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Objective To investigate the dynamic expression of insulin-like growth factor 1 receptor in the posterior retina, refractive error and eye axial length after intravitreous injection of IGF-1R antisense oligonucleotides; to study the role of IGF-1R in the development of form-deprivation myopia in the guinea pig. Methods Sixty-four 3-week-old guinea pigs were included in the study.

目的 观察豚鼠形觉剥夺性近视眼后极部视网膜胰岛素样生长因子1受体(insulin-like growth factor 1 receptor, IGF-1R)基因表达水平的动态变化,以及IGF-1R反义寡核苷酸玻璃体腔注射对形觉剥夺性近视眼屈光度及眼轴长度的影响,探讨视网膜IGF-1R在实验性近视眼发病中的作用。

Moreover, the water extract and the alkaloids of Rhizoma Coptidis, as well as berberine, palmatine and jatrorrhizine could increase the EFSinduced contraction.

为了验证我们的这种推测,本文研究黄连水提物、黄连总生物碱以及黄连中的主要化学成分小檗碱、巴马丁碱和药根碱对豚鼠胃窦环行肌收缩的影响。

Objective To investigate the effects of different Leptospira strains on phagocytosis of peritoneal macrophages of guinea pigs, and explore the role of innate immune in the pathogenesis of leptospirosis.

目的 通过比较不同毒力钩端螺旋体对豚鼠腹腔巨噬细胞吞噬功能的影响,探讨固有免疫在钩端螺旋体病发病机制中的作用。

It was demonstrated that the expression of collagenase from Leptospira interrogans was detected in the lungs of a guinea pig model of leptospirosis, where the leptospirae distributed.

钩体病豚鼠模型的肺组织中有胶原酶的表达,并且存在于有钩端螺旋体分布的部位。

The result fights allergic experiment to show, dispel the wind stops land of can different level restrains urticant Ding allergy of akin and passive skin mixes the bandicoot that antiserum causes 2, the sex of small rat late hair of chloric benzene be caused by exceeds 2 nitro- of 4- quick the thymus index that reaction; still can increase small rat when dosage greatly and lienal index; stop urticant experiment shows, dispel the wind stops urticant Ding can reduce the time of fit of small rat itching with dextrose lead anhydride and itching duration apparently, can increase Guinea pig to be able to bear or endure those who suffer phosphoric acid histamine send urticant threshold.

结果抗过敏试验显示,祛风止痒酊能不同程度地抑制抗血清诱发的大鼠同种被动皮肤过敏和2,4-二硝基氯苯所致的小鼠迟发性超敏反应;大剂量时还可增加小鼠的胸腺指数及脾指数;止痒试验显示,祛风止痒酊能明显降低右旋糖酐诱导的小鼠搔痒发作次数及搔痒持续时间,并能增加豚鼠耐受磷酸组胺的致痒阈。

The dynamic changes of mammiferous hsp70 epitope related proteins were tested with modified western blotting.

结果 抗哺乳类hsp70单克隆抗体识别上述各种细菌抗原均非hsp70家族,正常豚鼠膜迷路表达hsp70水平极低。

Methods use monoclonal antibody against mammiferous hsp70 to recognize the related antigens of Bacillus pyocyaneus,Bacillus proteus,Bacillus coli,Staphylococcus aureus and Klebsiella pneumoniae with modified western blotting.

用抗哺乳类热休克蛋白(heat shock protein,hsp)70抗体识别绿脓杆菌、变形杆菌、大肠杆菌、金黄色葡萄球菌和肺炎克雷白杆菌抗原,进行免疫转印分析,测试正常豚鼠膜迷路中hsp70的表达水平。

The result of study showed that quercetin promotes the proliferation of melanocytes and synthesis of melania in the skin of guinea pigs.

槲皮素对棕黄色豚鼠背部皮肤有增色作用,具有促进黑素细胞增殖和黑素合成的功能。

VZV was sensitive to Vero cells and not sensitive to the primary simple-lager cells from Meriones unguiculatus kidney, fetal rabbit kidney and fetal guinea pig kidney, lung and spleen.

VZV对Vero细胞敏感;对沙鼠肾,胎兔肾,胎豚鼠肾、肺、脾原代单层细胞不敏感;对乳小白鼠不敏感。

METHODS: The spiral modiolar artery in guinea pig cochlea was exposed by microsurgery, then the fluorogold or horseradish peroxidase was given around the SMA for retrograde tracing.

在正常豚鼠单侧耳蜗螺旋蜗轴动脉局部滴加逆行追踪剂辣根过氧化物酶或荧光金,观察双侧交感颈上神经节、星状神经节内HRP或FG逆标神经元的分布;采用逆标与免疫组化相结合的双重标记方法观察追踪阳性神经元是否表达酪氨酸羟化酶、神经肽Y、钙基因相关肽或P物质。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。