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Objective To Study the expression of Foxp3,TGF-β1 and the changes of IL-2,IL-10 in trinitrobenzene sulphonic acid-induced colitis rats and normal rats,and elucidate the function and mechanism of Foxp3 in IBD.

目的观察2、4、6-三硝基苯磺酸诱导的SD大鼠结肠炎模型结肠Foxp3、TGF-β1的表达及外周血IL-2、IL-10的变化,初步确定Foxp3在IBD中的作用及机制。

To get more informationon gene regulation during erythroid differentiation of K562 cells, we applied modifieddifferential display reverse transcription polymerase chain reaction methodto identify genes showing differential expression in uninduced and hemin-induced K562cells.

为进一步获得分化过程中相关基因表达的信息,我们应用改良的差异显示RT-PCR技术,分析K562细胞在Hemin诱导的红系分化前后的基因表达变化,共获得357条差异表达带。

While with the Coriolis force omitted, the flow in the cavity is under the influence of centrifugal buoyancy force, which can develop from stable to unstable as this force enhances. The centrifugal buoyancy force could lead to flow unstably.

哥氏力垂直于〓与〓构成的平面,对径向速度导致切向作用力,对切向速度导致径向作用力,在该力的作用下盘腔内轴向通流诱导的旋涡被压扁,尽管涡强有所增加,但是盘面的平均换热基本减弱。

The anti-inflammation test showed that within the concentration of 1-100 μg/ml both usnic acid material and SMEDDS had no cytotoxic action. The usnic acid material and SMEDDS with different dosage could bring the levels of the mouse peritoneal macrophage releasing TNF-α induced by thermal inactivation bacillus coli down, and it showed a dose-dependent relationship.

抗炎实验表明,松萝酸原料及自微乳在1~100μg/ml质量浓度范围内对小鼠腹腔巨噬细胞无显著细胞毒作用;不同质量浓度的原料药和自微乳制剂均可使热灭活大肠杆菌诱导的TNF-α水平有不同程度的下降,并呈一定的量-效关系。

Notably, depletion of endoplasmic reticulum Ca2+ stores by thapsigargin, or blockade of Ca2+ release from these stores by ryanodine receptor inhibitors, mimics and occludes the effects of presynaptic presenilin inactivation.

值得注意的是,毒胡萝卜素存储内质网Ca2+的缺失或兰尼受体拮抗剂诱导的Ca2+释放阻滞将会模拟并阻止该作用的发生。

MethodsThe pharmacological effects of the Ziziphus jujube leaf extract on the autonomic activities of mice, the time of sleep induced by pentobarbital sodium, the sleeping synergistic action of mice with barbital sodium at sub-threshold and hypnotic dosages and the central inhibitory effects in mice induced by amphetamine were investigated.

目的观察酸枣叶提取物对中枢神经系统作用。方法考察酸枣叶提取物对小鼠自主活动的影响、对延长戊巴比妥钠诱导的小鼠睡眠时间、对阈下巴比妥钠的睡眠协同作用以及对苯丙胺中枢兴奋作用的影响。

Methods: In order to discuss the JIANGU granule treatment GIO molecular action mechanism, this research takes the osteoporosis sickness animal experimentation model by the glucocorticoids-induced induction domestic rabbit, through HE dyeing research Chinese native medicine JIANGU granule to vacancy bone sunken number influence; Through the immunity histochemistry technology,observes the blood vessel bast growth factor in the bone tissue expression. Through home position hybrid technology,in mRNA member level research, collagen I mRNA distribution and expression.

本研究以糖皮质激素诱导的家兔作为骨质疏松症动物实验模型,通过HE染色研究中药健骨冲剂对骨组织的空缺骨陷窝数的影响;通过免疫组织化学技术,观察血管内皮生长因子在骨组织的表达;通过原位杂交技术,在mRNA分子水平研究,Ⅰ型胶原mRNA在骨组织中分布及表达。

Therefore, the production of SA in inner and outer cortexes was triggered by AM fungi firstly, then diffused through intercellular space, and accumulated in vascular tissue.

因此,GUS活性的组织表达特异性结果进一步证实了SA在AM真菌诱导的抗/耐线虫病害的ISR信号传导途径中起着重要的信号物质作用。

However, no previous reports have detected serum autoantibodies such as that reported with DILI from halothane or isoflurane.

然而,这些澥道中没有检测患者血清中的自身澗体,而既往的氟烷或异氟醚诱导的肝损害则检测过患者血清中的自身澗体。

Hypnotics lead to a kind of drug-induced hangover, with daytime drowsiness and increased chance of accidents; they also have a high incidence of dependence even after a short term course and withdrawal has adverse effects.

安眠药,导致1种药物诱导的宿醉,与白天嗜睡和增加的机会,发生意外的机会;他们也有发病率高的依赖,甚至后,短期课程,并撤回了不利影响。

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