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Part I Role of glycogen synthase kinase 3 in squamous differentiation induced by cigarette smoke in porcine airway epithelial cell Squamous differentiation of airway epithelium induced by diverse stimuli, such as cigarette smoke, has been thought to be an adaptive response to chronic injury as well as a precancerous lesion of lung squamous carcinoma.

第一部分糖原合成酶激酶3在吸烟诱导的猪气道上皮细胞鳞状分化中的作用研究气道上皮的鳞状细胞化生常见于慢性支气管炎症、致癌剂刺激等,一般被认为是对慢性损伤的一种适应性反应,也是肺鳞癌的癌前病变,其分子机制尚未完全阐明。

In our islet transplantation program nonhuman primates with STZ-induced diabetes received transplants under chronic immunosuppression including calcineurin inhibitors, drugs in the rapamycin class affecting growth factor-induced cell proliferation, and the sphingosine 1-phosphate receptor antagonist FTY720. Four animals developed renal failure and had to be sacrificed, most likely caused by cyclosporine.

在我们应用STZ诱导的糖尿病的灵长类动物性胰岛细胞移植的病例长期应用的免疫抑制剂包括:钙神经素拮抗剂,雷帕霉素和神经鞘氨醇1-磷酸盐FTY720.4个动物死于肾功能衰竭,这很可能是由于环孢素引起的。

Diet induced thermogenesis is different for each nutrient based on the amount of ATP required for the initial steps of metabolism and storage.

饮食诱导的产热是不同的每个养分的基础上,数额三磷酸腺苷所需的初始步骤的代谢和储存。

Although Albee also described the use of calcium phosphates as an alternative to bone in the 1920s, it was not until 1965, when Marshall Urist identified "bone formation by autoinduction"2, that new options unfolded.

尽管Albee也曾在1920年代提出过使用硫酸钙作为骨的替代品,但直到1965年Marshall Urist确定了&自身诱导的成骨&,新的选择展现在了我们的面前。23年后Wozney小组及Luyten小组发现了引起这一现象的蛋白BMPs-2、 3和4。

Although Albee also described the use of calcium phosphates as an alternatie to bone in the 1920s, it was not until 1965, when Marshall Urist identified "bone formation by autoinduction"2, that new options unfolded.

尽管Albee也曾在1920年代提出过使用硫酸钙作为骨的替代品,但直到1965年Marshall Urist确定了&自身诱导的成骨&,新的选择展现在了我们的面前。23年后Wozney小组及Luyten小组发现了引起这一现象的蛋白BMPs-2、 3和4。

In the cytosol preparations, nimodipine inhibited the iNOS enzymatic activity induced by LPS +〓 in mouse astroglia cells with an 〓 value of 0.036±0.003mM and nNOS activity in mouse neurons with an 〓 value of 0.047±0.003mM, but did not affect the eNOS activity in bovine cerebral endothelial cells.

在体外培养细胞制备的匀浆液,尼莫地平抑制由LPS+〓诱导的星型胶质细胞的iNOS活性,〓为0.036±0.003mM,同时还抑制神经元的nNOS活性,IC50为0.047±0.003mM,但对牛脑微血管内皮细胞的eNOS活性无明显影响。

The result fights allergic experiment to show, dispel the wind stops land of can different level restrains urticant Ding allergy of akin and passive skin mixes the bandicoot that antiserum causes 2, the sex of small rat late hair of chloric benzene be caused by exceeds 2 nitro- of 4- quick the thymus index that reaction; still can increase small rat when dosage greatly and lienal index; stop urticant experiment shows, dispel the wind stops urticant Ding can reduce the time of fit of small rat itching with dextrose lead anhydride and itching duration apparently, can increase Guinea pig to be able to bear or endure those who suffer phosphoric acid histamine send urticant threshold.

结果抗过敏试验显示,祛风止痒酊能不同程度地抑制抗血清诱发的大鼠同种被动皮肤过敏和2,4-二硝基氯苯所致的小鼠迟发性超敏反应;大剂量时还可增加小鼠的胸腺指数及脾指数;止痒试验显示,祛风止痒酊能明显降低右旋糖酐诱导的小鼠搔痒发作次数及搔痒持续时间,并能增加豚鼠耐受磷酸组胺的致痒阈。

Shearing force can induce molecular orientation with different mesomorphic behaviors at different temperature. Electric field induce biphenyl mesogens align parallel to the direction of applied electric field.

通过本论文的工作,阐述了含联苯液晶基元的硬主链型侧链液晶聚炔及其单体的结晶与液晶行为、结晶形貌和外场诱导的分子取向行为,为开发新型高性能材料提供必要的结构依据。

Meanwhile, we have found that some strains of Lactobacillus were related to the onset and development of diabetes when we studied the relationships between gut microbiota and STZ induced diabetes model through molecular ecological methods.

此外,我们实验室在采用分子生态学的方法来研究肠道菌群与STZ诱导的ICR小鼠糖尿病之间的关系时,发现一些乳杆菌与糖尿病的发生发展存在一定的关系。

The results showed that HGF not influenced the proliferation and osteogenic differentiation of bone marrow-derived mesenchymal stem cells.

结果表明,重组人HGF不影响骨髓间充质干细胞的增殖和向成骨细胞的分化,但可明显促进骨髓间充质干细胞的迁移并抑制anoikis诱导的细胞凋亡;PI-3K和MAPK途径参与了HGF促进细胞迁移的作用。

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She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了,但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

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Several theories about reigniting and extinguishing of the arc have been refered.

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