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Simvastatin leads to the high expression of cbfa1 in bone marrow stromal cells and increased ALP activity, which may be parts of the mechanisms underlying the anabolic osteogenetic effect of simvastatin.

本研究采用体内给药然后体外对骨髓基质细胞培养诱导的方法,旨在观察辛伐他汀对骨髓基质细胞成骨分化的影响,以探讨其促进骨形成,治疗骨质疏松的机制。

PDTC inhibit the NFkB binding activity and the level of phospho- GSK-3β(Ser9) in hypertrophic heart tissues and thereby attenuates the development of cardiac hypertrophy.

为此,本研究以压力负荷增加诱导的小鼠心肌肥大为模型,进一步探讨PDTC抑制NF-κB活性的机制,并观察PDTC对心肌肥大发生发展的影响。

Here, we examined the effects of rehabilitative therapies on proliferation and survival of distinct glial populations in the perilesional area of photochemically induced focal ischemic infarcts in the forelimb sensorimotor cortex in rats.

现在,作者设计一项实验来检测康复训练对光化学诱导的局灶性脑缺血损伤灶周围(梗死灶位于大鼠前肢感觉运动皮质功能区)的不同胶质细胞种群增殖和存活的影响。

Results The ponderal index of brain, thoracic gland and spleen and SOD activity are significantly decreased, while the MDA content increased (P.01) in D-galactose-induced subacute mice. Shouwu soft capsule can improve the ponderal index of brain, thoracic gland and spleen and the SOD activity in blood serum and brain tissue and reduce MDA content.

结果:D-半乳糖诱导的亚急性衰老小鼠脑、胸腺和脾的重量指数明显下降,SOD活性明显下降(P.01),MDA含量明显提高(P.01)等衰老改变,首乌软胶囊能够提高亚急性衰老小鼠脑、胸腺和脾的重量指数,提高血清和脑组织中SOD(P.01)活性,降低MDA含量(P.01)。

Antigen-driven T cells maintained in culture using this combined cytokine regimen can be induced to grow and maintained functional in large numbers and survive long-term in cultrue with each antigen restimulation cycle prolonged to six weeks. The IL-2 doses used in this combined cytokine regimen can be reduced 10 to 100 times that of cultures using IL-2 alone.

结果表明:单独使用IL-2或IL-7均能增强T细胞对ConA或特异性抗原刺激诱导的增殖反应,但联合使用IL-2和IL-7具有更加显著的协同刺激作用。C57BL/6小鼠抗FBL-3肿瘤特异性T细胞系在IL-2与IL-7联合培养系统中,不但T细胞数量明显增加,且能在保持特异性功能的同时,延长T细胞体外抗原刺激周期。

Expression of CB and PV in adult rat OB was regulated reversibly by deafferentation induced by Triton.

大鼠嗅球中CB和PV的表达受triton诱导的传入神经阻滞的可逆调控。

METHODS According to In-ternational Society for Clinical Visual Electrophysiology's standard program,we recorded the scotopic electroretino-graph,oscillatory potentials,photopic electroretinographand30Hz flicker response in diabetic rats for2weeks,by using REPIport system,Ag-AgCl corneal contact electrode and stainless steel needle elec┐trode.

按照国际临床视觉电生理学会的标准化方案,采用REPIport系统和银-氯化银角膜电极以及不锈钢针状电极对链脲霉素诱导的糖尿病大鼠模型进行2wk的暗适应视网膜电图、振荡电位、明适应视网膜电图和30Hz闪烁反应记录(30Hz flicker)。

Results Blood sugar level was decreased by Merine collagen peptide ,but The blood sugar did not change significatively during the experiment .

目前认为,糖尿病的发生机制与胰岛素抵抗和机体高血糖、高血脂等因素诱导的抗氧化应激功能失调有显著的相关性。

Furthermore, within such REM episodes behavior-dependent modulation of the subcortically driven theta rhythm is also reproduced.

此外,在REM事件中行为依赖的皮下层诱导的θ节律的调节也再生了。

A turbidimetric method was used to measure human washed platelet aggregations induced by O2 and effects of APNF(0134) on them.

并以比浊法观察了O2诱导的人洗涤血小板的聚集及APNF(0134)对其的影响。

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