vasopressor medicines (drugs to increase blood pressure)," explained the first study's lead author, Dr. Charles Sprung, director of the general intensive care unit, department of anesthesiology and critical care medicine at Hadassah Hebrew University Medical Center in Israel."Until our study, doctors in hospitals around the world were also routinely using steroids as adjunct therapy to help hundreds of thousands of patients in septic shock fight for their lives. Our study demonstrates that this adjunct therapy of hydrocortisone is not helpful for most patients with septic shock and, in fact, may be harmful.

标准的败血症性休克治疗包括抗生素、静脉补液和血管升压药物，"第一作者，以色列Hadassah Hebrew 大学医学中心麻醉学部与危重症医学部综合加强监护单元主任Charles Sprung博士解释道，"在我们的研究之前，全世界的医生常规使用类固醇激素辅助治疗成千上万的败血症性休克患者，但是我们的研究证实了氢化可的松对多数患者并没有辅助治疗的作用，实际上可能是有害的。

RESULTS The Gram-positive cocci were 135 cases in 207 caes patients of bloody infection (56.2%). The proportion of opportunistic pathogens rose (P＜0.05 or P＜0.01). The incidence of children was higher than adult (58:42). The infant of ＜1 year was 36.2%. The newborn of＜30d was 31.4%.192 cases patients(92.8%) had protopathy or complicating diseases. No-normal birth was important susceptible factor to nowborn of bloody infection. The septicemia of Gram-negative bacillus, nowborn of no-normal birth and other septicemia of be accompanied by severe disease were main cause of death in our guoup.

结果 207例血液感染以G＋球菌为主(56.2％)，且条件致病菌感染有增多趋势(P＜0.05或P＜0.01)；儿童发病显著高于成人(58：42)，其中＜1岁婴幼儿占36.2％，＜30d新生儿占31.4％；192例(92.8％)有原发病或夹杂病；非正常生产已成为了新生儿血液感染的重要易感因素；G－杆菌败血症、不正常分娩新生儿以及伴有严重疾病的其他败血症患者是本组病例的主要死亡原因。

Although cholestasis of sepsis is often associated with gram-nagetive bacterial infection,it also occurs with a diverse array of other organisms,including Gram-positive bacteria,rickettsial,parasitic and fungal infections.in one study of bacteraemic patients with positive blood cultures only 34% had bilirubin levels greater than or equal to 2.0mg/dl.moreover,in clinical practice the frequency and extent of liver enzyme abnormalities in bacteraemic patients may be far greater than the occurrence of hyperbilirubinaemia.cholestasis appears to be a marker for the severity of sepsis,and prolonged and unresolved cholestasis carries a high mortality.

虽然败血症（sepsis引发的胆汁郁积往往与革兰氏阴性菌（gram-negative bacterial，原文negative瓶错了）感染，它也可能伴随各种各样其他的有机体，包括革兰氏阳性菌（Gram-positive bacteria），立克次体属微生物，寄生虫和真菌感染。一个对菌血症（bacteremic，原文中拼错了）的阳性患者的血液培养分析研究发现其中只有34％的胆红素水平大于或等于2.0mg/dl。而且，在临床实践中的血症患者肝酶异常的发生频率和严重程度可能远远大于高胆红素血症（hyperbilirubinemia，原文中拼错了）。胆汁郁积似乎是一个患有严重性败血症的标志，而且长期的和没有根治的胆汁郁积有很高的死亡率。

Objective and Methods To evaluate mechanisms of drugs commonly used in the treatment of septicemia, giving antibiotics including Minocycline (10 mg/kg), Clindamycin (10 mg/kg), Cyclosporin (15 mg/kg) and Platonin (10 mg/kg) to septicemic rat injected with LPS. Clinical improvement, blood pressure, heart rate, survival time are assessed, and the amount of endogenous NO production is determined.

本实验之目的是要探讨在临床上常用於治疗败血症的数种药物，可能的作用机转；藉由注射老鼠LPS模拟败血症前，先给予Minocycline，Clindamycin，Cyclosporin，Platonin等药物治疗，评估药物的改善状况，同时观察血压、心跳、动物存活时间及侦测体内NO的生成量，来比较给药与否之差异，且针对变化的可能原因来探讨。

Regionai lymphadenitis;Septicemia without an evident bubo septicemic plague

局部淋巴腺炎；没有明显淋巴腺炎的败血症败血症型鼠疫

Based on Jilin local pig streptothrix popular strains, we have chosen the representative F6 strain to be proceeded completely characteristic authenticates, which can provide consult data for research of manufacture of polyvalent inactivated vaccine.At present, there are reports of pig streptothrix in America, England, France, Russia, Japan, India, Denmark, Canada etc.

目前，美国、英国、法国、俄罗斯、日本、印度、丹麦、荷兰、加拿大等国均有关于猪链球菌分离鉴定及血清型分型的报道，从患败血症和脑炎的猪体内分离的链球菌主要是R群的猪链球菌H型，和S群的猪链球菌I型，只有少数C群、D群和L群引起心内膜炎和败血症的病原菌。

Hauser, MD, professor of pediatrics at Georgetown University in Washington, D.C., noted that pediatric trials of aPC are underway, but he is skeptical about its potential benefits in children with sepsis."Peds are a low-risk group. They tend to survive sepsis better ."

Hauser博士表示，aPC应用于小儿科的临床试验仍在进行中，但他很怀疑将aPC用于治疗败血症儿童会有什么好处，因为幼童本身即是低风险的族群，他们本来就比罹患败血症的成人容易存活。

Hauser, MD, professor of pediatrics at Georgetown University in Washington, D.C., noted that pediatric trials of aPC are underway, but he is skeptical about its potential benefits in children with sepsis."Peds are a low-risk group. They tend to survive sepsis better ."

Hauser博士表示，aPC应用於小儿科的临床试验仍在进行中，但他很怀疑将aPC用於治疗败血症儿童会有什麼好处，因为幼童本身即是低风险的族群，他们本来就比罹患败血症的成人容易存活。

Methods: Twenty-four male SD rats were randomly divided into normal control (NC, n=6), protein C activator (PCA, n=6), lipopolysaccharide (LPS, n=6) and LPS+PCA group (n=6). NC group were given normal saline and PCA group were injected protein C activator (0.4 mg/kg) through vein of the tail. LPS group were administered lipopolysaccharide (10 mg/kg, 4h) by intraperitoneal injection method to make the model of septic shock rats. After the animal model was made, LPS+PCA group were injected protein C activator (0.4 mg/kg) through vein of the tail. 30 minutes after the injection, each rat was tested by Medlab biosignal analyzing system for observing mean arterial pressure and left ventricle function, the activity of LDH and iNOS in myocardium and the cuttings of myocardial tissues.

取SD雄性大鼠24只随机分成对照组、PCA组、LPS组和LPS+PCA组四组，对照组尾静脉注射生理盐水，PCA组尾静脉注射蝮蛇毒蛋白C激活物，LPS组腹腔注射LPS (10 mg/kg， 4h)的方法建立败血症休克的实验动物模型，在建立败血症的实验动物模型的基础上，尾静脉注射PCA (0.4 mg/kg)为LPS+PCA组，每只大鼠均于药后30 min时运用Medlab生物信号采集处理系统记录平均动脉压和左心室功能指标，并测定心肌中乳酸脱氢酶活性、诱导性一氧化氮合酶活性及心肌病理切片。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。