说明的

In addition, some modifications on several computational methods are also presented. Using LMTO method the electronic structure of several systems are studied, and some results are obtained. They are: The ideal Nb (100) surface has three surface states, the multi-layer relaxed surface has two surface states. The surface energy of the ideal surface is higher than that of the relaxed surface, that means that the multi-layer relaxed surface is more stable than the former one, which supports the LEED results. The mono-layer relaxed Ag (111) surface is the most stable one among several" stable surface models"presented by several researchers. The surface energy of Ag (111) surface is higher than that of surface Ag (001), which supports some experimental results such as different reaction rate at different surface orientations for the same material. The surafce states of Si (111) surface not only locate near the Fermi level, but also in the valence band, which agrees well with Cohen's conclusion. Si (111)-H is an effective model for analysing the surface states and H adsorbed on the back surface is a good method for improving the convincingness of the results obtained on thinner slab models. The surface stability depends on three different kinds of MoSi〓(001) surfaces, the surface with mono-layer Si is the most stable one, and the surface with Mo at the first layer is the most unstable one among them. These are consistant with the Kemoda's experimental results. The valence bands of clean or K adsorbed CdTe (111) surface agrees well with the synchrotron radiation studies. The surface of CdTe (111) consists of four kinds of surface models which show different surface electronic structures and different surface structure stabilities. The conclusion agrees well with Wu's experimental work. The different absorbed alkali metals on the CdTe (111) surface give different adsorption characteristics which have relations not only with the valence electrons, but also with the core ones of the alkali metals. The electonic structures of Si-C alloys are different from that of Si-Ge alloys, and the energy band gaps of Si-C alloys do not increase linearly with Carbon concentration, our conclusion supports Alexander's results, but conflicts with Soref's one.

现分述如下： LMTO方法及其应用方面：1）通过对Nb（100）表面电子态分析发现清洁理想表面有三个表面态，多层弛豫表面有两个表面态；表面能大小说明多层弛豫表面更稳定，支持了LEED结果。2）通过对采用不同方法获得的几种不同Ag（111）表面稳定结构的表面能计算分析，给出了单层弛豫表面为Ag（111）表面的最稳定结构；从Ag（111）单层弛豫表面和Ag（001）表面的表面能比较，发现了Ag（001）表面表面能要比Ag（111）小的，表明了同种物质不同表面取向将表现出不同物理、化学性质，这是与实验中得出的结论是吻合的，3）通过对Si（111）表面态分析，不仅发现了Si（111）表面不仅具有居于费米能级附近的悬挂键所对应的表面态，而且还有很多表面态位于价带能量范围内，与Cohen等结果一致，H饱和slab模型背表面相当于增加了slab层的厚度，是一有效的变相增加slab层厚的方法，弛豫表面较清洁理想表面价带谱们低能端的少许移动，预示着总能降低，说明弛豫表面较清洁理想表面稳定。4）MoSi〓具有三种表面，从费米能级上态密度值大小得到单层Si表面最稳定，Mo原子为表层原子的表面最不稳定，双层Si原子表面居中的结论，这与Kemoda等人实验结果是一致的。5）通过对CdTe（111）表面表面电子态、表面结构稳定性及表面H、碱金属吸附的电子结构系列研究，不仅得出了CdTe（111）清洁及碱金属K吸附价带谱与同步辐射光电子谱相吻合的结果，而且发现了CdTe（111）表面具有四类不同原子近邻特征，表现出四类不同的表面结构及电子结构特征：不同表面态分布、不同的表面结构稳定性（表层原子与次层原子成三键有一悬挂键的表面要比表层原子与次层原子成一键有三悬挂键稳定（与Wu等人实验结果一致））、不同的H吸附特性。

To investigate whether the expression of cdc2 and cyclin B1 in spermatogenic cells during spermatogenesis is actually a temperature dependent event, in situ hybridization, Western blotting and immunohistochemistry analysis were used to study the expression of cdc2 and cyclin B1 in normal and cryptorchid testis. Results showed that heat would differentially hurt male germ cells in different developmental stages during spermatogenesis, especially the pachytene primary spermatocytes. Most of spermatogonia in contralateral cryptorchid testis were not harmed fatally by heat as yet, indicating that spermatogonia could resist to beat to a certain extent. In this case spermatogonia could develop to pachytene/diplotene primary spermatocytes, but they could not acquire the ability to complete the transition from mitosis to meiosis, and then appeared to go through apoptosis. Therefore, we could not find the descendants of meiosis: secondary spermatocytes and round spermatids, elongated spermatids and spermatozoon. The abdominal temperature had no significant influence on the transcription of cdc2 and cyclin B1 in the spermatogonia and pachytene/diplotene primary spermatocytes. In normal rabbit testis, cyclin B1 increased in the pachytene/diplotene primary spermatocytes before meiosis and reached its peak in the spermatids.

为了解精子正常发生过程中cdc2和cyclin B1表达的低温依赖性，我们利用原位杂交和免疫组化等方法，研究了正常和隐睾精子发生过程中cdc2和cyclin B1的转录和翻译调控活动，结果表明：（1）热对各阶段的雄性生殖细胞都有损害，粗线期的初级精母细胞尤为敏感，实验性隐睾内的精原细胞尚未完全受到"致命"影响，说明精原细胞对热有一定的耐受性，但即使成为粗线期／双线期初级精母细胞，却未能获得由有丝分裂过渡到减数分裂的能力，呈现不同程度的凋亡，所以在整个切片中找不到源自减数分裂的产物----次级精母细胞、圆形精子细胞，更谈不上长形精子细胞和精子的形成；（2）腹腔高温未明显地影响隐睾精原细胞和粗线期/双线期初级精母细胞中cyclinB1和cdc2的转录，说明高温并不是通过影响cyclin B1和cdc2的转录活动而导致生精过程阻断的；（3）正常兔睾丸组织中，〓在精原细胞和粗线期／双线期精母细胞中均有表达：cyclin B1蛋白在减数分裂前期的粗线期／双线期初级精母细胞中的表达量增加，于变态末期的精子细胞中达高峰。

In such doing, this dissertation serves as a step stone for papers of its counterparts to come, and, more importantly, it proposes a strategic alternative to the realization of models for image processing. This dissertation consists of three major parts. In the first part, detailed discussions and delicate analyses of academic papers on Cellular Neural Network will be provided in the hope of helping us see the potentiality of Cellular Neural Network in the applications of image processing. I will focus on the aforementioned limitations on hardware compilation as well. In the second part, I will put forth "texture analysis" as one basic model of analysis when we apply Cellular Neural Network to image processing. In this so-called texture analysis, a useful "spatial feature" is especially drawn to help us overcome possible problems of more complicated Cellular Neural Network applications in image processing."Spatial feature" also serves as a well-functioning mechanism for technology of image identification. In the last part of this thesis, I will look into a case study, where Cellular Neural Network is applied to help de-screen document image. Using it as an example, we will see how algorithms of Cellular Neural Network may be of marvelous use in applications in document image processing, since it would reduce a great deal of calculation and computation when applied to software compilation, yet opens up unlimited possibilities for higher-speed hardware compilation of high-level image processing.

这篇论文主要可以分为三大部分：在第一部份里，我们会详细地说明并讨论在过去到现在大部分将分子类神经网路应用於影像处理的相关文献及未来所有可能的发展和技术，另外也将分子类神经网路作一完整的介绍，除此之外，我们也会特别著重於分子类神经网路在影像处理相关应用理论的讨论以及其硬体实现化的考量；在第二部分里，我们提出了一个将分子类神经网路应用於影像辨识处理的基础分析—纹路分析，这是由於纹路分析的复杂性和普遍性会使得分子类神经网路於高阶影像处理的应用不会只局限在单一的影像处理技术，其中我们也提出了一个相当有用的空间特徵，此一特徵不但可以使复杂地高阶影像处理能够应用分子类神经网路，也为影像辨识技术提供了一个很好的辨识机制；在最后一部分里，我们也将文件影像分析做了一个完整的剖析，并以文件影像的去网点为例来说明在实际情况下的分子类神经网路的应用，如此演算法的开发也为文件影像处理提供了更多实际的应用，更考量了文件影像处理若以软体实现时的计算量负荷，而对未来高阶数位影像处理能够以硬体实现来提高处理速度提供了无限的可能。

On the basis of the kinetic equation of substrate reaction in the presence of urea or guanidine hydrochloride, all microscopic kinetic constants for the free enzyme and enzyme-substrate binary and ternary complexes have been determined. The results of the present studies indicate that:①In the presence of urea or guanidine hydrochloride, enzyme-substrate complexes lose their activity less rapidly than the free enzyme. Therefore, both substrates, NADPH and 7, 8-dihydrofolate, protect dihydrofolate reductase against inactivation.②The denaturation of dihydrofolate reductase by urea follows single-phase kinetics, and changes in enzyme activity and tertiary structure proceed simultaneously in the unfolding process, so it may be an"all or none"process.③The GdnHCl-induced unfolding of the dihydrofolate shows a biphasic transition, while the change in the enzyme activity is a single exponential process. The rate constant of inactivation is consistent with that of the fast conformational change. Therefore, the kinetic intermediate of protein unfolding should be a partially folded and inactive form.

我们根据在脲或盐酸胍存在下的底物反应动力学方程求得游离酶和酶底物二元、三元复合物的微观动力学常数，结果表明：①酶-底物二元、三元复合物的失活速度明显慢于游离酶，说明两个底物二氢叶酸和NADPH对酶的失活都具有一定程度的保护作用；②在脲作用下，酶的失活和构象变化均为单指数项过程，而且酶的活力丧失和三级结构变化是同时发生的，说明二氢叶酸还原酶的脲变性可能是一个"全或无"的两态过程；③在盐酸胍作用下，酶的构象变化为两相过程，而失活则是单指数项过程，酶分子构象变化的快相速度常数与失活速度常数基本一致，因此我们认为二氢叶酸还原酶的盐酸胍变性过程中存在一个没有活力、但仍具备一定空间结构的变性中间体。

The comparisons of biochemistry between OP and OR rats The differences between OP and OR rats included not only body weight, but lipids metabolism and insulin sensitivity as well, characterized with insulin resistance, increasing in serum free fatty acids and ketone body, and hepatic TC and TG in OP rats. However, no significant differences were observed in serum TG, TC, LDL, HDL and fasting glucose between OP and OR rats.⑶Comparisons of metabolites in serum, urine and liver tissue between OP and OR rats①There were significant differences in amino acids concentration between OP and OR rats,especially in liver tissue, such as high concentrations in ketogenic and glucogenic amino acids in OP rats, suggesting differences in amino acids metabolism;② The different metabolites between OP and OR rats included increasing of various saturated fatty acids and decreasing of polyunsaturated fatty acids in OP rats;③The urinary metabolites analysis indicated that different structure or metabolism of gut microflora might exist between the two phenotypes, which probably influenced the regulation of body weight gain;④The end-products of catecholamines in urine and intermediates of krebs cycle in serum in OP rats were all up-regulated, suggesting that the activity of sympatheic nervous system and energy metabolism was higher in OP rats than OR rats.

胰岛素耐受实验和胰岛素敏感指数表明OP动物的胰岛素敏感性较OR动物下降，而OP大鼠血清中游离脂肪酸、酮体、肝脏总胆固醇和甘油三酯水平显著升高；但是，OP与OR大鼠血清中总胆固醇、甘油三酯、低密度脂蛋白、高密度脂蛋白和空腹血糖等的水平并无显著性差异；⑶肥胖易感与肥胖抵抗大鼠血清、尿液和肝脏组织提取物中代谢物的比较研究表明：①OP与OR大鼠的血清、尿液和肝组织提取物中多种氨基酸的含量存在显著差异，并以肝组织中的差异氨基酸数量为最多，包括各种生酮和生糖氨基酸水平在OP组的升高，说明氨基酸代谢的差异是两种体重表型大鼠之间存在的重要差异特征之一；②OP与OR动物肝脏和血清差异代谢物中包含多种饱和长链脂肪酸的升高如十四烷酸、十六烷酸、硬脂酸等和多不饱和脂肪酸的下降如亚油酸和花生四烯酸，说明两种体重表型动物的肝脏脂肪酸代谢存在明显差异；③长期高脂饮食喂养后，动物的尿液代谢物分析表明OP与OR动物体内的肠道菌群结构存在差异，这些菌群上的差别可能在动物体重增长的调节上产生影响；④与OR动物相比，OP动物尿液代谢物中儿茶酚胺类递质的代谢终产物如高香草酸、扁桃酸和4-羟基苯乙酸明显升高。

Were extracted by different extracting solvents in lab, the results indicated that with the increasing of Mn concentration levels, the speciation of Mn in their roots transform from H2O-extractable species to HCl-extractable species and NaCl-extractable species, showed increases of Mn of oxalate binding and pectate binding or prontein binding in cell wall of roots; Mn of H2O-extractable species were 34.55～50.26% of total Mn in stems and increased with the increasing of Mn concentration levels, which benefited upward transport of Mn; Percentage of Mn of H2O-extractable species were 38.55～44.19% and Mn of HCl-extractable species were 20.66～28.74% to total Mn in leaves, suggesting that most Mn in leaves were the speciation of H2O-solubility organic salts or manganese oxalates. 5. Chlorophyll in leaves of Polygonum hydropiper L.

不同的提取剂对水蓼根、茎、叶的提取结果表明，随着锰处理浓度增加，水蓼根中Mn由水提取态向盐酸提取态和氯化钠提取态转化，说明根细胞壁结合的草酸盐和果胶酸盐或蛋白质结合态的Mn含量随锰处理浓度的增加而增加；在茎中，水提取态锰含量占总锰的34.55-50.26%，且随锰处理的增加其水提取态锰的比例增加，这有利于锰向上运输；水蓼的叶片中，水提取态锰占总锰的38.55-44.19%，盐酸提取态锰占总锰的20.66-28.74%，说明叶片中的锰大部分以水溶性有机盐或草酸锰的形态存在。

This paper first analyses and summarizes the ststus quo and evolution trend of encryption, some common used cryptograph are introduced, including the algorithms used in symmetric cryptosystem and asymmetirc cryptosystem. We describe the theory of each algorithms and compare the elliptic curve cryptosystem with the other two asymmetric cryptosystems to show the advantages of this algorithm. Second, the principle of ECC is discussed, including the math foundation of ECC, basic conception of elliptic curves, constructiong idea of ECC, operation on the elliptic curve and so on. Third, the current attacks of ECC were analyzed deeply, and an algorithm based on limited prime number field was constructed. We analyzed its realizability in theory, and implement it by using certain function of MIRACL software package. Latter half in this paper, the implementation model of a simple elliptic curve encryption system which based on GF has been introduced. The paper also put a deep analysis on the algorithm of point addition and point multiplication.

本文首先对密码技术的发展现状及其发展趋势进行了分析和综述，详细的介绍了私钥密码系统和公钥密码系统的发展，说明各种算法的原理和优缺点，并给出了一些典型的密码体制的简要分析，重点将椭圆曲线算法与其它几种公钥密码算法比较，说明椭圆曲线算法的优势；其次，探讨了椭圆曲线密码体制的原理，包括椭圆曲线密码的数学基础、基本概念、椭圆曲线密码体制的构造思想等问题；第三作者对椭圆曲线的攻击现状作了详细的分析，针对所使用的大素数域F_p，设计了素数域上安全椭圆曲线产生的算法，从理论上做了可实施性分析，从软件上做了具体实现；在本文的后半部分，提出了一个简单的基于有限素数域上的椭圆曲线加密方按算实现模型，并对SECES中设计的点加和点乘运算进行了深入分析。

In this thesis, how to study and apply of system of CRM based on Web are discussed. Firstly, we summarize the principle of CRM, beginning with the current research condition, and introduce the concept, features and management principle of CRM. Secondly, we illustrate the basic architecture of web-based CRM system to form the basis of the further research and propose the integration of CRM system to the front end of enterprise, namely, the study on the business process re-engineering of CRM system. Then we discuss the key technique knowledge on CRM system based on Web, which included the technology of system interface, system safety and the design of net framework. And explain the technology of web service is a good solution to the problem of system interface in the Internet and the advantage of the develop way based on the B/S pattern. According to an application of CRM system based on Web, this thesis explains how to set up a CRM system based on Web, which include the customer requirement, analyzing the business process, system framework and system safety. At last, this thesis puts forward the extensive foreground of the system of web-based CRM with the expanding of the web technology and explains that there are some questions are to be resolve stilly in this thesis.

本文的研究内容首先从客户关系管理的研究现状出发，对客户关系管理加以概述，阐述CRM系统概念、系统特点和核心管理思想；并阐明了基于Web的CRM系统的基本架构为进一步的研究作铺垫，提出CRM系统对企业前端的整合，即对CRM系统的业务流程重构的研究；接下来说明基于Web的CRM系统开发的关键技术，包括系统体系结构的选择，系统接口以及系统安全三方面的技术要求，具体说明了B/S模式的原理及优点，Web Service是解决基于B/S模式系统的接口问题的最好方案；然后以一个销售管理CRM系统为例，说明如何构建一个基于Web的CRM系统，包括了系统设计要求、系统实现、系统功能框架和系统安全机制；最后根据当前通信和网络技术的发展，展望基于Web的CRM系统应用的广泛前景，并对在本文研究中还存在需要改进的地方进行了探讨。

The effect of zeolites ion-exchanged by transition metals on thermal catalytic cracking reaction is studied. The product distributions of the cracking reactions catalyzed by theβor ZSM-5 zeolites exchanged with transition metals are different from that catalyzed by corresponding Hzeolites, which means the mechanism of cracking reactions has varied. Group Ⅷ metals Fe, Co, Ni and Cu, Zn are shown to be of strong catalytic activity of oxidative dehydrogenation, while Ti and Cr are not of oxidative activity. Catalyzed by zeolites or catalyst containing Ag, conversion of thermal catalytic cracking reactions and the yield of ethylene increase while the yield of propylene does not decrease. Silver can not only promote the formation of carbonium ion, but also convert carbonium ion into free-radical via redox reaction. The weak adsorption of olefins on silver reduces the occurrence of hydrogen transfer and dehydrogenation. As a result, the yield of light olefins is favored by silver in the catalyst.

采用过渡金属交换的分子筛作为催化剂，进行催化热裂解制取乙烯的反应，研究发现，在β沸石分子筛和ZSM-5分子筛中引入过渡金属后，催化热裂解反应的产物分布与相应的氢型分子筛相比有了较大的变化，说明过渡金属的加入对于催化热裂解反应的机理具有影响，Ⅷ族金属如Fe、Co、Ni和第Ⅰ、Ⅱ副族Cu、Zn表现出较强的氧化脱氢活性，产物中氢气、焦炭的产率很高，Ti、Cr则未表现出氧化作用：分子筛及催化剂中引入银后，催化热裂解反应的转化率和乙烯的产率有了提高，丙烯产率没有很大的变化，说明银在催化热裂解反应中能够促进正碳离子的生成，又有可能通过氧化-还原作用部分改变反应机理，促进了自由基的生成，并且由于银对烯烃的吸附很弱，其氢转移反应和脱氢、加氢活性比较低，有利于烯烃产率的提高。

This dissertation is based on the historical development and the current situation in Pingyao's tourism market, through tourists' poll on the spot and internet, analyzes the overall constitution of the tourists generating market of Pingyao by means of combination of economic and geographic measures through the view of spatial scale and demography, including the total amount of the tourists in Pingyao, the constitution of realistic tourist generating market and potential tourist generating market, the nature of the tourist generating market in Pingyao. The thesis establishes an ACD matrix with the occupation of tourist as a main factor to analyze the relationship between tourist flows and their occupations, with the combination of quantitative and qualitative method to take an insight into the tourist segments selected, in the hope of advising a scientific measure and practicable basis for future development of Pingyao's tourism industry in order to convert the present dilemmatic situation to an optimization.

数据发布平台，依据淡季和春节对平遥旅游者抽样调查问卷资料、网络电子邮件问卷和其他有关历史和现状资料，采用地理分析与市场分析相结合的手段，从空间尺度、人口学特征等方面综合分析了平遥旅游客源市场的总体特征：平遥旅游市场总量状况、现实客源地和潜在客源地构成现状、平遥旅游客源市场的基本特征；对以客源地作为平遥细分市场的分析方法进行了研究，构建出ACD矩阵指导目的地对客源地的选择和细分，进而描述性说明每一类客源地细分市场进入细分选择的依据；将职业特征作为人群细分的标准，通过说明职业特征的高度相关性，以职业细分了平遥的客源市场，定量和定性相结合，分析每一类入选的细分人群，为平遥旅游客源细分市场提供科学的方法，作为平遥下一步开发旅游产品、设计旅游项目的依据，以实现平遥旅游资源的优势转化。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失