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The thiopeptides, by binding within a cleft located between the ribosomal protein L11 and helices 43 and 44 of the 23S rRNA, overlap with the position of domain V of EF-G, thus explaining how this class of drugs perturbs translation factor binding to the ribosome.

核糖体蛋白L11和23SrRNA的43/44螺旋结构形成裂隙,L11的构象变化能够加宽该裂隙从而允许延伸因子EF-G插入,促使GTP水解,为肽链延伸合成过程中核糖体的构象变化提供能量,而Thio能够与L11和23sRNA结合,阻止L11的构象变化,使该裂隙处于闭合状态,抑制EF-G在延伸过程中的作用。

The beasts were distributed along the phalanxes, each elephant having assigned to it a thousand men in coats of mail, with bronze helmets, and five hundred picked cavalry.

把象分编成队,每只象旁站一千人,都身披铠甲,头戴铜盔;又为每只象派有精骑五百。

If it walks like a duck, and quacks like a duck, it's duck-like enough for our purposes.

如果它走起来象鸭子,并且叫声也象鸭子,那么它是足够象鸭子的。

Sometimes a tame elephant is tethered nearby to give the wild one confidence and in most cases the captive gradually quietens down and begins to accept its food.

有时把一头驯服的象拴在四周以取得野象的信任,大多数情况下,新捕的象会逐渐安静下来,并开始接受喂饲的食物。

Sometimes a tame elephant is tethered nearby to give the wild one confidence and in most cases the captive gradually quietens down and begins to accept its food.

有时把一头驯服的象拴在附近以取得野象的信任,大多数情况下,新捕的象会逐渐安静下来,并开始接受喂饲的食物。

Sometimes a tame elephant is tethered nearby to give the wild one confidence, and in most cases the captive gradually quietens down and begins to accept its food.

这种极端的事例虽不可全信,但强调了一项基本原则,象和驯象员之间的关系是驯象成功与否的关健。

Sometimes a tame elephant is tethered nearby to give the wild one confidence, and in most cases the captive gradually quietens down and begins to accept its food.

有时,把一头已驯服的象拴在旁边能给野象以信心。在大多数情况下,刚博来的象会慢慢静下来,接着开始吃食。

Sometimes a tame elephant is tethered nearby to give the wild one confidence, and in most cases the captive gradually quietens down and begins to accept its food.

有时,把一头已驯服的象拴在旁边能给野象以信心。在大多数情况下,刚捕来的象会慢慢静下来,接着开始吃食。

"Sometimes a tame elephant is tethered nearby to give the wild one confidence, and in most cases the captive gradually quietens down and begins to accept its food."

人们有时把一头已驯服的象栓在近旁以给野象以信心,在大多数情况下俘获象会逐渐安静下来,并接受喂食。

"Sometimes a tame elephant is tether ed nearby to give the wild one confidence, and in most cases the captive gradually quietens down and begins to accept its food."

人们有时把一头已驯服的象栓在近旁以给野象以信心,在大多数情况下俘获象会逐渐安静下来,并接受喂食。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力